manojk.che's picture
Dr. Manoj Kumar
Assistant Professor
Department of Chemical Engineering IIT BHU.
manojk.che@iitbhu.ac.in
+91 8283839972
Area of Interest: 
Interfacial Science and Technology, Mass transport in Biological Systems, Thin-films, Biophotonics, Photocatalysis, Photovolatics,Non-Linear Optical Nanomaterials, Optical Nanomaterial Synthesis and Applications, Nucleic Acid based Technologies

  • Postdoctoral Fellow (2010-2013) Miller Medical School, Miami, FL, USA
  • Postdocoral Fellow (2009-2010) Indiana University Purdue University, Indianapolis, IN, USA
  • Ph.D. (2009) New Mexico Institute of Mining and Technology, NM, USA
  • B.E. (1997) S.I.T. Tumkur

 

  • Langmuir Award by NMT (2009), USA
  • Best Poster Award (2008), by ACS Local Chapter, USA

 

  • DST Nano Mission (FY2016-19)- INR 51 Lacks:Development & Evaluation of Infrared Nanoparticles for Cellular-Wide Sensitive E-field Mapping 
  • IIT (BHU) Startup (FY2015)- 10 Lacks
  • CEERD (FY2017-18)- 10 Lacks: Intelligent Dye Sensitized Solar Cells
  • IRP (FY 2018-19)- 15 Lacks:
Group Vision

Transformation of material from bulk to nano size results in modified electrical, optical, magnetic and chemical properties. These properties can used to solve problems in the area of health, energy, security and environment. Our group focuses to solve some of the intricate problems in these areas by employing thermodynamic and kinetic control during synthetic process to obtain nanomaterials having reproducible size, morphology and surface properties. Further, our group is trying to develop an insight into the mass transport problems of the nanosystems into biological systems using mathematical and experimental tools and develop them for its application in the above cited areas. Through our understanding in the area of Chemical Engineering, Chemistry, Physics and Mathematics, we hope to design new nanosystem platforms for the detection of communicable and non-communicable diseases, develop sensitive and selective sensors for arsenite, mercury and heavy metal detection, and design new catalyst for various types of reactions and energy generation. We hope to utilize our understanding to cater affordable solutions in the above cited areas to all sectors of population locally and internationally.

Design and Development of Non-Linear Optical Nanomaterials

Non-linear optical nanomaterials based on NaYF4 host lattice are one of the most efficient converters of multiple low energy photons to one high energy photons. The emission intensity of these materials quadratically depends on the excitation intensity and hence produces highly focused visible emission. Upconverting nanomaterial, display near infrared excitation, narrow emission and excitation band, environment invariant emissions, and no photobleaching, making them suitable for its application in the area of nanomedicine, imaging, biosensing, photocatalysis, energy generation, displays and opto-bi-functional devices. Despite great potential, their applicability remains limited due to their restricted color availability, small extinction coefficient and low quantum yield. Our group focuses on the development of new synthetic modalities that are based on thermodynamic and kinetic control and evaluate effect of the control mechanism on the size, morphology, optical, magnetic and electrical properties and quantum yield. We hope to develop new synthetic process yielding high quantum yield, multicolor, magnetically active and monodisperse upconverting nanomaterials and put them to use in the area of energy generation, photocatalysis, heavy metal and arsenic detection.

New Material and Devices

Ubiquitous arsenic presences in the earth crust and ground water has impending effect on global health, almost affecting 144 million population. Despite these issues, development of new optical materials that can facilitate simple, easy, reliable, sensitive and selective detection are few. Our research group has been able to successfully develop new optically active materials that can detect arsenite (As3+) at 12.5 parts per trillion levels with high accuracy (99% spike recovery).The material utilizes upconverting host lattice deposited over the solid substrate. We envision to use these substarte in conjunction with minaturized optical system as pocket carrying devices.
 
 

 

PUBLICATIONS (2007-2013)
Total publications: 09, total Citations: ~700; total impact Factor: 54; h-index 8
 
9. A targeted and adjuvanted nanocarrier lowers the effective dose of liposomal amphoteracin B and enhances adaptive immunity in murine cutaneous leishmaniasis. Daftarian, P; Stone, G; Kovalski, L; Kumar, M; Vosoughi, A; Urbieta, M; Blackwelder, P; Dikici, E; Serafini, P; Duffort, S; Boodoo, R; Rodríguez-Cortés, A; Lemmon, V; Deo, S; Alberola, J; Perez, V; Daunert, S; Agar, The Journal of Infectious Disease 2013, 208 (11): 1914-22. JIF 5.94 (Citations 3).

8. Solution-phase detection of dual microRNA biomarkers in serum. D. Broyles, Kyle Cissel, M. Kumar, S.K. Deo, Analytical Bioanalytical Chemistry 2012,402, 543-545, JIF 3.58 (Citations 6). 
7. A rapid sensitive and selective bioluminescent resonance energy transfer (BRET)-based nucleic acid sensing system. M. Kumar, D. Zhang, D. Broyles, S.K. Deo, Biosensor & Bioelectronics. 2011, 30, 133-139, JIF 6.45 (Citations 12). 
6. Highly sensitive and selective label-free optical detection of mercuric ions using photon upconverting nanoparticles.  M. Kumar, P. Zhang, Biosensors & Bioelectronics 2010, 25, 2431-2435, JIF 6.45 (Citations 44). 
5. Highly sensitive and selective label-free optical detection of DNA hybridization based on photon upconverting nanoparticles. M. Kumar, P. Zhang, Langmuir2009, 25, 11, JIF 4.3 (Citations 50). 
4. Synthesis, characterization and biosensing application of photon upconverting nanoparticles.  M. Kumar, P. Zhang, Proc. SPIE2009, 7188, 71880F. JIF 0.89 (Citations 2). 
3. Highly sensitive and selective oligonucleotide sensor for sickle cell disease gene using photon upconverting nanoparticles.  M. Kumar, Y. Guo, P. Zhang. Biosensors & Bioelectronics 2009, 24,1522-1526, JIF 6.45  (Citations 43). 
2. Nanoparticles-based photosensitizers under CW infrared excitation.  Y. Guo, M. Kumar, P. Zhang. Chemistry of Materials 2007, 19 (25), 6071, JIF 8.5 (Citations 30). 
1. Versatile photosensitizers for photodynamic therapy at infrared excitation.  P. Zhang, W. Steelant, M. Kumar, M. Scholfield. Journal of American Chemical Society 2007,129 (15), 526-527, JIF 11.4 (Citations 324 ).

INVITED TALKS
 
3. Luminescent Nanoscale Materials for Biomedical Application-Breaking Away from Convention, A Short term Course “Smart Materials and Structures: Recent Trends in Industrial Application”, held from 4th- 11th Sept 2017, Department of Mechanical Engineering, IIT (BHU) Varanasi-221005, Manoj Kumar, School of Biomedical Engineering & Department of Chemical Engineering, IIT (BHU).
 
2. Thin-film Deposition of Upconverting Materials on solid substrates Using Low Temperature, Simple, Inexpensive Facile Hydrothermal Method for Biosensing Applications, International Conference on Nanomedicine and Tissue Engineering, held on 12th -14th August 2016, at Mahatma Gandhi University, Kottayam, Kerala.  Suman Duhan, Sudhir Ranajan, Manoj Kumar, Department of Chemical Engineering & School of Biomedical Engineering, IIT (BHU).
 
1. Design & development of nano-upconverting transducers for sickle cell anemia detection, International Conference on Material Science & Technology held on 1st – 4thMarch 2016, Delhi University (North Campus). Suman Duhan (Ph.D. Scholar), Manoj Kumar, Department of Chemical Engineering, IIT (BHU).