rpatnaik.bme's picture
Dr. Ranjana Patnaik
Professor
Electrophysiology Lab, School of Biomedical Engineering
rpatnaik.bme@iitbhu.ac.in
9453984462
Area of Interest: 
Neurophysiology, Electrophysiology, Biomaterials, Biochemistry

Image result for ranjana patnaik

Currently, I am working as Professor in School of Bio-Medical Engineering, Indian Institute of Technology (Banaras Hindu University), Varanasi. I have thirty-three years of Professional and Research Experience. I have guided Research for thesis supervisor and examiner for Ph.D./ M.Tech/IDD of more than 40 students. I have authored, co-authored or edited nine book chapters, four Journals and more than 150 research articles, reviews and several papers that I published or read in many meetings,  workshops, seminars and colloquiums at various institutions of higher learning. I am the member of numerous Boards such as Board of Governors, Board of studies and Board of Examiners in different Universities and Institutions. I have received a number of Awards such as Rashtriya Gaurav Award (2014), Best Citizen of India Award (2014), Rajiv Gandhi Excellence Awards (2014), National Award 2011 (by Department of Science and Technology, Govt. of India) for Low Cost Multi-use Hearing Aid and Saraswati Samman (2010). I have worked in several National and International sponsored projects. I am the life member of eight Scholarly Societies including SFN, IBRO, IAN, IBNS, FICCI, APS, BNA and FENS. My areas of interests are Stroke, Heat/Cold Stress, Blood-Brain Barrier, Neurotoxicity, Neurodegeneration, and Neuroprotection.

Neuroprotection

Educational Qualifications:

  • Ph.D. (1992)

Physiology, “Role of Histamine Blood-Brain Barrier in Stress”
Institute of Medical Sciences, Banaras Hindu University, Varanasi

  • M.Sc. (1975) - First Division & Distinction in Biochemistry

Faculty of Science, Banaras Hindu University, Varanasi

  • B.Sc. (1973) - First Position & Distinction in Chemistry

Faculty of Science, Banaras Hindu University, Varanasi

  • Diploma in Music (1973) - First Position

Faculty of Performing Arts, Banaras Hindu University, Varanasi

Neuroprotection
Present employment/affiliation and posts held previously in IIT (BHU), Varanasi:

Position From
Professor 01/01/2010
Coordinator 26/08/2006
Associate Professor 27/07/1998
Assistant Professor 25/02/1985
Research/Review Articles in Peer Reviewed Journals
(Impact Factor Source: SCI/SCI-Expanded)
 
2018
  1. Kumar G, Paliwal P, Mukherjee S, Patnaik N, Krishnamurthy S, Patnaik R. Pharmacokinetics and Brain Penetration Study of Chlorogenic Acid in Rats. Xenobiotica. 2018 Feb 24. DOI: https://doi.org/10.1080/00498254.2018.1445882 (Impact Factor: 1.93)
  2. Sharma HS, Muresanu DF, Lafuente JV, Patnaik R, Tian ZR, Ozkizilcik A, Castellani RJ, Mössler H, Sharma A. Co-Administration of TiO2 Nanowired Mesenchymal Stem Cells with Cerebrolysin Potentiates Neprilysin Level and Reduces Brain Pathology in Alzheimer’s Disease. Molecular neurobiology. 2018 Jan 1;55(1):300-11. (Impact Factor: 6.1)
  3. Patnaik R, Sharma A, Skaper SD, Muresanu DF, Lafuente JV, Castellani RJ, Nozari A, Sharma HS. Histamine H3 Inverse Agonist BF 2649 or Antagonist with Partial H4 Agonist Activity Clobenpropit Reduces Amyloid Beta Peptide-Induced Brain Pathology in Alzheimer’s Disease. Molecular neurobiology. 2018 Jan 1;55(1):312-21. (Impact Factor: 6.1)
  4. Lafuente JV, Sharma A, Muresanu DF, Ozkizilcik A, Tian ZR, Patnaik R, Sharma HS. Repeated Forced Swim Exacerbates Methamphetamine-Induced Neurotoxicity: Neuroprotective Effects of Nanowired Delivery of 5-HT3-Receptor Antagonist Ondansetron. Molecular neurobiology. 2018 Jan 1;55(1):322-34. (Impact Factor: 6.1)
  5. Sharma A, Muresanu DF, Lafuente JV, Sjöquist PO, Patnaik R, Tian ZR, Ozkizilcik A, Sharma HS. Cold environment exacerbates brain pathology and oxidative stress following traumatic brain injuries: potential therapeutic effects of nanowired antioxidant compound h-290/51. Molecular neurobiology. 2018 Jan 1;55(1):276-85. (Impact Factor: 6.1)
  6. Ozkizilcik A, Sharma A, Muresanu DF, Lafuente JV, Tian ZR, Patnaik R, Mössler H, Sharma HS. Timed release of cerebrolysin using drug-loaded titanate nanospheres reduces brain pathology and improves behavioral functions in Parkinson’s disease. Molecular neurobiology. 2018 Jan 1;55(1):359-69. (Impact Factor: 6.1)
  7. Wiklund L, Patnaik R, Sharma A, Miclescu A, Sharma HS. Cerebral Tissue Oxidative Ischemia-Reperfusion Injury in Connection with Experimental Cardiac Arrest and Cardiopulmonary Resuscitation: Effect of Mild Hypothermia and Methylene Blue. Molecular neurobiology. 2018 Jan 1;55(1):115-21. (Impact Factor: 6.1)
 
2017
  1. Paul S, Sinha T, Patnaik R. Feedforward neural network based classification cans possibly a novel tool to evaluate the neuronal condition in rat model. Journal of the Neurological Sciences. 2017 Oct 15;381:981. (Impact Factor: 2.29)
  2. Wiklund L, Patnaik R, Sharma A, Miclescu A, Sharma HS. Cerebral Tissue Oxidative Ischemia-Reperfusion Injury in Connection with Experimental Cardiac Arrest and Cardiopulmonary Resuscitation: Effect of Mild Hypothermia and Methylene Blue. Molecular Neurobiology. 2017 Sep 11:1-7. (Impact Factor: 6.1)
  3. Ozkizilcik A, Sharma A, Muresanu DF, Lafuente JV, Tian ZR, Patnaik R, Mössler H, Sharma HS. Timed Release of Cerebrolysin Using Drug-Loaded Titanate Nanospheres Reduces Brain Pathology and Improves Behavioral Functions in Parkinson’s Disease. Molecular Neurobiology. 2017 Sep 5:1-1. (Impact Factor: 6.1)
  4. Sharma  HS,  Muresanu  DF,  Lafuente  JV,  Patnaik  R,  Tian  ZR,  Ozkizilcik  A,  Castellani  RJ,  Mössler  H, Sharma  A.  Co-Administration  of  TiO2  Nanowired  Mesenchymal  Stem  Cells  with  Cerebrolysin Potentiates  Neprilysin  Level  and  Reduces  Brain  Pathology  in  Alzheimer’s  Disease.  Molecular Neurobiology. 2017 Aug 26:1-2. (Impact Factor: 6.1)
  5. Sharma A, Muresanu DF, Lafuente JV, Sjöquist PO, Patnaik R, Tian ZR, Ozkizilcik A, Sharma HS. Cold environment exacerbates brain pathology  and oxidative stress following traumatic brain injuries: potential therapeutic effects of nanowired antioxidant compound h-290/51. Molecular neurobiology. 2017 Aug 30:1-0. (Impact Factor: 6.1)
  6. Kumar G, Paliwal P, Patnaik R. Withania somnifera Phytochemicals Confer Neuroprotection by Inhibition of the Catalytic Domain of Human Matrix Metalloproteinase-9. Letters in Drug Design & Discovery.2017;14:1-0. (Impact Factor: 0.974)
  7. Lafuente JV, Sharma A, Muresanu DF, Ozkizilcik A, Tian ZR, Patnaik R, Sharma HS. Repeated Forced Swim Exacerbates Methamphetamine-Induced Neurotoxicity: Neuroprotective Effects of Nanowired Delivery  of  5-HT3-Receptor  Antagonist  Ondansetron.  Molecular  Neurobiology.  2017  Aug  31:1-3.(Impact Factor: 6.1)
  8. Kumar G, Patnaik R. Inhibition of Gelatinases (MMP-2 and MMP-9) by Withania somnifera Phytochemicals Confers Neuroprotection in Stroke: An In Silico Analysis. Interdisciplinary Sciences: Computational Life Sciences. 2017. DOI: 10.1007/s12539-017-0231-x (Impact Factor: 0.853)
  9. Mukherjee, S., Kumar, G. and Patnaik, R. Identification of potential inhibitors of PARP-1, a regulator of caspase-independent cell death pathway, from Withania Somnifera phytochemicals for combating neurotoxicity: a structure-based in-silico study.  Journal of Theoretical and Computational Chemistry. 2017:(Impact Factor: 0.953)
  10. Ozkizilcik A, Sharma A, Muresanu DF, Lafuente JV, Tian ZR, Patnaik R, Mössler H, Sharma HS. Timed Release  of  Cerebrolysin  Using  Drug-Loaded  Titanate  Nanospheres  Reduces  Brain  Pathology  and Improves Behavioral Functions in Parkinson’s Disease. Molecular Neurobiology. 2017:1-1.  (Impact Factor: 6.1)
  11. Kumar, G., Mukherjee, S. and Patnaik, R. Identification of Withanolide-M and Stigmasterol as Potent neuroprotectant and Dual inhibitor of Inducible/Neuronal Nitric Oxide Synthase by Structure-Based Virtual Screening. Journal of Biological Engineering Research and Review, 2017, 4(1), pp.09-13.
  12. Kumar  G,  Paliwal  P,  Patnaik  N,  Patnaik  R.  Withania  somnifera  phytochemicals  confer neuroprotection  by  selective  inhibition  of  nNos:  An  in  silico  study  to  search  potent  and  selective inhibitors  for  human  nNOS.  Journal  of  Theoretical  and  Computational  Chemistry.  2017: doi.org/10.1142/S0219633617500420 (Impact Factor: 0.953)
 
 2016
  1. Sharma HS, Muresanu DF, Lafuente JV, Nozari A, Patnaik R, Skaper SD, Sharma A. Pathophysiology of Blood-brain barrier in Brain Injury at cold and hot environments. Novel drug targets for neuroprotection. CNS & neurological disorders drug targets. 2016 Sep 2. (Impact Factor: 2.18)
  2. Sharma H, Muresanu D, Lafuente J, Patnaik R, Moessler H, Tian ZR, Sharma A. Nanodrug delivery of a multimodal novel drug cerebrolysin reduces engineered nanoparticles induced aggravation of heat stroke induced ubiquitin expression and brain pathology. Brain Injury, 2016 Jan 1, Vol. 30, No. 5-6, pp. 505-506 (Impact Factor: 1.808)
  3. Sharma, A., Muresanu, D., Lafuente, J.V., Patnaik, R., Tian, Z.R., Moessler, H. and Sharma, H.S., 2016, January. Cold environment exacerbates brain pathology and oxidative stress following traumatic brain injuries. Potential therapeutic effects of nanowired cerebrolysin. Brain Injury, Vol. 30, No. 5-6, pp. 506-506 (Impact Factor: 1.808)
  4. Muresanu, D.F., Sharma, A., Patnaik, R., Nozari, A., Tian, Z.R., Ozkizilcik, A., Moessler, H. and Sharma, H.S., 2016, January. Nanodelivery of cerebrolysin induces profound neuroprotection in heat stroke following chronic hypertension in combination with carbon nanoparticles induced exacerbation of brain damage. Brain Injury, Vol. 30, No. 5-6, pp. 506-507 (Impact Factor: 1.808)
  5. Pandey AK, Shukla SC, Bhattacharya P, Patnaik R. A possible therapeutic potential of quercetin through inhibition of μ-calpain in hypoxia induced neuronal injury: a molecular dynamics simulation study. Neural Regeneration Research. 2016 Aug 1;11(8):1247. (Impact Factor: 0.968)
  6. Kumar G, Patnaik R. Exploring neuroprotective potential of Withania somnifera phytochemicals by inhibition of GluN2B-containing NMDA receptors: An in silico study. Medical Hypotheses. 2016, 92, 35–43. (Impact Factor: 1.136)
  7. Sharma HS, Muresanu DF, Lafuente JV, Patnaik R, Tian ZR. Need to Explore Nanodelivery of Stem Cells with Multimodal Drug like Cerebrolysin for Effective Strategies for Enhanced Neuroprotection and Neurorecovery in Neurodegenerative Disorders. Int J Nanomater Nanotechnol Nanomed 2 (1): 013. 2016;14(013):5-8.
2015
  1. Sharma HS, Patnaik R, Sharma A, Lafuente JV, Miclescu A, Wiklund L. Cardiac Arrest Alters Regional Ubiquitin Levels in Association with the Blood–Brain Barrier Breakdown and Neuronal Damages in the Porcine Brain. Molecular neurobiology. 2015:1-11. (Impact Factor: 5.137)
  2.  Sharma HS, Muresanu DF, Lafuente JV, Sjöquist P-O, Patnaik R, Sharma A. Nanoparticles Exacerbate Both Ubiquitin and Heat Shock Protein Expressions in Spinal Cord Injury: Neuroprotective Effects of the Proteasome Inhibitor Carfilzomib and the Antioxidant Compound H-290/51. Molecular neurobiology. 2015:1-17. (Impact Factor: 5.137)
  3. Sharma HS, Kiyatkin EA, Patnaik R, Lafuente JV, Muresanu DF, Sjöquist P-O, et al. Exacerbation of Methamphetamine Neurotoxicity in Cold and Hot Environments: Neuroprotective Effects of an Antioxidant Compound H-290/51. Molecular neurobiology. 2015:1-11. (Impact Factor: 5.137)
  4. 4.   Sharma A, Muresanu DF, Lafuente JV, Patnaik R, Tian ZR, Buzoianu AD, et al. Sleep Deprivation-Induced Blood-Brain Barrier Breakdown and Brain Dysfunction are Exacerbated by Size-Related Exposure to Ag and Cu Nanoparticles. Neuroprotective Effects of a 5-HT3 Receptor Antagonist Ondansetron. Molecular neurobiology. 2015:1-15. (Impact Factor: 5.137)
  5. S Sharma H, Feng L, V Lafuente J, F Muresanu D, R Tian Z, Patnaik R, et al. TiO2-Nanowired Delivery of Mesenchymal Stem Cells Thwarts Diabetes-Induced Exacerbation of Brain Pathology in Heat Stroke: An Experimental Study in the Rat Using Morphological and Biochemical Approaches. CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS & Neurological Disorders). 2015;14(3):386-99. (Impact Factor: 3.021)
  6. Pandey AK, Bhattacharya P, Shukla SC, Paul S, Patnaik R. Resveratrol inhibits matrix metalloproteinases to attenuate neuronal damage in cerebral ischemia: a molecular docking study exploring possible neuroprotection. Neural Regeneration Research. 2015;10(4):568. (Impact Factor: 0.180)
  7. Muresanu DF, Sharma A, Lafuente JV, Patnaik R, Tian ZR, Nyberg F, et al. Nanowired Delivery of Growth Hormone Attenuates Pathophysiology of Spinal Cord Injury and Enhances Insulin-Like Growth Factor-1 Concentration in the Plasma and the Spinal Cord. Molecular neurobiology. 2015:1-9. (Impact Factor: 5.137)
 

2014

  1. Sharma HS, Muresanu DF, Vannemreddy P, Patnaik R, Sharma A. Cold and hot environment exacerbates brain pathology following concussive brain injury. Brain Injury. 2014;28(5-6):524-5. (Impact Factor: 1.808)
  2. Sharma HS, Muresanu DF, Patnaik R, Moessler H, Sharma A. Traumatic brain injury induced blood-brain barrier disruption, brain oedema formation and brain pathologies are reduced by cerebrolysin in a dose-dependent manner. An experimental study in the rat using biochemical and morphological approaches. Brain Injury. 2014;28(5-6):524 (Impact Factor: 1.808)
  3. Sharma HS, Muresanu D, Nozari A, Patnaik R, Moessler H, Sharma A. Nanoparticles Aggravate Cardiac Arrest-Induced Blood-Brain Barrier Breakdown, Edema Formation, and Neuronal Injuries: Neuroprotective Effects of a Multimodal Drug Cerebrolysin. Cell Transplantation. 2014;23(6):782-3. (Impact Factor: 3.127)
  4. Sharma HS, Menon PK, Lafuente JV, Aguilar ZP, Wang YA, Muresanu DF, Mössler H, Patnaik R, Sharma A. The role of functionalized magnetic iron oxide nanoparticles in the central nervous system injury and repair: new potentials for neuroprotection with Cerebrolysin therapy. Journal of nanoscience and nanotechnology. 2014;14(1):577-95. (Impact Factor: 1.556)
  5. Sharma HS, Menon P, Lafuente JV, Muresanu DF, Tian ZR, Patnaik R, et al. Development of in vivo drug-induced neurotoxicity models. Expert opinion on drug metabolism & toxicology. 2014;10(12):1637-61. (Impact Factor: 2.831)
  6. Sharma A, Muresanu DF, Patnaik R, Prasad V, Sharma HS. Anaesthetics influence closed head injury induced blood-brain barrier disruption, cerebral blood flow, brain oedema and brain pathology. Brain Injury. 2014;28(5-6):522-3. (Impact Factor: 1.808)
  7. Sharma A, Muresanu D, Patnaik R, Huang H, Tian Z, Moeessler H, et al. Superior Neuroprotective Efficacy of Nanodrug Delivery of Cerebrolysin Compared to Other Neurotrophic Factors in Concussive Head Injury. Cell Transplantation. 2014;23(6):782-. (Impact Factor: 3.127)
  8. Paul S, Bhattacharya P, Pandey A, Patnaik R. Application of Mathematical Modelling as a Tool to Analyze the EEG Signals in Rat Model of Focal Cerebral Ischemia. Journal of The Institution of Engineers (India): Series B. 2014;95(1):23-7.
  9. Feng L, Sharma A, Muresanu D, Patnaik R, Tian Z, Sharma HS. Nanowired Delivery of Mesenchymal Stem Cells (MSCs) Attenuates Pathophysiology of Spinal Cord Injury and Enhances Brain-Derived Neurotrophic Factor and Insulin-Like Growth Factor-1 Concentrations in the Plasma and the Spinal Cord. Cell Transplantation. 2014;23(6):769-70. (Impact Factor: 3.127)
  10. Bhattacharya P, Pandey AK, Paul S, Patnaik R. Melatonin renders neuroprotection by protein kinase C mediated aquaporin-4 inhibition in animal model of focal cerebral ischemia. Life sciences. 2014;100(2):97-109. (Impact Factor: 2.702)
  11. Bhattacharya P, Pandey AK, Paul S, Patnaik R. Alleviation of glutamate mediated neuronal insult by piroxicam in rodent model of focal cerebral ischemia: a possible mechanism of GABA agonism. Journal of physiology and biochemistry. 2014;70(4):901-13. (Impact Factor: 1.969)
 2013
  1. Sharma HS, Patnaik R, Sharma A, Wiklund L. The contribution of glial cells and water channel aquaporin-4 in the neuropathology of cardiac arrest is still ignored. CNS & neurological disorders drug targets. 2013;12(1):3. (Impact Factor: 2.628)
  2. Sharma HS, Muresanu DF, Patnaik R, Sharma A. Exacerbation of brain pathology after partial restraint in hypertensive rats following SiO2 nanoparticles exposure at high ambient temperature. Molecular neurobiology. 2013;48(2):368-79. (Impact Factor: 5.137)
  3. Sharma HS, Muresanu DF, Patnaik R, Moessler H, Sharma A, editors. Neurotoxicity of single walled carbon nanotubes (SWCNT, 2-10 nm) and neuroprotection by TiO2 nanowired delivery of cerebrolysin. Amino Acids; 2013. (Impact Factor: 3.293)
  4. Sharma HS, Muresanu D, Patnaik R, Sharma A, editors. Nanoparticles Exacerbate Brain Pathology and Sensory Motor Disturbances Following Concussive Brain Injury. Cell Transplantation; 2013. (Impact Factor: 3.127)
  5. Sharma H, Sharma A, Patnaik R, Muresanu D. Opioid receptors influence blood–/INS; brain barrier permeability, cerebral blood flow and serotonin levels following forced swimming exercise in young rats. Journal of the Neurological Sciences. 2013 (333):e590. (Impact Factor: 2.243)
  6. Sharma H, Patnaik R, Sharma A, Wiklund L. Cardiac arrest alters regional ubiquitin levels in the porcine brain. Neuroprotective effects of methylene blue. Journal of the Neurological Sciences. 2013 (333):e164-e5. (Impact Factor: 2.243)
  7. Sharma H, Castellani R, Muresanu D, Smith M, Patnaik R, Moessler H, et al. Diabetes exacerbates Alzheimer's disease induced brain pathology. Possible neuroprotective effects of Cerebrolysin. Journal of the Neurological Sciences. 2013;333:e301. (Impact Factor: 2.243)
  8. Sharma A, Muresanu DF, Patnaik R, Sharma HS. Size-and age-dependent neurotoxicity of engineered metal nanoparticles in rats. Molecular neurobiology. 2013;48(2):386-96. (Impact Factor: 5.137)
  9. Sharma A, Muresanu D, Patnaik R, Sharma HS, editors. Blood-Brain Barrier Breakdown and Brain Dysfunction Following Sleep Deprivation Are Exacerbated by Size-Related Nanoparticles. Cell Transplantation; 2013. (Impact Factor: 3.127)
  10. Paul S, Bhattacharya P, Pandey A, Sharma N, Tiwari J, Patnaik R. A strategic application of fast Fourier transform as a novel tool to evaluate the extent of neuronal insult in rat model of focal cerebral ischemia. Bangladesh Journal of Medical Physics. 2013;5(1):29-36.
  11. Pandey AK, Bhattacharya P, Shukla SC, Paul S, Patnaik R. Neuroprotective effects of quercetin in chemical hypoxia: in silico evaluation of the hypothesis exploring PKC inhibition-mediated pharmacotherapy. Medicinal Chemistry Research. 2013;22(10):4836-41. (Impact Factor: 1.402)
  12. Pandey AK, Bhattacharya P, Paul S, Patnaik R. Rhamnetin Attenuates Oxidative Stress and Matrix Metalloproteinase in Animal Model of Ischemia/Reperfusion: A Possible Antioxidant Therapy in Stroke. American Journal of Neuroprotection and Neuroregeneration. 2013;5(1):49-55.
  13. Muresanu DF, Sharma A, Patnaik R, Moessler H, Sharma HS, editors. Cerebrolysin restores amino acid neurotransmitters balance in the brain following traumatic head injury: an experimental study in the rat. Amino Acids; 2013. (Impact Factor: 3.293)
  14. Muresanu D, Sharma A, Patnaik R, Moessler H, Sharma H. Nanowired cerebrolysin attenuated exacerbation of blood–brain barrier breakdown, edema formation and brain pathology after heatstroke in diabetic and hypertensive rats. Journal of the Neurological Sciences. 2013 (333):e163. (Impact Factor: 2.243)
  15. Muresanu D, Sharma A, Patnaik R, Moessler H, Sharma H, editors. Blood-Brain Barrier Breakdown, Edema Formation, Nitric Oxide Synthase Upregulation and Brain Pathology in Diabetic and Hypertensive Rats Following Heat Stroke: Neuroprotective Effects of Titanium Nanowired Cerebrolysin. Cell Transplantation; 2013. (Impact Factor: 3.127)
  16. Menon P, Muresanu D, Sharma A, Aguilar Z, Wang Y, Lafuente J, Moessler, H., Patnaik, R., Sharma, Hari Shanker . Functionalized Magnetic Iron Oxide Nanoparticles Influence Spinal Cord Trauma-Induced Pathology: Neuroprotective Effects of Cerebrolysin Treatment. Cell Transplantation; 2013. (Impact Factor: 3.127)
  17. Bhattacharya P, Pandey AK, Shukla SC, Paul S, Patnaik R. Neuroprotection by μ-calpain and matrix metalloproteinases inhibition by Piroxicam in cerebral ischemia: an in silico study. Medicinal Chemistry Research. 2013;22(11):5112-9. (Impact Factor: 1.402)
  18. Bhattacharya P, Pandey AK, Paul S, Patnaik R, Yavagal DR. Aquaporin-4 inhibition mediates piroxicam-induced neuroprotection against focal cerebral ischemia/reperfusion injury in rodents. PloS one. 2013;8(9):e73481. (Impact Factor: 3.234)
  19. Bhattacharya P, Pandey AK, Paul S, Patnaik R. Does Piroxicam really protect ischemic neurons and influence neuronal firing in cerebral ischemia? An exploration towards therapeutics. Medical hypotheses. 2013;81(3):429-35. (Impact Factor: 1.152)
  20. Bhattacharya P, Pandey A, Paul S, Patnaik R. Attenuation of glutamate mediated neuronal insult by piroxicam in animal model of focal cerebral ischemia: Possible involvement of GABA agonism. Journal of the Neurological Sciences. 2013;333:e163. (Impact Factor: 2.243)
2012
  1. Vicente Lafuente J, Sharma A, Patnaik R, Fior Muresanu D, Shanker Sharma H. Diabetes exacerbates nanoparticles induced brain pathology. CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS & Neurological Disorders). 2012;11(1):26-39. (Impact Factor: 3.021)
  2. Sharma HS, Muresanu D, Patnaik R, Sharma A, editors. Exacerbation of Stress Symptoms, Sensory Motor Dysfunction, and Brain Pathology After Partial Restraint in Hypertensive Rats Following Silica Dust (SiO2 Nanoparticles) Exposure at High Ambient Temperature. Cell Transplantation; 2012. (Impact Factor: 3.127)
  3. Sharma A, Muresanu D, Patnaik R, Sharma HS, editors. Age-and size-dependent neurotoxicity of engineered nanoparticles from metals. European Journal of Neurology; 2012. (Impact Factor: 4.162)
  4. Sharma A, Muresanu D, Patnaik R, Lafuente J, Sharma HS, editors. Engineered nanoparticles Ag, Cu and Al (50-60nm) induce oxidative stress, neuronal nitric oxide synthase upregulation and brain pathology. Neuroprotection by Insulin-like growth factor1. European Journal of Neurology; 2012. (Impact Factor: 4.162)
  5. Rout N, Paul S, Waghmare P, Patnaik R. Low cost multi-use hearing aid. Bangladesh Journal of Otorhinolaryngology. 2012;18(1):36-41.
  6. Paul S, Bhattacharya P, Pandey A, Sharma N, Patnaik R, editors. FFT: an effective tool to prove the degree of neuronal insult after focal cerebral ischaemia in animal model. Journal of Neurology; 2012: (Impact Factor: 3.578)
  7. Pandey AK, Verma S, Bhattacharya P, Paul S, Mishra A, Patnaik R. An in-silico strategy to explore neuroprotection by quercetin in cerebral ischemia: A novel hypothesis based on inhibition of matrix metalloproteinase (MMPs) and acid sensing ion channel 1a (ASIC1a). Medical hypotheses. 2012;79(1):76-81. (Impact Factor: 1.152)
  8. Muresanu D, Sharma A, Patnaik R, Sharma HS, editors. Enhanced neuroprotection by nanowired delivery of cerebrolysin in hyperthermia-induced brain damage. Cell Transplantation; 2012. (Impact Factor: 3.127)
  9. Bhattacharya P, Pandey AK, Paul S, Patnaik R. Neuroprotective potential of Piroxicam in cerebral ischemia: An in silico evaluation of the hypothesis to explore its therapeutic efficacy by inhibition of aquaporin-4 and acid sensing ion channel1a. Medical hypotheses. 2012;79(3):352-7. (Impact Factor: 1.152)
  10. Bhattacharya P, Pandey AK, Paul S, Patnaik R. Combination therapy of Ifenprodil with Piroxicam may be an effective therapeutic intervention in cerebral stroke: a hypothesis. Medical hypotheses. 2012;79(4):516-8. (Impact Factor: 1.152)
  11. Bhattacharya P, Pandey AK, Paul S, Patnaik R. Cognitive effects of NSAIDs in cerebral ischemia: A hypothesis exploring mechanical action mediated pharmacotherapy. Medical hypotheses. 2012;79(3):393-5. (Impact Factor: 1.152)
  12. Bhattacharya P, Pandey AK, Paul S, Patnaik R. Aquaporin-4 in cerebral edema following ischemia/reperfusion injury: exploration of novel therapeutic strategies. American Journal of Neuroprotection and Neuroregeneration. 2012;4(2):90-116.
  13. Bhattacharya P, Pandey A, Paul S, Patnaik R, editors. Aquaporin-4 as a therapeutic target for neuroprotection by piroxicam in rat model of focal cerebral ischaemia. JOURNAL OF NEUROLOGY; 2012: (Impact Factor: 4.162)
 2011
  1. Wiklund L, Patnaik R, Sharma A, Sharma HS, editors. Redistribution of calcitonin-gene related peptide (CGRP) in the brain and heart tissues after cardiac arrest. Neuroprotection by methylene blue treatment. AMINO ACIDS; 2011: (Impact Factor: 3.293)
  2. Vicente Lafuente J, Patnaik R, Sharma A, Sharma HS, editors. Engineered nanoparticles from metals influence glutamate, aspartate, GABA and glycine neurotransmission in the normal and injured spinal cord. Amino Acids; 2011: (Impact Factor: 3.293)
  3. Sharma S, Patnaik R, Sharma N, Tiwari J. Simulated annealing-based particle swarm optimisation with adaptive jump strategy for modelling of dynamic cerebral pressure autoregulation mechanism. International Journal of Bio-Inspired Computation. 2011;3(4):225-37. (Impact Factor: 3.969)
  4. Sharma HS, Muresanu DF, Patnaik R, Stan AD, Vacaras V, Perju-Dumbrava L, et al. Superior neuroprotective effects of cerebrolysin in heat stroke following chronic intoxication of Cu or Ag engineered nanoparticles. A comparative study with other neuroprotective agents using biochemical and morphological approaches in the rat. Journal of nanoscience and nanotechnology. 2011;11(9):7549-69. (Impact Factor: 1.556)
  5. Sharma HS, Ali SF, Patnaik R, Zimmermann-Meinzingen S, Sharma A, Muresanu DF. Cerebrolysin attenuates heat shock protein (HSP 72 KD) expression in the rat spinal cord following morphine dependence and withdrawal: possible new therapy for pain management. Current neuropharmacology. 2011;9(1):223. (Impact Factor: 3.049)
  6. Sharma H, Patnaik R, Sharma A, Muresanu D. F108 CEREBROLYSIN ATTENUATES BLOOD‐SPINAL CORD BARRIER DISRUPTION, ASTROCYTIC ACTIVATION AND NEURONAL DAMAGE IN THE RAT SPINAL CORD FOLLOWING FORMALIN NOCICEPTION. European Journal of Pain Supplements. 2011;5(S1):105 (Impact Factor: 2.928)
  7. Sharma H, Patnaik R, Sharma A. S141 NANOPARTICLES FROM METALS ENHANCE MORPHINE WITHDRAWAL RESPONSE, BLOOD–BRAIN BARRIER DISRUPTION AND BRAIN PATHOLOGY IN RATS. NEUROPROTECTION BY ONDANSETRON TREATMENT. European Journal of Pain Supplements. 2011;5(1):208. (Impact Factor: 2.928)
  8. Sharma H, Muresanu D, Patnaik R, Sharma A, Lafuente J. S138 COCAINE ENHANCES GP120 TRANSPORT IN THE RAT BRAIN AND EXACERBATES BLOOD–BRAIN BARRIER DISRUPTION AND NEUROTOXICITY. NEUROPROTECTIVE EFFECTS OF CEREBROLYSIN. European Journal of Pain Supplements. 2011;5(1):207. (Impact Factor: 2.928)
  9. Sharma H, Muresanu D, Patnaik R, Dora S, Vitalie V, Laura P, et al., editors. SUPERIOR NEUROPROTECTIVE EFFECTS OF CEREBROLYSIN IN HEAT STROKE FOLLOWING NANOPARTICLES TREATMENT. A COMPARATIVE STUDY WITH OTHER STROKE PROTECTING AGENTS IN THE RAT. EUROPEAN JOURNAL OF NEUROLOGY; 2011: (Impact Factor: 4.162)
  10. Sharma H, Muresanu D, Patnaik R, Dora S, Vitalie V, Laura P, et al., editors. SUPERIOR ANTIOXIDANT EFFECTS OF CEREBROLYSIN IN HEAT STROKE FOLLOWING Cu AND Ag NANOPARTICLES TREATMENT: A COMPARATIVE STUDY WITH OTHER STROKE THERAPIES IN THE RAT. EUROPEAN JOURNAL OF NEUROLOGY; 2011: (Impact Factor: 4.162)
  11. Pandey AK, Hazari PP, Patnaik R, Mishra AK. The role of ASIC1a in neuroprotection elicited by quercetin in focal cerebral ischemia. Brain research. 2011;1383:289-99. (Impact Factor: 2.843)
  12. Muresanu DF, Patnaik R, Sharma A, Sharma HS, editors. Nanowired cerebrolysin restores imbalance of excitatory and inhibitory amino acid neurotransmitters in the CNS following hyperthermia induced brain pathology. Amino Acids; 2011: (Impact Factor: 3.293)
  13. Muresanu D, Patnaik R, Sharma A, Sharma H, editors. EXACERBATION OF NEURONAL AND INDUCIBLE NITRIC OXIDE SYNTHASE (NOS) UPREGULATION IN DIABETIC HYPERTENSIVE RATS AFTER HEAT STROKE. NEUROPROTECTION WITH NEURONAL AND INDUCIBLE NOS ANTIBODIES. EUROPEAN JOURNAL OF NEUROLOGY; 2011: (Impact Factor: 4.162)
  14. Muresanu D, Patnaik R, Sharma A, Sharma H, editors. Engineered Nanoparticles From Metals Ag, Cu, and Al (50-60 nm) Induce Oxidative Stress, Blood-Brain Barrier Disruption, Neuronal Nitric Oxide Synthase Upregulation, and Cell Injury in the Rat Brain. Neuroprotective Effects of Insulin Like Growth Factor-1. CELL TRANSPLANTATION; 2011: (Impact Factor: 3.127)
 
 2010
  1. Sharma S, Patnaik R, Sharma N, Tiwari J. Modelling of dynamic cerebral pressure autoregulation using sequential genetic algorithm. International Journal of Mathematical Modelling and Numerical Optimisation. 2010;1(4):299-315.
  2. Sharma HS, Patnaik R, Sharma A. Diabetes aggravates nanoparticles induced breakdown of the blood–brain barrier permeability, brain edema formation, alterations in cerebral blood flow and neuronal injury. An experimental study using physiological and morphological investigations in the rat. Journal of nanoscience and nanotechnology. 2010;10(12):7931-45. (Impact Factor: 1.556)
  3. Sharma H, Patnaik R, Sharma A. Exposure of manganese nanoparticles induce blood-brain barrier disruption, brain pathology and cognitive and motor dysfunctions in rats. EUROPEAN JOURNAL OF NEUROLOGY; 2010: (Impact Factor: 4.162)
  4. Shanker Sharma H, Patnaik R, Sharma A. Diabetes Aggravates Nanoparticles Induced Breakdown of the Blood-Brain Barrier Permeability, Brain Edema Formation, Alterations in Cerebral Blood Flow and Neuronal Injury. An Experimental Study Using Physiological and Morphological Investigations in the Rat. Journal of nanoscience and nanotechnology. 2010;10(12):7931. (Impact Factor: 1.556)
  5. Pandey A, Hazari PP, Kamlesh KM, Patnaik R , Mishra AK,. Noninvasive assessment of tumor hypoxia with 99m Tc labeled Schiff base derivative of metronidazole. Indian J Nucl Med. 2010 Jul-Sep; 25(3): 78–87
  6. Pandey A, Hazari P, Varshney R, Uppal J, Patnaik R, Mishra A, editors. Comparative Evaluation of Tc-99m-labeled DTPA-bis (2-nitroimidazole) and 2-Nitroimidazole for Hypoxia Imaging. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING; 2010: SPRINGER 233 SPRING ST, NEW YORK, NY 10013 USA. (Impact Factor: 5.383)
  7. Muresanu D, Patnaik R, Sharma A, Sharma H, editors. Intracerebroventricular administration of TNF-alpha antibodies reduces heat stress induced blood-brain barrier disruption and brain pathology in normotensive and hypertensive rats. EUROPEAN JOURNAL OF NEUROLOGY; 2010: (Impact Factor: 4.162)
 
2009-2006
  1. Sharma HS, Ali S, Tian ZR, Patnaik R, Patnaik S, Lek P, Sharma A, Lundstedt T. Nano- drug delivery and neuroprotection in spinal cord injury. J Nanosci Nanotechnol. 2009 Aug; 9(8):5014-37. PMID: 19928182 (Impact Factor: 1.556)
  2. Sharma HS, Patnaik R, Sharma A, Sjquist PO, Lafuente JV. Silicon dioxide nanoparticles  (SiO2, 40-50 nm) exacerbate pathophysiology of traumatic spinal cord injury and deteriorate functional outcome in the rat. An experimental study using pharmacological and morphological approaches. J Nanosci Nanotechnol. 2009 Aug; 9(8):4970-80. PMID: 19928175 (Impact Factor: 1.556)
  3. Sharma HS, Muresanu D, Sharma A, Patnaik R. Cocaine-induced breakdown of the blood- brain barrier and neurotoxicity. Int Rev Neurobiol. 2009; 88: 297-334. PMID: 19897082(Impact Factor: 2.457)
  4. Sharma HS, Patnaik R, Patnaik S, Mohanty S, Sharma A, Vannemreddy P; Antibodies to  Serotonin attenuated closed head injury induced BBB disruption and Brain Pathology,  Ann N Y Acad Sci, 2007 Dec; 1122:295-312 (Impact Factor: 4.039)
  5. 77. Sharma HS, Ali SF, Dong W, Tina ZR, Patnaik R, Patnaik S ,Sharma A ,Boman A, Lek P   Seifert E,Lundstedt T; Drug Delivery to the spinal cord tagged with Nanowire Enhances Neuroprotective. Ann N Y Acad Sci.2007 Dec, 1122:197-218. (Impact Factor: 4.039)
  6. Vannemreddy P, Ray AK, Patnaik R, Patnaik S, Mohanty S, Sharma HS. Zinc protoporphyrin IX attenuates closed head injury-induced edema formation, blood-brain barrier disruption, and serotonin levels in the rat. Acta Neurochir Suppl. 2006; 96:151-6. PMID: 16671445 (Impact Factor: 1.766)
  7. H.S Sharma, V.Prasad, R.Patnaik, S.Patnaik and S.Mohanty: Histamine Receptors Influence Blood-Spinal Cord Barrier Permeability,Edema Formation and Spinal Cord Blood Flow Changes Following Trauma to the Rat Spinal Cord. Acta Neurochir (Springer Verlag, Sweden) 2006; 96:316-21 (Impact Factor: 1.766)
 2000-1987
  1. R.Patnaik, S.Mohanty and H.S Sharma: Blockade of Histamine H2 Receptors Attenuates Blood Brain Barrier Permeability, Cerebral Blood Flow Disturbances, Edema Formation and Cell Reactions Following Hyperthermic Brain Injury in the Rat. Acta Neurochir (Suppl)(Springer Verlag, Sweden)76, 535-539, 2000 (Impact Factor: 1.766)
  2. S.K.Patnaik and R.Patnaik: Tissue-Specific Differential Induction of Aspartate Transcarbamylase by Hydrocortisone in Rats of Various Ages. Biochem Internatl.(Academic Press, Australia), 20(4), 641-647,1990
  3. S.K.Patnaik and R.Patnaik: Age-Related Differential Induction of Tryptophan Pyrrolase by Hydrocortisone in the Liver of Male Rat. Biochem Internatl. (Academic Press, Australia), 18(6),1221-1228,1989
  4. S.K.Patnaik and R.Patnaik: Tissue-Specific Differential Modulation of Arginase and Ornithine Aminotransferase by Hydrocortisone during Various Developmental Stages of the Rat. (Academic Press, Australia), 18(4), 709-719, 1989
  5. R.Patnaik,S.K Sarangi and S.K Patnaik: Tissue Specific Differential Induction of Ornithine Aminotransferase by Estradiol in Rats of Various Ages. Biochem. Internatl. (Academic Press, Australia), 14(5), 843-850, 1987
  6. S.K.Patnaik, R.Sharma and R.Patnaik: Differential Effects of Hydrocortisone on Aspartate Aminotransferase Isoenzyme of the Liver of Rats During Growth, Development        and Senescence. Biochem. Internatl. (Academic Press, Australia), 15(3), 611-617, 1987

Books/Book Chapters Published

 

  1. Sharma A, Menon PK, Patnaik R, Muresanu DF, Lafuente JV, Tian ZR, Ozkizilcik A, Castellani RJ, Mössler H, Sharma HS. Novel Treatment Strategies Using TiO2-Nanowired Delivery of Histaminergic Drugs and Antibodies to Tau With Cerebrolysin for Superior Neuroprotection in the Pathophysiology of Alzheimer's Disease. InInternational review of neurobiology 2017 Jan 1 (Vol. 137, pp. 123-165). Academic Press.
  2. Menon PK, Sharma A, Lafuente JV, Muresanu DF, Aguilar ZP, Wang YA, Patnaik R, Mössler H, Sharma HS. Intravenous Administration of Functionalized Magnetic Iron Oxide Nanoparticles Does Not Induce CNS Injury in the Rat: Influence of Spinal Cord Trauma and Cerebrolysin Treatment. International review of neurobiology 2017 Jan 1 (Vol. 137, pp. 47-63). Academic Press.
  3. Sharma HS, Patnaik R, Muresanu DF, Lafuente JV, Ozkizilcik A, Tian ZR, Nozari A, Sharma A. Histaminergic Receptors Modulate Spinal Cord Injury-Induced Neuronal Nitric Oxide Synthase Upregulation and Cord Pathology: New Roles of Nanowired Drug Delivery for Neuroprotection. International review of neurobiology 2017 Jan 1 (Vol. 137, pp. 65-98). Academic Press.
  4. Sharma HS, Feng L, Lafuente JV, Muresanu DF, Tian ZR, Patnaik R, Sharma A. Nanowired Mesenchymal Stem cells ameliorate brain pathology exacerbated by diabetes in hyperthermia. une. 2016 May 22;13:15.
  5. Sharma HS, Muresanu DF, Patnaik R, Moessler H, Sharma A. TiO2-Nanowired cerebrolysin attenuated hyperthermia induced ubiquitin overexpression and brain pathology. une. 2016 May 22;13:15.
  6. Sharma HS, Muresanu DF, Patnaik R, Tian ZR, Moessler H, Sharma A. Nano Drug delivery by Single-wall carbon nanotubes (SWCNTs) in the Central nervous system induces neurotoxicity. Potential neuroprotective effects of Cerebrolysin. une. 2016 May 22;13:15.
  7. Pandey AK, Patnaik R, Muresanu DF, Sharma A, Sharma HS. Quercetin in hypoxia-induced oxidative stress: novel target for neuroprotection. Int Rev Neurobiol. 2012;102:107-46. (Impact Factor: 2.457)
  8. Sharma HS, Patnaik R, Patnaik S, Sharma A, Mohanty S, Vannemreddy P. Antibodies to Dynorphin A (1–17) Attenuate Closed Head Injury Induced Blood–Brain Barrier Disruption, Brain Edema Formation and Brain Pathology in the Rat.  Brain Edema XIV: Springer; 2010. p. 301-6.
  9. Sharma HS, Ali SF, Tian ZR, Patnaik R, Patnaik S, Sharma A, et al. Nanowired-drug delivery enhances neuroprotective efficacy of compounds and reduces spinal cord edema formation and improves functional outcome following spinal cord injury in the rat.  Brain Edema XIV: Springer; 2010. p. 343-50.
  10. H.S.Sharma, D. F. Muresanu, A. Sharma, R. Patnaik and J. V. Lafuente: Nanoparticles influence Pathophysiology of spinal cord injury and repair: Nanoneurotoxicity and Nanoneuroprotection, Section-IV, Chapter- 9, pp-155-180, 2009
  11. H.S.Sharma, R.Patnaik, A.K.Ray and P.K.Dey: Blood-Central Nervous System Barriers in Morphine Dependence and Withdrawal: In Blood-Spinal Cord and Brain Barriers in Health and Disease(Ed By H.S.Sharma & J.Westman), Published by Academic Press,U.S.A. Chapter 16,pp..299-328,2003.
  12. Harishankar Sharma, Ranjana Patnaik and Jan Westman: Pathophysiology of Hyperthermic Brain Injury, Hyperthermia and Burn Lijbeck. Dec -4-6,2000, Germany.

 
 

 

Abstract published in conferences / Seminars / Symposia 
 

International:

  1. Gaurav Kumar, Sumedha Mukherjee, Ranjana Patnaik. Identification of chlorogenic acid as a potent multi-pathway inhibitor to combat ischemic stroke: a molecular docking simulation study. Emerging Trends in Drug Discovery and Development, IIT (BHU), Jan 18-20, 2018.
  2. S Mukherjee, G Kumar, A K Tripathi, R Patnaik. Withania somnifera phytochemicals inhibit PARP-1 for combating neurotoxicity: An in-silico approach. Emerging Trends in Drug Discovery and Development, IIT (BHU), Jan 18-20, 2018.
  3. S Mukherjee, G Kumar, B Vermani, A K Tripathi, R Patnaik. The ability of Stigmasterol to inhibit PARP-1 makes the phytochemical a potent choice for neurotherapeutics designing.  4th BSSE Annual Research Symposium, IISc , Bangalore, Jan 24-25,2018.
  4. B Vermani, S Mukherjee, G Kumar ,R Patnaik. Prolactin ameliorates cerebral ischemia in adult rat brain: an in-vivo study.  4th BSSE Annual Research Symposium, IISc , Bangalore, Jan 24-25,2018.
  5. P. Bhattacharya, A. Pandey, S. Paul, R. Patnaik : Aquaporin-4 as a therapeutic target for neuroprotection by piroxicam in rat model of focal cerebral ischaemia, accepted for Oral presentation at the 22nd  Meeting of the European Neurological Society, Prague, 09  12 June 2012.
  6. S. Paul, P. Bhattacharya, A. Pandey, N. Sharma, R. Patnaik : FFT: proves the degree of neuronal insult after focal cerebral ischemia in animal model, accepted for Poster Presentation at the 22nd  Meeting of the European Neurological Society, Prague,  09  12 June 2012.
  7. Paul S., Bhattacharya P., Pandey A. K., Sharma N., Tiwari J. P., Patnaik R., (2011). EEG: To Investigate Recovery of rat brain function following ischemic stroke, ISN-ESN 2011, 23rd Biennial Meeting at Athens, Greece.
  8. S. PAUL, R. PATNAIK, P. BHATTACHARYA, A. SHARMA, P. K. MENON, H. S. SHARMA, (2011). Engineered Nanoparticles from metals exacerbate aquaporin-4 expression, astrocytic activation, Blood-brain barrier disruption, edema formation in the brain following hyperthermia, Neuroscience 2011, Washington, DC, USA.
  9. Pallab Bhattacharya Anand Kr. Pandey, Sudip Paul, Ranjana Patnaik, (2011). Piroxicam modulates lipid peroxidation, potentiates antioxidant redox system, ameliorates behavioral outcome and electrical activity of brain in focal cerebral Ischemia. XXth World Congress of Neurology, Morocco.
  10. Pandey A.K., Hazari P. P., Kamlesh K Meena, Patnaik R., Mishra A.K., Noninvasive assessment of tumor hypoxia with 99m Tc labeled Schiff base derivative of Metronidazole. (42nd Annual Conference of the Society of Nuclear Medicine, Chandigarh, India, 11-14th November 2010)
  11. k. Pandey, P. P. Hazari, R. Varshney, J. K. Uppal, R. Patnaik, A.K. Mishra, Comparative Evaluation of 99m Tc-labeled DTPA-bis (2-nitroimidazole) and 2-Nitroimidazole for Hypoxia Imaging, (Annual Congress of European Association of Nuclear Medicine, October 9th-13th, 2010)
  12. Anand Kumar Pandey, Puja Panwar Hazari, Raunak, Niraj Singh, Harleen Khurana, Ranjana Patnaik, Anil Kumar Mishra, Neuroprotection effect of quercetin on hypoxia against induced oxidative stress in primary culture hippocampal neuronal cell. (7th Indo-Italian workshop on Chemistry and Biology of Antioxidants, University of Delhi, 16th November 2010) Poster
  13. Sharma S., Patnaik R., Modelling of cerebral pressure autoregulation using parametric ARX approach, paper International Conference on Recent trends in Mathematics and its applications, March 30-31, Department of Mathematics, Jamia Millia Islamia, 2009.
  14. Anand Kumar Pandey, Gauri Shukla, Anjani Tiwari, Ranjana Patnaik, Anil Kumar Mishra, Conjugation of Methotrexate for bone specific Radiopharmaceutical application. (9th Asia Oceania Congress of Nuclear Medicine and Biology, New Delhi, India, October 31st- Nov 4th 2008).
  15. Anand Kr. Pandey, Sudhir Kumar, Ranjana Patnaik & Abha Mishra, A novel serine protease Antiquorin from Euphorbia antiquorum: isolation and partial characterization. (International Conference on New Horizons in Biotechnology, Trivandrum, India, Nov 26th -29th, 2007. Poster
  16. R. Patnaik, S. V. Chaudhari and S. K. Patnaik: Synthesis of Anticonvulsant Semicarbazones of para- Chlorophyll derivatives and their effects on GABA Shunt. Ann. Global conf. Neuroprot. & Neuroreg., Zermatt, Switzerland, Feb, 8-10, 2004.
  17. R. Patnaik and S.K. Patnaik: Regulatory effects of Hydrocortisone on soluble phosphati date phosphohydrolase in vivo and in isolated perfused rat Liver. In Heme oxygenenase Regulation: Functions and clinical Application, Uppsala, Sweden, Spt 28-Oct 03, 2003.
  18. R. Patnaik: Histamine Receptors Influence Blood- Spinal cord Barrier Permeability, Edmema Formation and Spinal Cord Flow Changes following Trauma To the Spinal Cord. Proc. XII Int. Conf. on Brain Oedema, Hakona, Japan, Nov 10-13, 2002.
  19. R. Patnaik, H.S. Sharma and P.K. Dey: Increased Brain Water Content and Blood Brain Permeability following Immobilization Stress in Young Rats. Proc. 8th Int. Symp. On Brain Edema,Bern, Switzerland, 1999.
  20. R. Patnaik, H.S. Sharma and J. Westman: Histamine H2 Receptors Influence Hyperthermia Blood Brain Permeability Cerebral Blood Flow and Brain Edem Following Hat Stress in Rats. Proc. 1997 Symp. On Thermal Physiol., Denmark, PP. 131-134, 1997.
  21. S. K. Patnaik and R. Patnaik: Hormonal regulation of Acetylcholinesterase of the Brain during Growth, Differentiation, Adulthood and Senescence of Rats. 3rd Internatl. Symp. Neuro rec.,Hiroshima, Japan, 1990.
  22. S.K. Patnaik and R. Patnaik: Hydrocortisone- Mediated Differential Induction of Ornithine Aminotransferase6 in Rats of Various Ages. 14th Int. Cong. Bihem., Prague, Czechoslovakia, Th. 163, 1998.

National:

  1. Pallab Bhattacharya, Anand Kr. Pandey, Sudip Paul, Ranjana Patnaik, Cyclooxygenase-2 as a biomarker in cerebral ischemia: A possible neuroprotective role of Piroxicam, National conference on Biomarkers for disease-Prospects and challenges, JNIAS Hydrabad,24-25 Feb 2012.
  2. Anand Kr. Pandey, Pallab Bhattacharya, Sudip Paul, Ranjana Patnaik, Attenuation of oxidative stress and matrix metalloproteinase in ischemic stroke by rhamnetin: the evaluation of biomarker for antioxidant therapy in stroke, National conference on Biomarkers for disease-Prospects and challenges, JNIAS Hydrabad,24-25 Feb 2012.
  3. Pallab Bhattacharya, Anand Kr. Pandey, Sudip Paul, Ranjana Patnaik: Piroxicam exerts a neuroprotective action in a rat model of focal cerebral ischemia. (International Conference on Tissue Engineering and Regenerative Medicine, National Institute of Technology, Rourkela,India, September 29- October 2, 2011).
  4. Sudip Paul, N. Sharma, P. Bhattacharya, A. K. Pandey, S. Sharma, R. Patnaik: Mathematical modeling of focal cerebral ischemia using EEG data, National Conference on Mathematical Modeling and Computer Simulation, Department of Applied Mathematics, Banaras Hindu University, March 25th -27th , 2011.
  5. Pallab Bhattacharya, Anand Kr. Pandey, Sudip Paul, Ranjana Patnaik, (2011). Piroxicam exerts a neuroprotective action in a rat model of focal cerebral ischemia. International Conference on Tissue Engineering and Regenerative Medicine, National Institute of Technology, Rourkela, India.
  6. Anand Kr. Pandey, Sudhir Kumar, Ranjana Patnaik & Abha Mishra, A novel serine protease Antiquorin from Euphorbia antiquorum: isolation and partial characterization.(International Conference on New Horizons in Biotechnology, Trivendrum, India, November 26th -29th ,2007)
  7. Scientific Validation and Technical Evaluation of Ancient Medical Systems, IIT-Delhi, Feb10-11 2006.
  8. R. Patnaik, A. Kumar and S.K. Patnaik: Synthesis and Biochemical Studies of Anti Epileptic Semicarbazone Derivatives. 73rd Ann. Meet. Soc. Biol. Chem. (India), Pantanagar, Nov21-24, 2004.
  9. R. Patnaik, S.Y. Chaudhari and S.K. Patnaik: effects of Anticonvulsant Semi-Carbazone 2,3,4 and Clobazam on GABA levels in Different regions of Rat Brain: 70th Ann. Meet Soc. Biol. Chem. (India), Hyderabad, Dec 27-29, 2001.
  10. S.K. Upadhya, R. Patnaik and R.B. Mishra: Study of Cognitive Component in Nerve Membrane Model, Proc. Symp. On recent Trends in Membr. Transp., pp 58, 1998.
  11. R. Patnaik and R.P. Tewari: Alpha EEG Biofed Back Training. Proc. 6th Natl. Conf. On Biomechanics, pp 274-276, 1998.
  12. R.P. Tewari, R. Patnaik and R.B. Mishar: Neuro Fuzzy Control of an Artificial Lower Limb. Proc. Natl. Conf. Biomed. Engg., pp 52-53, 1998.
  13. R. Patnaik and P.K Dey: Increased Blood Brain Barrier Permeabuility following Morphine Withdrawal in Rats. Proc. XXXI Ann. Conf. Assoc. Pharmacol. & Physiol of India, 1985.
Sponsored Research Projects undertaken as Principal Investigator (PI)/ Co-Investigator
 
S.N. Period Funding Agency Title of Project Amount of Grant PI/Co-Investigator
1. 2017 DIC, IIT BHU and BHU Design and development of a small hypobaric chamber for rodent 1,50,000 PI
2 2016 IRP (R&D), IIT BHU Stroke and Neuroprotection 15,00,000/
 
 
PI
3 2011-2015 Swedish Medical Research Council Molecular mechanism of blood-brain barrier permeability and cell injury in CNS trauma and neuroprotection 1.5m SEK/year Co-Investigator
4 2011-2014   Study on Radio-Frequency heating effects on the CNS: Reginal changes in brain metabolism and brain pathology and corrective measures 360k USD/year Co-Investigator
5 2010-2013   CNS Pathology and repair following substance abuse, Exploration of new therapeutic measures including nano-drug delivery 600k USD/year Co-Investigator
6 2011-2013   Role of cytoskeleton in Neurodegeneration and Neurorepair 900k USD/year Co-Investigator

Patent
 

S.N. Year Title International/National Status
1. 2011 Hearing aid along with wirless doorbell vibrator system and electronic torch light facility National Filed in 28/06/2011
Published in 13/07/2012

University Teaching and Administrative Responsibilities:

  1. Administrative Warden, I.T., Girls Hostel (1988-97)
  2. Guided Technex
  3. Chairman, Dramatics
  4. Flying Squad BHU Examination
  5. Member of National Bureau of Accreditation
  6. Expert for Project Evaluation Committee, UGC
  7. Convener DPGC - 2015- 16
  8. Chairman DFAC  - 2016-17

 
Member University level:

  • Animal Ethics Committee, IMS, Banaras Hindu University – 2015-16
  • Library Committee, IIT (BHU), Varanasi – 2015-16
  • Syllabus evaluation committee, NEHU, Shillong -- 

 
 Membership of the Societies and Affiliations:

  1. Member, FICCI National Committee on Science, Technology & Innovation
  2. SFN (Society for Neuroscience)
  3. IBRO (International Brain Research Organization)
  4. Life Member, Indian Academy of Neurosciences
  5. IBNS (International Behavioral   Neuroscience Society)
  6. APS (American Physiological Society)
  7. BNA (British Neuroscience Association)
  8. FENS (Federation of European Neuroscience Societies)

 
Editorial Duties

 
Reviewer:

  • Scientific Reports – Nature; Brain Research – Elsevier; Biomedicine & Pharmacotherapy- Elsevier; Proceedings of the National Academy of Sciences; BMC Neuroscience; Phytomedicine; Neurology and Therapy; BMC Complementary & Alternative Medicine; GENE; Biomedicine & Pharmacotherapy; Journal of Biological Engineering Research and Review; International Journal of Research in Engineering and Technology; International Journal of Biosensors & Bioelectronics

 
Distinctions/Prizes/Awards/Medals/Honours, etc.:

  1. Rashtriya Gaurav Award (2014)
  2. Best Citizen of India Award (2014)
  3. Rajiv Gandhi Excellence Awards (2014)
  4. National Award 2011 (by Department of Science and Technology, Govt. of India) for Low Cost Multi-use Hearing Aid.
  5. Saraswati Samman (2010)
  6. BHU Prize for standing first in B.Sc. (Hons.)
  7. BHU Scholarship for standing first in Diploma in Music
  8. Merit Scholarship of DGHS, Govt. of India, during Ph. D. Course
  9. Distinction in Physics (B.Sc. I), Chemistry (B.Sc. Hons.), Biochemistry (M. Sc.)
Ph.D. Students
 
S.N. Name of Student Year/Status Title of Thesis
1. Dr. Ravi Prakash Tewari   1999/Completed “Three Dimensional Kinematic & Dynamic Analysis of Below Knee Lower Limb Model for Artificial Design & Control (Based on the Concepts of Robotics & Biomechanics).
2. Dr. Surendra Kr. Upadhya 2000/Completed
 
ECG- EMG Signal Interpretation & Detection by using Artificial Neural Network.
3. Dr. Shiru Sharma 2010/Completed Cerebral Autoregulation under Stress & Disease
4. Dr. Anand Kumar Pandey 2011/Completed Hypoxia induced oxidative stress and Its Prevention- A study based on SPECT-Imaging
5. Dr. Pallab Bhattacharya 2012/Completed Focal Cerebral Ischemia and its Neuroprotection by Piroxicam
6. Dr. Sudip Paul 2016/Completed Electrophysiological Signal Analysis during Stroke in animal model
7 Mr. Gaurav Kumar 2014/Continuing Neuroprotection and Neurodegenerative Diseases
8 Sumedha Mukherjee 2014/Continuing Molecular Biology of Neurological Disorders and Neuroprotection
9 Chandrakant Tekam 2017/Continuing Will be decided during SOTA
10 Alok Tiwari 2017/Continuing Will be decided during SOTA
 

 
           

M. Tech./IDD Students
 
S.N. Name of Student Year Title of Thesis
1. Mr. Raj Kumar Roy 1994/Completed A study of Electromechanical properties of Natural Teeth in search of suitable Dental Implant materials
2. Mr. Khushvant Singh 1995/Completed Computerized Diagnostic guidelines for Jaundice.
  Mr. Rama Kant Singh 1995/Completed Coronary Angioplasty reporting system
3. Mr. Prem Narayan 1996/Completed A project report on Electrical safety in Biomedical equipments.
4. Mr. Kamalendra Kr. Singh 1997/Completed Neural network based ECG Interpretation.
5. Mr. Manoj Kumar Patel 2000/Completed A Biochemical study of Sach Foot
6. Mr. Raj Baboo 2001/Completed An acoustic model of Respiratory tract.
7. Mr. Prashant Gupta 2001/Completed Zero order predictor and wavelet packet based compression of single lead ECG.
8. Mr. R. Sampathi 2002/Completed Heat Transfer analysis during surgery
9. Mr. Anuj Kumar 2003/Completed Modification of Ultrasound B-Scan mode images using segmentation.
10. Mr. Vijay Kr. Singh 2003/Completed Predication of Arrhythmia using ECG Signal.
 
11. Mr. Ranjan Das 2004/Completed Design & Development of Polycentric Prosthetic Knee for Endoskeletal Transfemoral Prosthesis.
12 Mr. Kapil Kr. Agarwal 2005/Completed Detection of Micro-Calcifications in Mammograms.
13 Mr. S. Patra 2007/Completed Microcontroller based remote Electro Therapy programmable.
14 Mr. Shivnarayan Patida 2008/Completed PC based Phonocardiography.
15 Mr. Sudip Paul 2009/Completed Design of Low cost multi-use hearing aids
16 Mr. Arpit Sharma 2009/Completed Design of Electro magneto therapy unit for rat
17 Mr. Dishank Gupta 2011/Completed  
18 Ms. Archana Gupta 2011/Completed Effect of Electromagnetotherapy in Depression
19 Ms. Rupsha Mukhopadhyay 2011/Completed Effect of Electromagnetotherapy in Cerebral Ischemia
20 Mr. Uma Shanker Yadav 2015/Completed A Multifunctional Smart Hospital/Home Caregiver Bed for Bedridden people based on Android Application
21 Mr. Manoj Kumar Maurya 2016/Completed Impedence Analysis and Disease Diagnosis
22 Vikram Singh Meena 2017/continuing Designing a heartbeat monitoring system
23 Hemendra 2017/Completed Designing of the circuit for robotic arm
24 Kunwar Akhilendra Pratap Singh 2017/Completed Programming for the robotic arm
25 Abhinav DRP 2017/Completed Analysis of effect of thyroxin in memory impairment by using fear conditioning as a tool
26 Bhawna Bheermani 2017/continuing Neuroprotective role of progesterone
27 Alok Ranjan 2017/continuing Designing of Hypobaric Chamber
28 Ravi Krishnan 2017/continuing  
29 Rishabh Kesharwani 2017/continuing  
 

Address for correspondence:

Prof. Ranjana Patnaik
Electrophysiology Lab
School of Biomedical Engineering,
Institute of Technology, (Banaras Hindu University)           
Varanasi- 221005 (U.P)

Mobile: +91-542-2369525 (Res.); +91-9453984462 / +91-9336606824(Work)
E-Mail: rpatnaik.bme@iitbhu.ac.inranjanaswaraj@yahoo.com

Scientific Link:
 

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Electrophysiology Lab

(Neurological disorders and Neuroprotection Research Unit)

Major Facilities:
Non-invasive Blood Pressure Monitor (ADinstrument); Laser Doppler Blood Flow Meter(ADinstrument); Tissue oxygen Monitor (Oxford Optronix); HPLC-ECD; RotaRod; Ultrasound Probe Sonicator; -200C Refrigerator; Stereotactic Device with surgical table; Polyrite-D for EEG, ECG and EMG; EMF generator.

Minor Facilities: 
Centrifuge; Electronic Weighing Balance; Water Bath; Incubator; Oven; Bone Driller; Tissue Homogeniser; Refrigerator; Digital Sonicator; Double Distallation Unit; Liquid Nitrogen Container; Magnetic Stirrer; Vortex, pH meter; Heating Mantle.

Major Thrust Area:

  • Rodent Model Development: Middle Cerebral Artery Occlusion; Bilateral Common Carotid Artery Occlusion; Stress; Wound Healing etc.
  • Neuroprotection
  • In silico Drug Designing