Dr. Sushant Kumar Shrivastava

Professor
Department of Pharmaceutical Engineering and Technology
Email:
skshrivastava.phe@iitbhu.ac.in
Phone(s):
91-9452156527 , 91-542-6702725
Website:
Area of Interest:
Pharmaceutical Medicinal and Computational chemistry
  • B Pharm.: Dr. H S Gaur Vishwavidhyalaya, Sagar, MP
  • M Pharm.: Dr. H S Gaur Vishwavidhyalaya, Sagar, MP
  • PhD.: Devi Ahilya Vishwavidhyalaya, Indore, MP
  • Teaching: 27 years
  • Undergraduate:
    • Pharmaceutical Organic Chemistry II
    • Pharmaceutical Analysis
    • Pharmaceutical Biochemistry
    • Pharmaceutical Medicinal Chemistry I, II & III
    • Drug Design 
  • Postgraduate:
    • Chemistry of Synthetic Drugs
    • Drug Design
    • Advanced Medicinal Chemistry
  • PhD:
    • Advanced Pharmaceutical Chemistry
  • Rational Drug Design and Molecular Modeling
  • Synthetic Medicinal Chemistry
  • Inflammation, Alzheimer's disease, and cancer
  • UGC Research Project 37-52/2009(SR) “Synthesis and evaluation of Lamotrigine-Glutathione inducing amino acid conjugates to minimise hepatotoxicity: A Prodrug Approach” (11.0 lakhs)
  • IIT (BHU) sponsored research project entitled 25/03/2014 “Design, Synthesis and Evaluation of Some New Heterocyclic Compounds as Potential Hypoglycemic and Antimicrobial Agents” (15.0 Lakhs).
  • IIT (BHU) sponsored research project entitled 04/01/2016 “Design, synthesis, molecular modeling and evaluation of some novel heterocyclic compounds as potential anti-hypoglycemic agents”(Rs 13,20,374/-). 
  • IIT(BHU) Post Doctoral Fellowship- Ref. IIT (BHU)/ R&D/PDF/2015-16/4085/L dated 20-02-2016.
  • Mentor of Young Scientist- Mr. Piyoosh Sharma for the research funded project from Department of Health Research (DHR), Ministry of Health and Family Welfare, Govt. of India; HRD Fellowship – (Rs 45,12,000/-) for 3 years (2016-2019).
  • SERB-CRG sponsored research project entitled "Design and Development of potential multifunctional molecular hybrids for the treatment of Alzheimer’s disease"- (Rs. 28,28,600/-) for 3 years dated- Janurary 2022
  • ICMR-DHR sponsored reserch project entitled " Design and Development of Molecular Hybrids on a Multifunctional Framework for Regulating Cholinesterases, β-secretase 1, Amyloid-β, and Oxidative Stress Against Alzheimer’s Disease"- (Rs. 58,66,866/-) for 3 years dated- 14-12-2021-01-05-2025
  • IIT (BHU) challenge grant on title “Design, Synthesis, and Pharmacological Evaluation of some novel Heterocyclic compounds as multi-targeting agents in Alzheimer’s Disease therapy.” (Rs. 35,00,000/-) 2025 for 2 years- Ongoing

Total Publications: 124
Citations:
Citations: > 4079;                       h-index: 35;                 i-10 index: 81
(Source: Google Scholar https://scholar.google.co.in/citations?hl=en&user=o6lTDWIAAAAJ)

  • S. No.Author(s)TitleName of JournalVol.PageYearI.F.
    •  
    Aswathi C Narayanan, Hansal Kumar, Sushant Kumar Shrivastava, Jeyakumar Kandasamy, Sundaram SinghSynthesis of cinnamic esters and acids via palladium-catalyzed reactions of aryl diazonium salts and their biological evaluation.Organic & Biomolecular Chemistry24(8)1703-170820262.70
    •  
    Bhardwaj B,
    Vishwakarma SK,
    Singh A, Kumar H,
    Gajendra TA, Verma A,
    Krishnamurthy S,
    Davisson VJ,
    Shrivastava SK.
    Novel benzothiazole-based
    cholinesterase inhibitors with
    amyloid beta disaggregation and
    antioxidant activity against
    Alzheimer’s disease
    European Journal
    of Medicinal
    Chemistry
    29811804720255.9
    •  
    Siddiqui MA, Saraf P, Shrivastava SK, Penumaka SM, Mandal D, Saini R, Pathak A, Ramakrishna K, Krishnamurthy S.Discovery of platelet glycoprotein VI receptor antagonists and their neuroprotective activity: an in silico, in vitro, and in vivo study3 Biotech1535720252.9
    •  
    Verma A, Waiker DK, Gupta PS, Kumar M, Shrivastava SK.Bioisosterism: an approach to develop new anti-cancer agentsEuropean Journal of Medicinal Chemistry  1181665.9
    •  
    Tiwari AK, Jain D, Tiwari JK, Kishore S, Singh AK, Shrivastava SK, Khattri A.Deciphering oral cancer subtypes: Integrating differential gene expression and pathway analysis followed by non-negative matrix factorization transcription analysisOral Oncology Reports1410073520253.9
    •  
    Singh M, Karthikeyan C, Waiker DK, Tiwari A, Shrivastava SK, Sousa SF, Kiriwan D, Martins FG, Moorthy NS.Design, synthesis, and pharmacological evaluation of heteroaryl thiol-linked kojic acid derivatives as a novel class of acetylcholinesterase inhibitors for Alzheimer’s disease therapy3 Biotech1513420252.9
    •  
    Tiwari AK, Jain D, Nizamuddin S, Srivastava RS, Singh S, Shrivastava SK, Khattri A.Solute carrier family 2 members (SLC2A) as potential targets for the treatment of head and neck squamous cell carcinoma patientsHuman Gene4320136520253.6
    •  
    Poorvi Saraf, Prabhash Nath Tripathi, Manish Kumar Tripathi, Avanish Tripathi, Himanshu Verma, Digambar Kumar Waiker, Royana Singh, Sushant Kumar ShrivastavaNovel 5, 6-diphenyl-1, 2, 4-triazine-3-thiol derivatives as dual COX-2/5-LOX inhibitors devoid of cardiotoxicityBioorganic Chemistry12910614720225.3
    •  
    Sushant Kumar Shrivastava, Ojaswi Sinha, Munish Kumar, Digambar Kumar Waiker, Akash Verma, Prabhash Nath Tripathi, Bhagwati Bhardwaj, Poorvi SarafSynthesis, characterization, and biological evaluation of some novel ϒ-aminobutyric acid aminotransferase (GABA-AT) inhibitorsMedicinal Chemistry Research311594-161020222.351
    •  
    Urmilesh Singh, Laxmi, Prabhakar Singh, Ankit Kumar Singh, Sweksha Singh, Deepak Kumar, Sushant Kumar Shrivastava, Ravi Kumar AsthanaIn silico and in vitro evaluation of extract derived from Dunaliella salina, a halotolerant microalga for its antifungal and antibacterial activityJournal of Biomolecular Structure and Dynamics401-1520223.392
    •  
    Sushant K Shrivastava, Avhad Ashok Nivrutti, Bhagwati Bhardwaj, Digambar Kumar Waiker, Akash Verma, Prabhash Nath Tripathi, Manish Tripathi, Poorvi SarafDrug reposition-based design, synthesis, and biological evaluation of dual inhibitors of acetylcholinesterase and β-Secretase for treatment of Alzheimer's diseaseJournal of Molecular Structure126213297920223.841
    •  
    Wei Yu, Yiming Ma, Sushant K Shrivastava, Rakesh K Srivastava, Sharmila ShankarChronic alcohol exposure induces hepatocyte damage by inducing oxidative stress, SATB2 and stem cell‐like characteristics, and activating lipogenesisJournal of Cellular and Molecular Medicine262119-213120225.295
    •  
    Akash Verma, Digambar Kumar Waiker, Bhagwati Bhardwaj, Poorvi Saraf, Sushant K ShrivastavaThe molecular mechanism, targets, and novel molecules in the treatment of Alzheimer’s diseaseBioorganic Chemistry11910556220225.30
    •  
    Salunke Prashant Ramrao, Akash Verma, Digambar Kumar Waiker, Prabhash Nath Tripathi, Sushant Kumar ShrivastavaDesign, synthesis, and evaluation of some novel biphenyl imidazole derivatives for the treatment of Alzheimer's diseaseJournal of Molecular Structure124613115220213.841
    •  
    Kamta P Namdeo, Sushant K Shrivastava, Ramesh ChandraSynthesis of Some Glycine Nicotinates and in-vivo Evaluation of Anti-Convulsant Activity for their Brain specific Slow Release ActionINDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH55888-89320210.5
    •  
    Choube, P.K.,Tripathi, A.,Tripathi,M.K.,Seth,A.,Shrivastava,S.KDesign,synthesis and evaluation of N-benzylpyrrolidine and 1,3,4-oxadiazole as multitargeted hybrids for the treatmentof Alzhiemer’s DiseseBioorganic Chemistry11110492220214.8
    •  
    Singh,U,Singh,P.,Singh,A.K., Laxmi, Kumar,D, Tilak,R.,Shrivastava,S.K. and Asthana,R.Identification of antifungal and antibacterial biomolecules from a cyanobacterium, Artrospira platensisAlgal Research5410221520215.0
    •  
    Choubey,P.K., Tripathi,A., Sharma,P. and Shrivastava,S.KDesign,synthesis and multitargeted profiling of N-benzylpyrrolidine derivatives for the treatment of Alzheimer’s diseaseBioorganic and Medicinal Chemistry28 (22)11572120203.0
    •  
    Chikhale,R.V.,Gurav,S.S.,Patil,R.B., Sinha,S.K., Prasad,S.K., Shakya,A.,Shrivastava,S.K.,Gurav,N.S., Prasad,R.S.Sars-cov-2 host entry and replication inhibitors from Indian ginseng: an in-silico approachJournal of Biomolecular Structure and Dynamics 1-420204.98
    •  
    Lam,B.Q., Shrivastava,S.K., Shrivastava,A., Shankar,S., Srivastava,R.The impact of obesity and diabetes mellitus on pancreatic cancer:Molecular mechanism and clinical perspectivesJournal of Cellular and Molecular Medicine24 (14)7706-771620204.6
    •  
    Tripathi,M.K., Sharma,P., Tripathi,A., Tripathi,P.N., Srivastava,P.,Seth,A.  Shrivastava,S.K.Computational exploration and experimental validation to identify a dual inhibitor of cholinesterase and amyloid-beta for the treatment of Alzheimer’s diseaseJournal of Computer Aided Molecular Design34983-100220202.54
    •  
    Tripathi, A., Choubey, P.K., Sharma, P., Seth, A., Saraf, P., Shrivastava, S.K.Design, Synthesis, and Biological Evaluation of Ferulic Acid Based 1,3,4-Oxadiazole Hybrids as Multifunctional Therapeutics for the Treatment of Alzheimer’s DiseaseBioorganic Chemistry9510350620204.8
    •  
    Tripathi, A., Choubey, P.K., Sharma, P., Seth, A., Tripathi, M.K., Shrivastava, S.K.Design and Development of Multifunctional Hybrids of Ferulic Acid and 1,3,4-Oxadiazoles for the Treatment of Alzheimer’s DiseaseCurrent Trends in Biotechnology  and Pharmacy14 (1)81-962020-
    •  
    Tripathi, A., Choubey, P.K., Sharma, P., Seth, A., Tripathi, P.N., Tripathi, M.K., Prajapati, S.K., Krishnamurthy, S., Shrivastava, S.K.Design and development of molecular hybrids of 2-pyridylpiperazine and 5-phenyl-1,3,4-oxadiazoles as potential multifunctional agents to treat Alzheimer's diseaseEuropean Journal of Medicinal Chemistry18311170720195.57
    •  
    Sharma, P., Tripathi, A., Tripathi, P.N., Singh, S.S., Singh, S.P., Shrivastava, S.K.Novel Molecular Hybrids of N-Benzylpiperidine and 1,3,4-Oxadiazole as Multitargeted Therapeutics to Treat Alzheimer’s DiseaseACS Chemical Neuroscience104361-438420194.48
    •  
    Srivastava, P., Tripathi, P.N., Sharma, P., Shrivastava, S.K.Design, synthesis, and evaluation of novel N-(4-phenoxybenzyl)aniline derivatives targeting acetylcholinesterase, β-amyloid aggregation and oxidative stress to treat Alzheimer’s diseaseBioorganic & Medicinal Chemistry27 (16)3650-366220193.0
    •  
    Mishra, P., Sharma, P., Tripathi, P.N., Gupta, S.K., Srivastava, P., Seth, A., Tripathi, A., Krishnamurthy, S., Shrivastava, S.K.Design and Development of 1,3,4-Oxadiazole Derivatives as Potential Inhibitors of Acetylcholinesterase to Ameliorate Scopolamine-Induced Cognitive DysfunctionsBioorganic Chemistry8510302520194.8
    •  
    Tripathi, P.N., Srivastava, P, Sharma, P., Seth, A., Shrivastava, S.K.Design and development of novel N-(pyrimidin-2-yl)-1, 3, 4-oxadiazole hybrids to treat cognitive dysfunctionsBioorganic & Medicinal Chemistry27 (7)1327-134020193.0
    •  
    Sharma, P., Srivastava, P., Seth, A., Tripathi, P.N., Banerjee, A.G., Shrivastava, S.K.Comprehensive review of mechanisms of pathogenesis involved in Alzheimer’s disease and potential therapeutic strategiesProgress in Neurobiology17453-89201914.16
    •  
    Fu, J., Shrivastava, A., Shrivastava, S.K., Srivastava, R.K., Shankar, S.Triacetyl resveratrol upregulates miRNA‑200 and suppresses the Shh pathway in pancreatic cancer: A potential therapeutic agentInternational Journal of Oncology54 (4)1306-131620193.33
    •  
    Sharma, P., Tripathi, A., Tripathi, P.N., Prajapati, S.K., Seth, A., Tripathi, M.K., Srivastava, P., Tiwari, V., Krishnamurthy, S., Shrivastava, S.K.Design and development of multitarget-directed N-Benzylpiperidine analogs as potential candidates for the treatment of Alzheimer’s diseaseEuropean Journal of Medicinal Chemistry167510-52420195.57
    •  
    Tripathi, P.N., Srivastava, P., Sharma, P., Tripathi, M.K., Seth, A., Tripathi, A., Rai, S.N., Singh, S.P. Shrivastava, S.K.Biphenyl-3-oxo-1, 2, 4-triazine linked piperazine derivatives as potential cholinesterase inhibitors with anti-oxidant property to improve the learning and memoryBioorganic Chemistry8582-9620194.8
    •  
    Srivastava, P., Tripathi, P.N., Sharma, P., Rai, S.N., Singh, S.P., Srivastava, R.K., Shankar, S., Shrivastava, S.K.Design and development of some phenyl benzoxazole derivatives as a potent acetylcholinesterase inhibitor with antioxidant property to enhance learning and memoryEuropean Journal of Medicinal Chemistry163116-13520195.57
    •  
    Besan, M., Gautam, M.K., Shrivastava, S.K.Development of 1, 4-Naphthoquinones as Potential Epidermal Growth Factor Receptor Inhibitors For The Treatment of CancerCurrent Trends in Biotechnology and Pharmacy13 (3)283-3082019-
    •  
    Besan, M., Gautam, M.K., Shrivastava, S.K.Design, Synthesis, Cytotoxicity Evaluation, and Molecular Docking Studies of 1,3,4- Oxadiazole substituted 1,4-Naphthoquinone DerivativesCurrent Trends in Biotechnology and Pharmacy13 (3)243-2582019-
    •  
    Srivastava, P., Tripathi, P.N., Sharma, P.,  Shrivastava, S.K.Quantitive Structre Activity Relationship based Design, Synthesis, and Evaluation of Novel Diarylether derivatives as a potent Acetylcholinesterase inhibitor and Antioxidant to treat Cognitive dysfunctionsCurrent Trends in Biotechnology and Pharmacy13 (2)124-1452019-
    •  
    Shrivastava, S.K. et al.Design and development of novel p-aminobenzoic acid derivatives as potential cholinesterase inhibitors for the treatment of Alzheimer’s diseaseBioorganic Chemistry82211-22320194.8
    •  
    Singh, N.K., Garabadu, D., Sharma, P., Shrivastava, S.K. & Mishra, P.Anti-allergy and anti-tussive activity of Clitoria ternatea L. in experimental animals.Journal of Ethnopharmacology22415-2620182.98
    •  
    Shrivastava, S.K., Tripathi, P., Srivastava, P., Sharma, P., Tripathi, A., Seth, A., Tripathi, M.K.Synthesis, evaluation and docking studies of some 4-thiazolone derivatives as effective lipoxygenase inhibitors.Chemical Papers72 (11)2769-278320181.25
    •  
    Seth, A., Sharma, P., Tripathi, A., Choubey, P., Srivastava, P., Tripathi, P. & Shrivastava, S.K.Design, Synthesis, Evaluation and Computational Studies of Nipecotic Acid-Acetonaphthone Hybrids as Potential Antiepileptic Agents.Medicinal Chemistry14 (4)409-42620182.33
    •  
    Seth, A., Sharma, P.A., Tripathi, A., Choubey, P.K., Srivastava, P., Tripathi, P.N. & Shrivastava, S.K.Design, synthesis, evaluation and molecular modeling studies of some novel N-substituted piperidine-3-carboxylic acid derivatives as potential anticonvulsants.Medicinal Chemistry Research271206-122520181.27
    •  
    Shrivastava, S.K., Srivastava, P., Bandresh, R., Tripathi, P.N. & Tripathi, A.Design, synthesis, and biological evaluation of some novel indolizine derivatives as dual cyclooxygenase and lipoxygenase inhibitor for anti-inflammatory activity.Bioorganic & Medicinal Chemistry254424-443220173.0
    •  
    Kulshrestha, A., Das, N., Banerjee, A.G. & Shrivastava, S.K.Design, synthesis and pharmacological evaluation of some pyrazolopyrimidin-6 (7H)-ones and tricyclic 8-oxo-dihydrooxazolopyrazolopyrimidin-9-ium chloride derivatives.Arabian Journal of Chemistry10S3614-S36212017
     
    4.76
    •  
    Shrivastava, S.K., Srivastava, P., Upendra, T., Tripathi, P.N. & Sinha, S.K.Design, synthesis and evaluation of some N-methylenebenzenamine derivatives as selective acetylcholinesterase (AChE) inhibitor and antioxidant to enhance learning and memory.Bioorganic & Medicinal Chemistry251471-148020173.0
    •  
    Banerjee, A.G., Das, N., Shengule, S.A., Sharma, P.A., Srivastava, R.S. & Shrivastava, S.K.Design, synthesis, evaluation and molecular modelling studies of some novel 5, 6-diphenyl-1, 2, 4-triazin-3 (2H)-ones bearing five-member heterocyclic moieties as potential COX-2 inhibitors: A hybrid pharmacophore approach.Bioorganic Chemistry69102-12020164.8
    •  
    Shrivastava, S.K., Batham, A., Sinha, S.K., Parida, T.K., Garabadu, D. & Choubey, P.K.Design, synthesis and evaluation of novel thiazolidinedione derivatives as anti-hyperglycemic and anti-hyperlipidemic agents.Medicinal Chemistry Research252258-226620161.27
    •  
    Banerjee, A.G., Kothapalli, L.P., Sharma, P.A., Thomas, A.B., Nanda, R.K., Shrivastava, S.K. & Khatanglekar, V.V.A facile microwave assisted one pot synthesis of novel xanthene derivatives as potential anti-inflammatory and analgesic agents.Arabian Journal of Chemistry9S480-S48920164.76
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    Shah, K., Chabbraa, S., Agrawala, N., Upadhyaya, P.K., Shrivastavab, S.K., Upmanyuc, N. & Mishraa, P.Synthesis and biological evaluation of substituted benzimidazoles.J. Indian Chemical Society931009-101820160.11
    •  
    Pandit, N., Shah, K., Agrawal, N., Upmanyu, N., Shrivastava, S.K. & Mishra, P.Synthesis, characterization and biological evaluation of some novel fluoroquinolones.Medicinal Chemistry Research
     
    25843-85120161.27
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    Banerjee, A.G., Das, N., Shengule, S.A., Srivastava, R.S. & Shrivastava, S.K.Synthesis, characterization, evaluation and molecular dynamics studies of 5, 6–diphenyl–1, 2, 4–triazin–3 (2H)–one derivatives bearing 5–substituted 1, 3, 4–oxadiazole as potential anti–inflammatory and analgesic agents.European Journal of Medicinal Chemistry10181-9520155.57
    •  
    Shah, K., Shrivastava, S.K. & Mishra, P.Formulation and evaluation of suspensions: Mefenamic acid prodrugs.Pakistan Journal Pharmaceutical Sciences27-20140.64
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    Shah, K., Shrivastava, S.K. & Mishra, P.Synthesis, Kinetics and Pharmacological Comparison of a Mutual Prodrug of Mefenamic Acid to Related Physical Mixture.Pharmaceutical Chemistry Journal48253-25920140.44
    •  
    Das, N., G Banerjee, A. & K Shrivastava, S. DesignSynthesis and Pharmacological Evaluation of N3 Aryl/Heteroaryl Substituted 2-((Benzyloxy and Phenylthio) Methyl) 6, 7-dimethoxyquinazolin-4 (3H)-ones as anticonvulsants.Medicinal Chemistry10800-80920142.33
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    Das, N., Garabadu, D., Banerjee, A.G., Krishnamurthy, S. & Shrivastava, S.K.Synthesis and pharmacological evaluation of some N3-aryl/heteroaryl-substituted 2-(2-chlorostyryl)-6, 7-dimethoxy-quinazolin-4 (3H)-ones as potential anticonvulsant agents.Medicinal Chemistry Research234167-417620141.27
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    Sreelakshmi, V., Uma Maheshwari Rao, V., Pugazhendhy, S., Shrivastava, S. & Sunitha, M.Development and validation of simvastatin by RP-HPLC method in bulk drug and pharmaceutical dosage forms.American Journal of Pharmaceutical Technology & Research3 (5)-20130.98
    •  
    Sinha, S.K. & Shrivastava, S.K.Design, synthesis and evaluation of some new 4-aminopyridine derivatives in learning and memory.Bioorganic & Medicinal Chemistry Letters
     
    232984-298920132.45
    •  
    Shukla, S., Srivastava, R.S., Shrivastava, S.K., Sodhi, A. & Kumar, P..Synthesis, cytotoxic evaluation, docking and in silico predictions of 4-arylideneamino/cycloalkylidineamino 1, 2-naphthoquinone thiosemicarbazonesJournal of Enzyme Inhibition and Medicinal Chemistry281192-119820134.29
    •  
    Shah, K., Chhabra, S., Shrivastava, S.K. & Mishra, P.Benzimidazole: a promising pharmacophore.Medicinal Chemistry Research225077-510420131.27
    •  
    Sinha, S.K. & Shrivastava, S.K.Synthesis, evaluation and molecular dynamics study of some new 4-aminopyridine semicarbazones as an antiamnesic and cognition enhancing agents.Bioorganic & Medicinal Chemistry21
     
    5451-546020133.0
    •  
    Sreelakshmi, V., Rao, V.U.M., Pugazhendhy, S. & Shrivastava, S.K.Study of forced degradation behavior of simvastatin by rp–hplc and development of a validated stability indicating assay method.Inventi Rapid: Pharm Analysis & Quality Assurance--2013-
    •  
    Shrivastava, P., Shrivastava, A., Sinha, S. & Shrivastava, S.K.Dextran carrier macromolecules for colon-specific delivery of 5-aminosalicylic acidIndian Journal of Pharmaceutical Sciences7527720130.66
    •  
    Shukla, S., Srivastava, R., Shrivastava, S., Sodhi, A. & Kumar, P.Synthesis, characterization, in vitro anticancer activity, and docking of Schiff bases of 4-amino-1, 2-naphthoquinone.Medicinal Chemistry Research221604-161720131.27
    •  
    Shah, K., Shrivastava, S.K. & Mishra, P.Evaluation of mefenamic acid mutual prodrugs.Medicinal Chemistry Research2270-7720131.27
    •  
    Das, N., Dash, B., Dhanawat, M. & Shrivastava, S.Design, synthesis, preliminary pharmacological evaluation, and docking studies of pyrazoline derivatives.Chemical Papers
     
    6667-7420121.25
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    Sinha, S.K., Praveen, B., Shrivastava, P.K. & Shrivastava, S.K.Synthesis, characterization and biological evaluation of some glutathione inducing amino acid conjugates of valproic acid with reduced hepatotoxicity.Asian Pacific Journal of Tropical Disease2
     
    S218-S22220121.13
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    Shah, K., Shrivastava, S.K. & Mishra, P.Synthesis, kinetics and pharmacological evaluation of mefenamic acid mutual prodrug.Acta Poloniae Pharmaceutica70905-97720120.74
    •  
    Sinha, S.K. & Shrivastava, S.K.Synthesis and evaluation of some new 4-aminopyridine derivatives as a potent antiamnesic and cognition enhancing drugs.Medicinal Chemistry Research214395-440220121.27
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    Dhanawat, M., Banerjee, A.G. & Shrivastava, S. K.Design, synthesis, and anticonvulsant screening of some substituted piperazine and aniline derivatives of 5-phenyl-oxazolidin-2, 4-diones and 5, 5-diphenylimidazolidin-2, 4 diones.Medicinal Chemistry Research212807-282220121.27
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    Kulshrestha, A., Dhanawat, M., Das, N. & K Shrivastava, S.Small Molecules Antileishmanials: A Review.Letters in Drug Design & Discovery9535-54820121.17
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    Shukla, S., Kumar, P., Das, N., Hari Narayana Moorthy, N., Shrivastava, S., Trivedi, P. & Shyam Srivastava, R.Synthesis, characterization, biological evaluation and docking of coumarin coupled thiazolidinedione derivatives and its bioisosteres as PPARγ agonists.Medicinal Chemistry8834-84520122.33
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    Das, N., Dhanawat, M. & Shrivastava, S.K.An overview on antiepileptic drugs.Drug Discoveries & Therapeutics6178-19320121.47
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    Shukla, S., Srivastava, R., Shrivastava, S., Sodhi, A. & Kumar, P.Synthesis, characterization and antiproliferative activity of 1, 2-naphthoquinone and its derivatives.Applied Biochemistry and Biotechnology1671430-144520121.75
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    Namdeo, K.P., Shrivastava, S.K. & Chandra, R.Synthesis and In-vivo Anti-convulsant Activity of Prodrug of 3-Alkylglutamic Acid in Albino Rats.Indian Journal of Pharmaceutical Educationand Research46179-18420120.25
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    Shukla, S., Srivastava, R.S., Shrivastava, S.K., Sodhi, A. & Kumar, P.Synthesis, molecular docking and biological evaluation of 4-cycloalkylidineamino 1,2-naphthoquinone semicarbazones as anticancer agents.Asian Pacific Journal of Tropical Biomedicine2
     
    S1040-S104620121.70
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    Sinha, S.K., Shrivastava, P.K. & Shrivastava, S.K.Development and validation of a HPLC method for the simultaneous estimation of amlodipin and telmisartan in pharmaceutical dosage form.Asian Pacific Journal of Tropical Biomedicine2
     
    S312-S31520121.70
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    Shukla, S., Kumar , P., Moorthy, N., Shrivastava, S., Trivedi, P. & Srivastava, R.QSAR Studies on trans-3, 4’-bispyridinylethylenes as a potent and novel inhibitor of Protein Kinase b (PKB) having inhibitory action against myeloma cells.International Journal of Pure and Applied Chemistry679-872011-
    •  
    Dhanawat, M., Das, N. & Shrivastava, S.K.Design, synthesis, anticonvulsant screening and 5HT1A/2A receptor affinity of N (3)-substituted 2, 4-imidazolidinediones and oxazolidinediones.Drug Discoveries &Therapeutics
     
    5227-23720111.47
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    Sinha, S.K., Shrivastava, P.K. & Shrivastava, S.K.Synthesis, characterisation, and biological activity of three new amide prodrugs of lamotrigine with reduced hepatotoxicity.Chemical Papers6570-7620111.25
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    Namdeo, K. & Shrivastava, S.K.Synthesis and Anticonvulsant Activity of Prodrug of Gabapentin.Asian Journal of Chemistry23186120110.14
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    Pugazhendhy, S., Shrivastava, P.K., Sinha, S.K. & Shrivastava, S.K.Lamotrigine–dextran conjugates-synthesis, characterization, and biological evaluation.Medicinal Chemistry Research20
     
    595-60020111.27
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    Das, N., Dhanawat, M., Kulshrestha, A. & K Shrivastava, S. K.Pharmacophoric modeling and atom-based 3D-QSAR of novel 1-Aryl-3-(1-acylpiperidin-4-yl) urea as human soluble epoxide hydrolase inhibitors (sEHIs).Medicinal Chemistry7581-59220112.33
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    Shrivastava, P.K., Singh, R. & Shrivastava, S.K.Dextran successful carrier molecule for the delivery of NSAIDs with reduced gastrointestinal effect.Journal of Drug Delivery Science and Technology2013520101.19
    •  
    Das, N., Dhanawat, M., Dash, B., Nagarwal, R. & Shrivastava, S.Codrug: an efficient approach for drug optimization.European Journal of Pharmaceutical Sciences41571-58820103.75
    •  
    Shrivastava, P., Singh, R. & Shrivastava, S. K.Polyamidoamine dendrimer and dextran conjugates: preparation, characterization, and in vitro and in vivo evaluation.Chemical Papers64592-60120101.25
    •  
    Verma, A., Das, N., Dhanawat, M. & Shrivastava, S.K.Conjugation of some NSAIDs with 5-phenyl-2-aminothiazole for reduced ulcerogenicity.Thai J Pharm Sci3449-5720100.13
    •  
    Shukla, S., Kumar, P., Srivastava, R. & Trivedi, P.RP-HPLC method development and its validation for simultaneous estimation of Alprazolam and Fluoxetine hydrochloride in pharmaceutical dosage form.Eurasian Journal of Analytical Chemistry5239-2452010-
    •  
    Namdeo, K., Shekhar, V., Bodakhe, S., Shrivastava, S.K. & Dangi, J.Chemical investigations of honey: a multiactive component of herbal therapeutic agent.International Journal of Research in Ayurveda and Pharmacy (IJRAP)185-8920100.36
    •  
    Shrivastava, P. &  Shrivastava, S. K.Dextran carrier macromolecule for colon specific delivery of celecoxib.Current drug Delivery7144-15120102.51
    •  
    Dhanawat, M. & Shrivastava, S.K.Solid-phase synthesis of oligosaccharide drugs: a review.Mini Reviews in Medicinal Chemistry9169-18520092.66
    •  
    Dhanawat, M., Das, N., Nagarwal, R.C. & Shrivastava, S. K.Antimalarial drug development: past to present scenario.Mini Reviews in Medicinal Chemistry9
     
    1447-146920092.66
    •  
    Shrivastava, P.K., Basniwal, P.K., Shrivastava, S.K. & Jain, D.Validated RP-HPLC method for estimation of ezetimibe in different tablet dosage form.Int. J. Ph. Sci1174-1812009-
    •  
    Shrivastava, P.K. & Shrivastava, S.K.Stress stability studies and the estimation of lamotrigine in pharmaceutical formulation by validated RP-HPLC method.Indian Journal of Pharm. Education & Research43156-16120090.25
    •  
    Shrivastava, P. & Shrivastava, S.Dextran polysaccharides: successful macromolecular carrier for drug delivery.Int J Pharm Sci1353-3682009-
    •  
    Praveen, B., Shrivastava, P. & Shrivastava, S.K.In-Vitro release and pharmacological study of synthesized valproic acid-dextran conjugate.Acta Pharmaceutica Sciencia51169-17620090.14
    •  
    Shrivastava, P., Basniwal, P., Jain, D. & Shrivastava, S.Concurrent estimation of clopidogrel bisulfate and aspirin in tablets by validated RP-HPLC method.Indian Journal of Pharmaceutical Sciences7066720080.66
    •  
    Das, N., Verma, A., Shrivastava, P.K. & Shrivastava, S.K.Synthesis and biological evaluation of some new aryl pyrazol-3-one derivatives as potential hypoglycemic agents.Indian Journal of Chemistry-B47B1555-155820080.35
    •  
    Shrivastava, S.K., Jain, D., Shrivastava, P.K. & Trivedi, P.Flurbiprofen and Suprofen Conjugates: Synthesis, Characterization and Biological Evaluation.Tropical Journal of Pharmaceutical Research8221-22920080.56
    •  
    Shrivastava, S.K., Shrivastava, P.K. & Praveen, B.Synthesis, Characterization, and Biological Evaluation of Some New Derivatives of Valproic acid and Gabapentin: A Prodrug Approach.Journal of Pharmacy and PharmacologyIA-1920082.40
    •  
    Shrivastava, P.K., Basniwal, P.K. & Jain, D.Alkaline Hydrolysis of Pioglitazone Hydrochloride by RP-LC: Stress Stability Study.Acta Pharmaceutica Sciencia5041-4620080.14
    •  
    Shrivastava, P., Basniwal, P., Saxena, V., Jain, D. & Shrivatava, S.K.Simultaneous estimation of atorvastatin calcium and aspirin in capsule dosage form by validated RP-HPLC method.Journal of Pharmaceutical Research6126-12820071.35
    •  
    Namdeo, K., Shrivastava, S. & Chandra, R.Synthesis and antiparkinson activity of mutual prodrug and chemical delivery systemJournal of the Institution Chemist (India)7997-1102007-
    •  
    Namdeo, K.P., Bodakhe, S., &Shrivastava, S.Phytochemical and biological investigation on calotropis procera.Journal of Science and Pharmacy8137-1402007-
    •  
    Karthikeyan, C., Kumar, P.M., Moorthy, N., Shrivastava, S. & Trivedi, P.Quantitative structure activity relationships of some selective inhibitors of glucagon receptor: A hansch approach.Asian J. Biochem1307-31520061.17
    •  
    Jaiswal, D., Karthikeyan, C., Shrivastava, S.K. & Trivedi, P.QSAR modeling of sulfonamide inhibitors of histone deacetylase.Internet Electron. J. Mol. Des5345-35420060.5
    •  
    Shrivastava, P., Basniwal, P.K., Jain, D. & Shrivastava, S.K.RP- HPLC Method for estimation of pioglitazone hydrochloride in tablet formulationAsian Journal of Pharmaceutics155-5920060.46
    •  
    Shrivastava, S., Jain, D. & Trivedi, P.Dextrans—potential polymeric drug carriers for suprofen.Die Pharmazie58
     
    804-80620031.13
    •  
    Shrivastava, S., Jain, D. & Trivedi, P.Dextrans–potential polymeric drug carriers for flurbiprofen.Die Pharmazie58389-39120031.13
    •  
    Shrivastava, S.K., Singh, G. & Basniwal, P.K.Boswillic acid: an alternative anti-inflammatory therapy.Indian Journal of Natural Products1914-202003-
    •  
    Mathur, P., Parashar, K., Shrivastava S. & Shrivastava, S.K.Synthesis of a novel metal chelating ion exchange resin specific for zincIndian Journal of Chemistry- Section A39A1327-133020000.49
    •  
    Shrivastava, S.K., & Bhandari, A.Review Article: Managment of Schizophrenia.Indian Drugs34617-62419970.14
    •  
    Shrivastava, S., Uppadhyay, R., Trivedi, P. & Jain, D.Synthesis and Evaluation of Amino Acid Analogues of Valproic Acid.Indian Drugs33571-57319960.14

 

 

S. No.Patent TitleName of ApplicantPatent No.Award DateAgency/ CountryStatus
1.A Process for Preparation of Pharmaceutical Active Novel N-(9-(4- chlorophenyl)-3- hydroxy-9H- xanthene-7-yl)- acetamide.Modgalya, D., Banerjee, A.G., Sharma, P., Shrivastava, S.K., Bhattacharjee, J. and Singh, S.3858/DEL/2011Published- 02.06.2017IndiaPublished
2.Choline Esterase Inhibiting Compounds, Compositions and Process ThereofShrivastava, S.K., & Sinha, S.201611011127Published- 26.01.2018IndiaPublished
3.Compositions and methods for reducing cell viabilityShrivastava. S.K., Srivsatava, R.K., Shankar, S., Tripathi, P.N., Srivastava, P.2932719-019-US1Filed- 30.04.2018United StatesFiled
4.Methods for treating cancer and metabolic syndromeShrivastava. S.K., Srivsatava, R.K., Shankar, S.,Tripathi, P.N., Srivastava, P., Sharma P.2932719-025-US1Filed- 04.05.2018United StatesFiled
5.5-Oxoisoxazolidine– 2–carboxamide compounds as inhibitors of cyclo- oxygenase and lipo- oxygenase as anti- inflammatory analgesic agentsShrivastava, S.K., Yadav, S., Tripathi, P.N. & Srivastava, P.201811019910Filed- 28.05.2018IndiaFiled
6.Composition and methods for treating cancerShrivastava, S.K., Shrivastava, R., Shrivastava, S, Tripathi, P.N. & Srivastava, P.62/728439-2932719-053-US1Filed- 07.09.2018United StatesFiled
7.Synthesis of N-benzylpiperidine and 5-(2,4-dichlorophenyl)-1,3,4-oxadiazole hybrid with multifunctional activities against Alzheimer’s DiseaseSharma, P., Tripathi, A., Tripathi P.N., Avhad, A., Shrivastava, S.K.201911034164Filed- 24.08.2019IndiaFiled
8.A novel compound for treating Alzheimer's disease and a method of preparation thereofTripathi, A., Sharma, P., Choubey, P.K., Shrivastava, S.K.201911034300Filed- 26.08.2019IndiaFiled
9.N-(1-benzylpiperidin-4-yl)-5-(4-(trifluoromethyl)
phenyl)-1,3,4-oxadiazol-2-amine as multitargeted
ligand to treat Alzheimer’s disease
Sharma, P., Tripathi, A., Tripathi P.N., Salunke, P., Shrivastava, S.K.201911034930Filed- 29.08.2019IndiaFiled
10.Synthesis of 2-(4-bromophenyl)-5-(4-(pyridin-2-yl)Piperazin-1-yl)-1,3,4-oxadiazole for treating Alzheimer's disease and method of preparation thereofTripathi, A., Sharma, P., Choubey, P.K., Shrivastava, S.K.201911034931Filed- 29.08.2019IndiaFiled
11.Composition and Methods for treating cancerPrabhash Nath Tripathi and Pavan Srivastava Rakesh srivastava,Sharmila Shankar, Sushant Kumar ShrivastavaUS 11,286,241 B2Published- 29.03.2022United StatesPublished
12.Compositions and methods for treating cancerRakesh K Srivastava, Sharmila Shankar, Sushant Kumar Shrivastava, Prabhash Nath Tripathi, Pavan Srivastava11286241Published- 29.03.2022United StatesPublished
13.A method for synthesis of a symmetrical urea derivative for the management of Alzheimer’s diseaseKumar Hansal, Shrivastava, S.K.202411059649Filed-07.08.2024IndiaPublished
14. A heterocyclic compound and a method of synthesis thereofKumar Hansal, Shrivastava, S.K.202511034998Filed-09.04.2025IndiaFiled
15.A cholinesterase inhibiting compound for neurodegenerative conditions and a method of synthesis thereofKumar Hansal, Shrivastava, S.K. 202511034997Filed-09.04.2025IndiaFiled
  • Tripathi MK, Shrivastava SK, Karthikeyan S, Sinha D, Nath A. Application of Machine Learning and Molecular Modeling in Drug Discovery and Cheminformatics. InAdvanced AI Techniques and Applications in Bioinformatics 2021 Oct 17 (pp. 201-214). CRC Press.
  • Sharma P, Tripathi MK, Shrivastava SK. Cholinesterase as a Target for Drug Development in Alzheimer’s Disease. In: Labrou N. (eds) Targeting Enzymes for Pharmaceutical Development. Methods in Molecular Biology, vol 2089. Humana, New York, NY 2020.
  • Tripathi MK, Sinha J, Srivastava SK, Kumar D. Bioinformatics in Skin Cancer: A System Biology Approach to Understanding the Molecular Mechanisms and It’s Regulations. In: Dwivedi A., Agarwal N., Ray L., Tripathi A. (eds) Skin Aging & Cancer. Springer, Singapore 2019.
  • Kumar M, Sharma P, Maheshwari R, Tekade M, Shrivastava SK, Tekade RK. Beyond the Blood–Brain Barrier: Facing New Challenges and Prospects of Nanotechnology-Mediated Targeted Delivery to the Brain, Elsevier (Academic Press), 2018, pp. 397-437.
  • Das N, Sharma PA, Seth A, Maheshwari R, Shrivastava SK, Tekade RK, Chapter 5- An overview of dendrimers and its biomedical applications, Apple Academic Press, A CRC Press (Taylor & Francis) 2018.
  • Seth A, Sharma PA, Maheshwari R, Shrivastava SK, Tekade RK. Chapter 7- Dendrimers in targeted drug delivery, Apple Academic Press, A CRC Press (Taylor & Francis) 2018.
  • Sharma PA, Maheshwari R, Shrivastava SK, Tekade RK. Chapter 9- Dendrimers in gene delivery, Apple Academic Press, A CRC Press (Taylor & Francis), 2018.
  • Dhanawat M, Sharma GK, Shrivastava SK. The new heteroaryl compounds having 5-HT1A/5-HT2A affinity- Design, synthesis & evaluation of some new heteroaryl compounds having 5-HT1A/5-HT2A affinity and anticonvulsant activity, Lap Lambert Academic Publishing,2015, ISBN: 978-3-659-69488-2.

Former Post-Doctoral Fellow (PDF)  

(1) Dr. Manish Kumar 
(2) Dr. Chhand Charan Danta 

Ph.D Supervised-  19
(1) Mr. K.P. Namdeo (Awarded-2005, Bundelkhand University, Jhansi)
(2) Ms. Mousumi Besan (Awarded-2020)
(3) Mr. Avanish Tripathi (Awarded-2022)
(4) Mr. Piyoosh Sharma (Awarded-2023)
(5) Mr. Prabhash Nath Tripathi (Awarded-2019)
(6) Mr. Pavan Srivastava (Awarded-2020)
(7) Mr. Ankit Seth (Awarded-2019)
(8) Mr. Anupam G. Banerjee (Awarded-2017)
(9) Mr. Kamal Shah (Awarded-2016, A. P. J Abdul Kalam Technical University, Lucknow)
(10) Mr. Nirupam Das (Awarded-2015)
(11) Mr. Saurabh Kumar Sinha (Awarded-2014)
(12) Ms. Shubhanjali Shukla (Awarded-2014)
(13) Ms. Meenakshi Dhanawat (Awarded-2013)
(14) Mr. Prabhat Kumar Shrivastava (Awarded-2010)
(15) Ms. Priyanka Kumari Choubey (Awarded-2022)
(16) Mr. Rajeev Kumar (Awarded, A. P. J Abdul Kalam Technical University, Lucknow) 
(17) Mr. Digambar Kumar Waiker (Awarded-2023)
(18) Mr. Akash Verma (Awarded-2024)
(19) Ms. Poorvi Saraf (Awarded-2025)
 

Ph.D. Supervision ongoing-                                              07 
(1) Ms. Bhagwati Bharadwaj (Thesis Submitted)
(2) Mr. Anoop Kumar Tiwari
(3) Mr. Hansal Paresh Kumar
(4) Mr. Abhinav Singh
(5) Ms. Samridhi Shrivastava
(6) Mr. Sachin Kumar Vishwakarma
(7) Ms. Shreya Nandu Londhe
 

M.Pharm Thesis Dissertation Supervised-                         35       
(1) Mr. Mahfooz Khan (Awarded-2025)
(2) Mr. Neelesh Kumar Yadav (Awarded-2025)
(3) Mr. Kshirodh (Awarded-2024)
(4) Ms. Deekhsa Nigam (Awarded-2024)
(5) Mr. Pidagu Kiran (Awarded-2022)
(6) Ms. Srashti Namdeo (Awarded-2021)
(7) Ms. Nidhi Namdeo (Awarded-2021)
(8) Ms. Nishi Jain (Awarded-2021)
(9) Mr. Prashant Salunke (Awarded-2020)
(10) Mr. Ashok Avhad (Awarded-2020)
(11) Mr. Sombir (Awarded-2018)
(12) Ms. Poorvi Saraf (Awarded-2018)
(13) Ms. Puja Mishra (Awarded-2017)
(14) Mr. Munish Kumar (Awarded-2016)
(15) Ms. Sujata Yadav (Awarded-2016)
(16) Mr. Ambreesh Kumar Verma (Awarded-2016)
(17) Mr. Ashish Tripathi (Awarded-2016)
(18) Ms. Priyanka Kumari Choubey (Awarded-2015)
(19) Ms. Ojaswi Sinha (Awarded-2015)
(20) Mr. TVR Upendra (Awarded-2015)
 


M.Pharm Thesis Dissertation supervision ongoing-           02

  • Selected as an External Member for the review and examination for the manufacturing of medicine under Sowa Rigpa Pharmacopoeia
  • Professor-In-Charge, Outreach and Industry Relations, IIT(BHU) Varanasi
  • Professor-In-Charge, Center for Faculty Development and Educational Technology (CFDET), IIT(BHU) Varanasi
  • Coordinator Training & Placement Cell, IIT(BHU), Varanasi.
  • Former Head of Department, Pharmaceutical Engineering & Technology, IIT(BHU) Varanasi
  • BoG Nominee from UGC at Seven Hills College of Pharmacy, Tirupati, Andhra Pradesh, India.
  • Life Time Achievement Award in Pharmacy (19-12-2024) Association of Biotechnology and Pharmacy, Award for Distinguished and Dedicated service to the Profession in the Field of Biotechnology and Pharmacy. 

  • Illustrious Aluminous Award from “Dr. H.S. Gour Vishwavidyalaya, Department of Pharmaceutical Sciences, Sagar (M.P.)” 2016
  • Best Poster Award for the presentation entitled “Synthesis, evaluation and docking studies of some novel 1,2,4-triazine derivatives bearing five member heterocyclic moiety as potential anti-inflammatory and analgesic agents” in “Pharma Middle East - 2015” held from 02nd - 04th, November 2015 at Dubai, UAE.
  • Certified for Leadership for Academicians Programme organised by Michigan Ross Executive Education and IIT ROPAR from Nov 17- Dec 07, 2018
  • Prof. S. B. Sonawane memorial award for the Best Paper in IJPER publication, 2012
  • Senior scientist award from “European Institute of Scientific Research on Ayurveda (EISRA)” 2015 Netherland
  • Best paper award - St. John’s Pharmacy College award for the Best Paper in Pharmaceutical Analysis. IJPR, 2009
  • St. John’s Pharmacy College Award for Best Paper in Pharmaceutical Analysis for the article entitled “Stress Stability Studies and the Estimation of Lamotrigine in Pharmaceutical Formulation by Validated RP-HPLC Method” organized by Indian Journal of Pharmaceutical Education and Research, APTI- 15Annual National Convention Hyderabad. (2-3 November 2010).
  • St. John’s Pharmacy College award for the Best Paper in Pharmaceutical Analysis. “Stress Stability Studies and Estimation of Lamotrigine in Pharmaceutical Formulation by validated RP-HPLC method” IJPR, 43, 2009,156-161.
  1. Mr. Digambar Kumar Waiker has been selected as SERB-Overseas Visiting Doctoral Fellow at Purdue University under the supervision of Dr. Vincent Jo Davisson. (Jan 2019 - May 2020) 
  2. Ms. Bhagwati Bhardwaj has been selected as SERB-Overseas Visiting Doctoral Fellow at Purdue University under the supervision of Dr. Vincent Jo Davisson. (Jan 2022 - Jan 2023) 
  3. Mr. Hansal Paresh Kumar has been awarded India’s Prestigious – Prime Minister’s Research Fellowship (PMRF) in the May Cycle-09, 2022.
  4. Mr. Abhinav Singh has been selected as ANRF-Overseas Visiting Doctoral Fellow at Purdue University under the supervision of Dr. Vincent Jo Davisson. (Aug 2024 - Jan 2026)