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Dr. Nira Misra
School of Biomedical Engineering IIT BHU
Area of Interest: 
BIomaterials, Nanocomposites

Dr. Nira Misra, Ph.D.,
School of Biomedical Engineering,
Indian Institute of Technology (Banaras Hindu University)
E.mail : nmishra.bme@iitbhu.ac.in

Ph.D on “Synthesis and Characterization of Polymers With functional end groups”, IACS, Jadavpur, Kolkata
Specialization : Polymer Chemistry
M.Sc in Chemistry from Calcutta University
B.Sc (Honours) in Chemistry from Calcutta University

Jan 2011- Present Professor, School of Biomedical Engg, IIT(BHU), Varanasi
Jul’1998 – Dec’2010 Associate Professor, School of Biomedical Engg, IIT(BHU), Varanasi
Mar’1990 Jul’1998 Senior Lecturer, School of Biomedical Engg, IIT(BHU), Varanasi
Mar’1985 – Feb’ 1990 Lecturer, School of Biomedical Engg, IIT(BHU), Varanasi
1982 – 1985 Post-Doctoral Research Fellow at IACS, Jadavpur Kolkata
  • Synthesis of biodegradable amphiphillic polymers
  • Preparation of drug loaded micelles and their drug release phenomena
  • Fabrication of 3D scaffolds and their Tissue Engineering applications
  • Hybrid natural and synthetic polymer based hydrogels and their would healing application
  • Preparation of layered double hydroxides (LDH) and their reinforcement on commercial bone cement
  • Synthesis of porous silica nanoparticles and their reinforcement on various polymers to improve their mechanical property
  • Metal nanoparticles impregnated polymeric matrix for humidity sensing
Functional polymers
  • Modification of poly(vinyl chloride) (PVC) to improve the biocompatibility
  • Modification of poly(vinyl alcohol) (PVA)


  1. C.K. Balavigneswaran, S.K. Mahto, A.K. Mahanto, R. Singh, M. R. Vijayakumar, B. Ray, P. Maiti, N. Misra. Cell Proliferation mediated by Mechanical Property of gelatin grafted poly(D,L-Lactide) Three dimensional scaffolds. Journal of colloidal and surfaces B: biointerface (Revision).
  2. C.K. Balavigneswaran, A. Prabhakar, S Poddar, S Senapati, S Sellamuthu, V Rao, SK Singh, Ray B, Maiti P, Mahto SK, N. Misra. Inhibition of the formation of amyloid β-protein fibrils using synthesized gelatin grafted star shaped poly(D,L-Lactide). (Under preparation).
  3. C.K. Balavigneswaran, V Ramya, AK Mahanta, B Kadalmani, B Ray, P Maiti, SK Mahto, N. Misra. Engineering liver tissue spheroids using hybrid silica-gelatin grafted poly(D,L-Lactide) three dimensional scaffolds. (Under preparation).
  4. C.K. Balavigneswaran, V Ramya, G. Kapusetti, Ray B, Maiti P, SK Mahto, N. Misra.  Hybrid silica-gelatin grafted poly(D,L-Lactide) as Bioprinting ink. (Under preparation).
  5. S. Jaiswal, G. Kapusetti, A.K. Ray , N. Misra. Effect of Mangiferin on Fenton’s initiated aqueous polymerization of methyl methacrylate..  Polymer Bulletin. (Under review).
  7. S Singh, K Mitra, R Singh, A Kumari, SK SenGupta, N Misra, P Maiti, B Ray. Colorimetric Detection of Hydrogen Peroxide and Glucose using Brominated Graphene. Analytical Methods, 2017, 9, 6675–6681
  8. R. Sharma, G. Kapusetti, SY Bhong, P Roy, SK Singh, S Singh, C.K. Balavigneswaran, KK Mahto,  B. Ray, P. Maiti, N.  Misra, Osteoconductive Amine-Functionalized Graphene-Poly(methyl methacrylate) Bone Cement Composite with Controlled Exothermic Polymerization. Bioconjugate chemistry, 2017, 28(9):2254-2265. [I.F = 4.886]
  9. C.K. Balavigneswaran, S.K. Mahto, S. Bano, A.K. Mahanto, M. Ganguli, B. Ray, P. Maiti, N. Misra. Tailored Chemical Properties of 4 arm star shaped poly(D,L-Lactide) as Cell Adhesive Three-Dimensional Scaffolds. Bioconjugate chemistry 2017, 28, 1236 −1250. [I.F = 4.886]
  10. S. Singh, K. Mitra, A. Shukla, R. Singh, R. K. Gundampati, N. Misra, P. Maiti, B. Ray. Brominated Graphene as Mimetic Peroxidase for Sulfide Ion Recognition. Analytical chemistry, 2017, 89 (1), 783–791 [I.F = 5.886


  1. M.R. Vijayakumar, K.V. Yellappa, C.K. Balavigneswaran, S.K. Mahto, N. Misra, M.S. Muthu, S. Singh. Pharmacokinetics, biodistribution, invitro cytotoxicity and biocompatibility of Vitamin E TPGS coated trans resveratol liposomes. Journal of colloidal and surfaces B: biointerface, 2016, 145, 479-491 [I.F = 4.2
  2. N.K. Vishwakarma, V. K.Patel, R.K.Gundampati, S.L.Mudavath, K. Ramesh, K. K. Jana, P. K. Dutta, P.Maiti, N. Misra, M. V. Jagannadham, S.Sundar, B. Ray. Galactosylated Chitosan for Enhanced and Efficient Antimicrobialand Antileishmanial Activities: A Novel Approach.., Asian Chitin Journal, 2016.
  3. V.K. Patel, N. K.Vishwakarma, S. Singh, K.Mitra, K. Ramesh, N. Misra, B. Ray. Synthesis of Fluorescence Poly(N-Vinylpyrrolidone) via Click Chemistry Using Azide-terminated Xanthate Mediator (S)-2-(4-azidobutyl propionate)-(O-ethyl xanthate). International Journal of Polymeric Materials,2016, 65 (6), 269-76, .[I.F. = 3.53] 
  4. K. Ramesh, S. Singh, K. Mitra, D. Chattopadhyay, N. Misra, Biswajit Ray. Self-assembly of Novel Poly(D,L-Lactide-co-Glycolide)-b-Poly(N-Vinylpyrrolidone) (PLGA-b-PNVP) Amphiphilic Diblock Copolymers. Colloid Polym. Sci., 2016, 294, 399–407.[I.F. = 1.89] 
  5. K. Ramesh, R.k. Gundapati, K. Mitra, S. Singh, A. Shukla, M. V Jaganndham, D. Chattopadhyay, N. Misra, B. Ray. Self-Assembly, DOX-loading and Antibacterial Activity of Well-defined ABA-type Amphiphilic Poly(N-vinyl pyrrolidone)-b-Poly(D,L-lactide)-b-Poly(N-vinylpyrrolidone) Triblock Copolymers. RSC Advances. 2016, 6, 25864-25876 [I.F. = 3.82] 


  1. Monika, S. K. Mahto, S. Das, A. Ranjan, S. K. Singh, P. Roy, N. Misra. Chemical modification of poly(vinyl chloride) for blood and cellular biocompatibility. RSC Advances, 2015, 5, (56), 45231-45238, [I.F. = 3.82] 
  2. S. K. Hira, K. Ramesh, U. Gupta, K. Mitra, N. Misra, B. Ray, P.P. Manna. Methotrexate-Loaded Four-Arm Star Amphiphilic Block Copolymer Elicits CD8+T cell Response against a Highly Aggressive and Metastatic Experimental Lymphoma. ACS Appl. Mater. Interfaces,2015,7, 20021-20033.[I.F. = 7.2] 
  3. C.S. Biswas, K. Mitra, S. Singh, K. Ramesh, N. Misra, B. Maiti, A. K. Panda, P. Maiti, M. Kamigaito, Y. Okamoto, B. Ray. Study of the Effect of Isotacticity on Some Physical Properties of Poly(N-isopropylacrylamide). Colloid and polymer science, 2015, 293, 1749-1757.[I.F. = 1.89] 
  4. S. Jaiswal, K. Ramesh, G. Kapusetti, A. K. Ray, B. Ray, N. Misra. Mangiferin as Chain Transfer Agent: Effect on the Molecular Weight Poly(methylmethacrylate) and Polystyrene. Polymer Bulletin,2015, 72, 1407-1416.[I.F. = 1.40] 
  5. N.K. Vishwakarma, V.K. Patel, S.K. Hira, K.  Ramesh, P. Srivastava, K. Mitra, S. Singh, D. Chattopadhyay, P. Maiti, N. Misra, P.P.  Manna, B. Ray.Tadpole-shaped β-Cyclodextrin-tagged Poly(N-Vinylpyrroli done):  Synthesis, Characterization and Studies of Its Complexation with Phenolphthalein and Anti-Tumor Activities. RSC Adv., 2015, 5, 15547–15558.[I.F. = 3.82] 
  6. S. Singh, R. K. Gundampati, K. Mitra, K. Ramesh, M.V. Jaganaddam, N. Misra, B. Ray. Enhanced Catalytic and Antibacterial Activities of Silver Nanoparticles Immobilized on Poly(N-vinyl pyrrolidone)-Grafted Graphene Oxide.. RSC Adv., 2015, 5, 81994-82004.[I.F. = 3.82


  1. Monika, S.K. Singh and N. Misra. Chemical Modification of Poly(vinyl chloride) by thiourea: Influence of Surface Characteristics. Advanced Science, Engineering and Medicine,  6 (11), 1167-1170(4), 2014. 
  2. G. Kapusetti, Monika, A.K.Ray,  N. Misra.Thromboresistance of functionalized poly (methyl methacrylate): The effect of surface polarity. Bulletin of Material Science, 2014, 38, 3,  769–772 [I.F. = 0.870]
  3. G. Kapusetti, N. Misra, V. Singh, S. Srivastava, P. Roy, K. Danad, P. Maiti, Bone cement based nanohybrid as a super biomaterial for bone healing. Journal Material Chemistry B, 2014, 2, 3984-3997[I.F. = 4.726] 


  1. A. K. Mishra, K. Ramesh, T. K. Paira, D. N. Srivastava, T. K. Mandal, N. Misra, B. Ray. Synthesis and self-assembly properties of well-defined four-arm star poly(ε-caprolactone)-b-   poly(N-vinylpyrrolidone) amphiphilic block copolymers. Polymer Bulletin, 2013, 70, 3201–3220.[I.F. = 1.4
  2. G. Kapusetti, R. R. Mishra, S. Srivastava, N. Misra, V. Singh, P. Roy, S. K. Singh, C. Chakraborty, S. Malik, P. Maiti. Layered double hydroxide induced advancement in joint prosthesis using bone cement: the  effect of metal substitution Journal of Material Chemistry B, 1, 2275-88, 2013.[IF.= 4.726] 


  1. K. Ramesh, A. K. Mishra, V. K. Patel, N. K. Vishwakarma, C. S. Biswas, T. Kumar, P.T. K. Mandal, P. Maiti, N. Misra, B. Ray. Synthesis of well-defined amphiphilic poly(D,L-lactide)-bpoly(N-vinylpyrrolidone) block copolymers using ROP and xanthate-mediated RAFT polymerization, Polymer, 2012, 53 (25), 5743-52. [I.F. = 3.78] 
  2. N. Misra, A. Sarkar, A. Srinivas, G. Kapusetti. Study of Blood Viscosity at Low Shear Rate and Its Flowthrough Viscoelastic Tubes and Ducts   Indian Journal of Physics, 2012 86 (2), 89-96. [I.F.= 1.786]. 
  3. G. Kapusetti, N. Misra, V. Singh, R. K. Kushwaha, P. Maiti. Bone cement/layered double hydroxide nanocomposites as potential biomaterials for joint implant J Biomed Mater Res  Part A, 2012, 100A:3363–3373..  [I.F. = 3.263] (Citation-13)


  1. N. Misra, H. S. Panda, G. Kapusetti, S.Jaiswal Modification of PVC Film and study the effect of Glass transition temperature and Biocompatibility, Journal of  Polymer Materials, 2011, 28(2); 141-150.[I.F. = 0.4] 
  2. N. Misra, H.S. Panda, G. Kapusetti, S. Jaiswal, S. Bhattacharya Physical and Conductivity properties of Poly (vinyl chloride) Ionomers.. Indian Journal of Physics, 2011, 85(2);271-279. [I.F.= 1.786] 
  3. N. Misra, S. Bharti, G. Kapusetti, D.K. Upadhyay, S. Jaiswal, H.S.Panda,  R Prakash Polyaniline-Poly (vinyl alcohol) IPN-Composite Prepared from Potassium Dichromate embeddedPVA Film: A Material for Humidity Sensing Application..  Indian Journal of Physics, 2011, 85(5); 703-712. [I.F.= 1.786]  
  4. N. Misra, G. Kapusetti, S. Jaiswal ,P. Maiti Toughening of bone cement using nanoparticle: The effect of solvent., Journal of Applied Polymer Science,2011, 121; 1203–1213. [I.F. = 1.24] 
  5. N.  Misra, M. Sinha, R.M. Banik Microbial Transformation of Functionality of Polymer Latex by UstilogoMaydis.. Journal of Polymer Materials, 28(1), 1-3. 2011. [I.F. = 0.4]
  6. N. Misra, G. Kapusetti, D.K Pattanayak,Fabrication and characterization of epoxy/silica functionally graded composite material. A. Kumar. Indian Journal of Physics, 2011, 85(9); 1393-1404. [I.F.= 1.786]. 

Prior 2011

  1. S. K. Sengupta., U. Sandhir, and N. Misra, A Study of Polymerization of Acrylamide at Plasma/Liquid Interface by Anodic Contact Glow Discharge Electrolysis in Aqueous Media J. of Ploym. Sci.,Part-A Polym. Chem. 2001, Edition, 39, 1584. 
  2. S. Ghoshal, G. Rao and V. Sarvanan & N. Misra and D. Rana, A Plausible Chemical Mechanism of the Bioactivities of Mangiferin, Indian J. of Chemistry, 35B, 561, 1996. (Citation-41)
  3. S. Ghoshal, S. Lata & Y. Kumar and B. Gaur & N. Misra. Interaction of Shilajit With Biogenic Free Radicals, Indian J. of Chemistry, 1995, 34B, 596, . 
  4. N. Misra and B. M. Mandal. Sulfate Functionality of Polystyrene prepared by Soapless Emulsion Polymerization Method in tert-Butyl Alcohol and Water Media. J of Ploym. Sci., Polymer Letters, 1985, Edition, 23, 63. 
  5. N. Misra and B. M. Mandal, Anomalous GPC elution of Polymers Containing lonic End Functions: GPC of polystyrene prepared by K2 S2 O8 Initiator. Makromol. Chem., Rapid Commun, 5, 471, 1984. 
  6. N. Misra and B. M. Mandal Persulfate-Initiated Polystyrene: Aggregation of Potassium α,ω- Polystyrene Sulfate in Toluene, Macromolecules. 1984, 17 , 495. 
  7. N. Misra, A.K. Banthia and B.M. Mandal. Intermolecular Association of Polymers Through Functional End-Groups Sulphate and Sulphonate End-Groups. Europe. Polym. J. 1979 , Vol. 15., p. 943,


Ph.D Scholars (Ongoing)
After completion of my B.Tech in Biotechnology and M.Tech in Nanoscience and Technology I Joined Prof. Nira Misra’s Polymer Engineering Lab as a Research scholar in 2013. As a part of my Ph.D, I am developing protein grafted polyester based three dimensional (3D) scaffolds for Biomedical applications.
I use physico chemical techniques to characterize the synthesized polymers and various cellular and biochemical assays to validate the biocompatibility and the functionality of the cells
 E.mail: ckbalavigneswaran.rs.bme13@iitbhu.ac.in
  Kaushal Kumar Mahato
I joined in Polymer Engineering lab in 2013 after my completion of M.Tech in Biomedical Engineering and 2 years of research experience. I am working on developing hybrid hydrogels for Biomedical applications

E.mail: kkmahato.rs.bme13@iitbhu.ac.in 

  Dr. Monika Singh (2010-2015)
Thesis Title : Evaluation of Polymeric Ionomers Composite and Its Exposure with Mouse Mesenchymal Stem Cells

E.mail: monika.rs.bme10@itbhu.ac.in 

  Dr. K. Ramesh (2010-2014)
Thesis: Synthesis and Characterization of Poly(D,L-Lactide) based amphiphilic block copolymers for Drug Delivery

E.mail: kramesh.chem@gmail.com 

Present Position: Post doc scientist at Pukyong National University, Busan 48513, Republic of Korea.

  Dr. Shilpa Jaiswal (2006-2013)
Thesis: Polymer based Magniferin Delivery systems


  Dr. Govinda Kapusetti (2009-2013)
Thesis: Bone Cement Nanocomposites for Biomedical Applications
E.mail: govindphysics@gmail.com 

Present Position: Assistant Professor, NIPER, Ahmedabad

Dr. Nira Misra, Ph.D.,
School of Biomedical Engineering,
Indian Institute of Technology (Banaras Hindu University)
E.mail : nmishra.bme@iitbhu.ac.in
Mobile No.: +919452569747