Dr. Ruchi Chawla

Associate Professor
Department/School/Unit Name
Department of Pharmaceutical Engineering and Technology IIT BHU
Phone No(s): 9336077707
Email: rchawla.phe@iitbhu.ac.in
Area of Interest: Pharmaceutics

Courses Taught: 
1. Undergraduate: 

  • Introduction Pharmaceutical Sciences and Technology
  • Physical Pharmaceutics
  • Pharmaceutical Technology
  • Stream Project (Hons.)
  • Pharmaceutical Management
  • Quality Assurance
  • Industrial Pharmacy
  • Dosage Formulation Design
  • Seminar

​​2. Post-graduate:

  • Advanced Biopharmaceutics
  • Industrial Pharmacy
  • Pharmacokinetics
  • PG Seminar

3. Ph.D.

  • Research Methodology
  • Advanced Biopharmaceutics

S. No.

Funding Agency, Role and Duration

Project Title

Grant amount

Stauts

1

ICMR

PI, 2024-2027

Development and evaluation of Intra-nasal nanocarriers for the treatment of Alzheimer’s disease

Rs. 60.96 lakhs

Ongoing

2

ASPIRE, CSIR

Co-PI, 2024-2027

Designing norfloxacin CuNPs and EGF-Loaded multi-layered wound dressing for burn wound

Rs. 30.0 lakhs

Ongoing

3

 Institute Research Project, IIT(BHU)

PI

Nanocarriers for brain delivery

Rs 15 Lakhs

Completed

4

Sprouting Grant, IIT(BHU),

Co-PI

Exploring the Nanotechnological based approaches for drug products

Rs 25 Lakhs

Completed

Sl.

No.

Author (s)

Title

Name of Journal

Volume

Page No.

Year

Mohini Mishra , Rinki Verma , Aditya Sharma, Krishan Kumar , Ruchi Chawla

Evaluation of Gemcitabine and Epigallocatechin-3-Gallate Loaded Solid Lipid Nanoparticles on Benzopyrene Induced Lung Cancer Model Via Intranasal Route: Improved Pharmacokinetics and Safety Profile

AAPS PharmSciTech. 2024d

doi: 10.1208/s12249-024-02892-w.

25(6)

176

2024

Mohini Mishra, Kirti Wasnik, Aditya Sharma, Krishan Kumar, Rinki Verma, Pradip Paik, Ruchi Chawla

Epigallocatechin-3-gallate Synergistically Inhibits the Proliferation of Lung Cancer Cells with Gemcitabine by Induction of Apoptosis Mediated by ROS Generation

ACS Applied Bio Materials

DOI: 10.1021/acsabm.4c00958

2024

Akhilesh Kumar Yadav, Himanshu Tripathi, Sanjna Rajput, Priya Singh, Ashutosh Kumar Dubey, Krishan Kumar, Ruchi Chawla, Chandana Rath

Drug kinetics and antimicrobial properties of quaternary bioactive glasses 81S (81SiO2-(16-x) CaO-2P2O5-1Na2O-xMgO); an in-vitro study

Biomaterials Advances

157

213729

2024

Krishan Kumar, Rinki Verma, Manjit, Priya, Mohini Mishra, Varsha Rani, Ruchi Chawla

In Vivo Cancer Microenvironment Responsive Glycan Receptor-Targeted Nanoparticles for Gemcitabine Delivery to Benzo[a]pyrene-Induced Lung Cancer Model

AAPS PharmSciTech

25

2

2023

Krishan Kumar, Shiv Govind Rawat, Mohini Mishra, Ajay Kumar, Ruchi Chawla

Dual targeting pH responsive chitosan nanoparticles for enhanced active cellular internalization of gemcitabine in non-small cell lung cancer

International Journal of Biological Macromolecules

249

126057

2023

Rani, V., Verma, R., Kumar, K. and Chawla, R.

pH influenced Self-assembled Stealth Nanoscaffolds encapsulating Memantine for the treatment of Alzheimer’s disease

Journal of Biosciences

(I.F. 2.795)

48

-

2023

Varsha Rani, Rinki Verma, Krishan Kumar, Ruchi Chawla

Role of pro-inflammatory cytokines in Alzheimer's disease and neuroprotective effects of pegylated self-assembled nanoscaffolds

Current Research in Pharmacology and Drug Discovery (I.F. 5.547)

4

100149

2023

Varsha Rani, Ruchi Chawla

Design, fabrication, optimization and characterization of memantine-loaded biodegradable PLGA nanoscaffolds for treatment of Alzheimer’s disease

Biomedical Materials

(I.F. 3.715)

17

065024

2022

Payal Singh, Ruchi Chawla, Ajai Kumar Pandey, JK Mishra, Rashmi Singh

Comparative evaluation of two intranasal forms of Curcumin: Quantitation and impact on mice model of asthma

Phytomedicine Plus

3

100413

2023

K Kumar, V Rani, M Mishra, R Chawla

New paradigm in combination therapy of siRNA with chemotherapeutic drugs for effective cancer therapy

https://doi.org/10.1016/j.crphar.2022.100103.

Current Research in Pharmacology and Drug Discovery

(IF 5.547)

3

100103

2022

R Chawla, V Karri, V Rani, M Mishra, K Kumar

Factorial Design-Based Nanocarrier Mediated Formulation of Efavirenz and Its Characterization

https://doi.org/10.1142/S1793984422500027

Nano LIFE

12

2250002

2022

Ruchi Chawla

Bhupendra Sahu, Mohini Mishra, Varsha

Rani, Rashmi Singh

Intranasal Micellar Curcumin for the treatment of Chronic Asthma

https://doi.org/10.1016/j.jddst.2021.102922

Journal of drug delivery science And technology,

67

102922

2022

KrishanKumar,

Ruchi Chawla

Nanocarriers-mediated

therapeutics   as   a   promising approach   for   treatment   and

diagnosis of lung cancer

https://doi.org/10.1016/j.jddst.2021.102677

Journal of drug delivery science

and technology,

IF:3.981

65

102677

2021

Ruchi Chawla, Varsha Rani, Mohini Mishra

Changing paradigms in the treatment of Tuberculosis

https://doi.org/10.1016/j.ijtb.2021.08.034

Indian Journal of Tuberculosis

69

389-403

2021

Chawla R, Patel R,

Mishra M

Development and Validation of Ion  Exchange  Chromatographic Method for the Quality Control

of Extract of Hordeum Vulgare

Acta   Scientific   Pharmaceutical

Sciences, IF:

0.789

5(1)

9-16 

2020

Varsha Rani, Ruchi

Chawla, Neelam

Verma

Formulation and Evaluation of Negatively Charged Liposomes of Sertraline Hydrochloride for Antidepressant Activity

https://doi.org/10.22377/ajp.v14i2.3616

Asian  Journal  of  Pharmaceutics, IF: 0.47

14(2)

211-19

2020

Chauhan T, , Sahu B,

Sharma S, Kheruka

SC, Gambhir S, Dubey V, Aggarwal

LM, Chawla R

Negatively Charged Liposomes

of Sertraline Hydrochloride:

Formulation, Characterization

and Pharmacokinetic Studies

https://doi.org/10.1016/j.jddst.2020.101780

Journal of drug delivery science

and technology, IF:3.981

58

101780

2020

Deb A, Mandurnekar

AA, Rani V,

Chauhan T, Mishra

B, Chawla R.

Formulation and evaluation of curcumin loaded nanofilms for the treatment of wounds.

SPER J Pharm Biol Res

1(1)

5-9

2018

Jha RK, Yadav SK,

Chawla R, Pandey S,

Mishra B.

Development and evaluation of microsphere based

mucoadhesive discs of

raloxifene hydrochloride

SPER J Pharm Biol Res

2018;1(1):14-19

1(1)

14-19

2018

Chawla R, Chauhan

A.

Transdermal Delivery of Nigella sativa Oil for Topical

Application in 1-Chloro-2, 4- Dinitrobenzene- Induced Atopic Dermatitis in Rats

Journal of PharmaSciTech

6(20)

1-9

2016

Subhashini S,

Chauhan PS, Chawla

R, Singh R,   Dash D

Pharmacokinetic of nasal

curcumin: An approach for

asthma medication.

Chinese journal of pharmacology

and toxicology,

IF: 0.08

29 (S1)

57-

58

2015

Mishra B,

Chaturvedi N,

Chawla R

Silymarin: Recent Approaches for Enhancing Bioavailability

PhTechMed,

IF: 0.654

3 (3)

455-460

2014

Chawla R, Singh

RK, Mishra B.

RP-HPLC Method for

Simultaneous Estimation of

Anti-Tubercular Drugs in Fixed

Dose Combination Tablets

Journal of Advanced Research in

Applied Chemistry & Chemical

Engineering

1 (1)

10-25

2014

Chawla R, Solanki HS, Gambhir S,

Kheruka SC, Dube V, Aggarwal LM,

Mishra B

Formulation, Characterization

and biodistribution studies of

poly lactide-co-glycolide

nanoparticles of Anti-Tubercular drugs

https://doi.org/10.4155/tde.14.88

Therapeutic Delivery, IF: 2.4

5 (12)

1247-1259

2014

Subhashini S,

Chauhan  PS,

Kumari S, Kumar JP,

Chawla R, Dash D,

Singh M, Singh R.

Intranasal curcumin and its

evaluation in murine model of asthma

https://doi.org/10.1016/j.intimp.2013.08.008

International

Immunopharmacology,

IF:2.75

17(3)

733-743

2013

Chawla R., Jaiswal

S., Mishra B

Development and optimization

of polymeric nanoparticles of Anti-tubercular drugs using central composite factorial design

https://doi.org/10.1517/17425247.2013.807794

Expert opinion on drug delivery,

IF: 4.896

11 (1)

31-43

2013

    1. A Nano-formulation for Management of Lung Cancer and A Method of Preparation thereof. Indian Patent application No.: 202311081092, submitted November 2023.
    2. A nanoparticle-based composition and a method of preparation thereof. Indian Patent Application No.: 202311074704, submitted November 2023.
    3. A transdermal drug delivery system and a method of preparation thereof. Indian Patent Application No.: 202511000029, submitted January 2025.
    4. Milk Protein and Aloe Vera based composite tablet thereof. Indian Patent application submitted. August 2023. Patent Application No.: 202311057324
    5. Dental Fluoride Varnish Incorporated with Tulsi Extract. Indian Patent application. Patent Application Submitted with Ref: No. IPRTTC/2023-24/79

 Post Graduate Thesis Supervision: M.Pharm: 33 and IDD: 11

PhD:

As Supervisor : 2 (submitted) 3(ongoing);

Co-Supervisor: 1(ongoing) and 1(Submitted) Faculty of Ayurvedic Medical Science); and 1(ongoing,)Department of Food and Dairy Sciences)

MD:

Co-guide: MD (Ayurved): 2 (Submitted); MD (Dental): 1 ongoing and 2 (submitted)

British Society for Nanomedicine, UK

Association of Pharmaceutical Teachers of India

Asian Council of Science Editors, Asia

Society for Pharmaceutical Education and Research, India

Multiple Emulsions Technology and Nanotechnology 

Nano-drug Drug Delivery Systems

Alzheimer’s Disease and Lung disorders/ cancer

3D Bioprinting  for regenerative therapy

AI and ML in Formulation Development

 Awards

 1.   M.Pharm, GATE scholarship, University Grants Commission, New Delhi

2.   Best participant Award at 52nd Orientation Course (2009), UGC, Academic Staff College, BHU, Varanasi

3.   DST-  Travel  Award  for  attending  International  Conference  on  Nanotechnology  in Medicine (NanoMed12), University College London, London, UK

4.   Best Poster Award at Pharmaceutical Summit and Expo, 2015 New Delhi, India

5.   First prize in oral presentation at TRANSPIRE-2014, Kurnool, Andhra Pradesh, India

6.   Outstanding Researcher In Pharmaceutics, Venus International Foundation,  2018

7.  1st prize on Institute Day, IIT (BHU),  for Model presentation on Waste Management, 2018