Dr. Prabhat Tripathi
MSc Chemistry Integrated under 5yr program, 2008-2013
Indian Institute of Technology (Indian School of Mines), Dhanbad, India
PhD Chemistry, 2014-2018, University of Massachusetts, Amherst
Thesis advisor: Prof. Murugappan Muthukumar
Thesis title: “Voltage-Driven Polyelectrolyte Complexation Inside a Nanopore”
Nov 2018 - Nov 2022 – Postdoctoral Research Associate, Department of Physics, Northeastern University (Boston), Postdoc advisor: Prof. Meni Wanunu
(A) Undergraduate Research Intern (Prof. Martin Gruebele’s Lab), 05/2012−07/2012 Department of Chemistry, University of Illinois at Urbana-Champaign, USA.
(B) Undergraduate Research Intern (Prof. Kyung Hyung Ahn’s Lab), 12/2010−01/2011 and 05/2011−07/2011, School of Chemical and Biological Engineering, Seoul National University, South Korea.
(C) Undergraduate Research Intern (Prof. Charles Pittman’s Lab), 06/2010−08/2010, Department of Chemistry, Mississippi State University, USA.
Our interests are in combining theory and single-molecule experiments to study a broad range of fundamental problems in physics, chemistry, and biology. A common theme in these single-molecule experiments is the implementation of the state-of-the-art solid-state nanopore (or biological nanopore) and single-channel electrical recordings to interrogate and manipulate complex molecular systems. The main advantage of these techniques is their ability to directly measure short-lived (< 1 microsecond) rare single-molecule events with very high accuracy without any requirement of chemical labeling. The outcome of these efforts will contribute to a deeper understanding of the correlation between protein function and its structural dynamics, for example, how proteins utilize their conformational fluctuation at different time scales to move across cellular compartments, how one can directly observe conformationally excited and hidden states of proteins, how conformational energy levels of a protein can be controlled by an external electric field, and the solar energy flow in large molecular complexes such as photosynthetic systems.
Chemical Kinetics and Photochemistry (CY101)
Quantum Chemistry (CHI 312/ CHI313)
Adsorption and Heterogeneous Catalysis (CHI 423)
Industrial Chemistry Practice Course (CHI 101)
Preparatory Chemistry Course (CHY-P-103)