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Dr. Sairam Krishnamurthy

Professor
Department of Pharmaceutical Engineering and Technology
Phone No(s): 9935509199
Email: ksairam.phe@iitbhu.ac.in
Area of Interest: Pharmacology, Neuroscience, Mitochondrial medicine and Biomaterials.
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  1. Prajapati SK, Ahmed S, Rai V, Gupta SC, Krishnamurthy S (2024) Suvorexant improves mitochondrial dynamics with the regulation of orexinergic and mTOR activation in rats exhibiting PTSD-like symptoms  Journal of Affective disorders
  2. Prajapati SK,  Teja R,  Krishnamurthy S (2023) Inhibition of phosphodiesterase-4 mitigates stress-re-stress-paradigm induced mitochondrial perturbations in rats exhibiting PTSD-like symptoms. Neuroscience and Behavioral Physiology, 1-17
  3. Bajad NG, Singh RB,. Gajendra T.A , Gutti G, Kumar A, Krishnamurthy S, Singh SK, (2024) Development of multi-targetable chalcone derivatives bearing N-aryl piperazine moiety for the treatment of Alzheimer's disease Bio-organic chemistry
  4. Kelsey Teeple, Prabha Rajput, Sara Scinto, Jenna Schoonmaker, Corrin Davis, Michayla Dinn, Mackenzie McIntosh, Sairam Krishnamurthy, Karen Plaut, Theresa Casey (2023) Impact of high-fat diet and exposure to constant light on reproductive competence of female ICR mice. Biology Open. Vol 12. Issue 10.
  5. Gutti G, Leifeld J, Kakarla R, Bajad NG, Ganeshpurkar A, Kumar A, Krishnamurthy S, Klein-Schmidt C, Tapken D, Hollmann M, Singh SK (2023) Discovery of triazole-bridged aryl adamantane analogs as an intriguing class of multifunctional agents for treatment of Alzheimer's disease. European Journal of Medicinal Chemistry. 259. 115670.
  6. Qadir A, Ganeshpurkar A, Singh SK, Krishnamurthy S (2023) Preparation, characterization, in-vitro and in-vivo pharmacokinetic evaluation of thermostable dimethyl fumarate cocrystals Journal of Pharmaceutical Sciences
  7. Alam Q, Ganeshpurkar A, Singh SK, Krishnamurthy S (2023)Novel Gastroprotective and Thermostable Cocrystal of Dimethyl Fumarate: Its Preparation, Characterization, and In Vitro and In Vivo Evaluation. ACS Omega
  8. Ramakrishna K, Sinku S, Majumdar S, Singh N, Gajendra TA, Rani A, Krishnamurthy S (2023) Indole-3-carbinol ameliorated the thioacetamide-induced hepatic encephalopathy in rats. Toxicology, 153542
  9. J Kumar, G Shankar, S Kumar, J Thomas, N Singh, S Srikrishna, J Satija, Krishnamurthy S , Modi G, Mishra SK. (2023). Extraction, isolation, synthesis, and biological evaluation of novel piperic acid derivatives for the treatment of Alzheimer’s disease. Molecular Diversity, 1-20
  10. Waiker D Kumar, Verma A, Akhilesh,  Gajendra TA, Singh N, Roy A, Dilnashin H, Tiwari V, Trigun SK, Singh SP, Krishnamurthy S, Lama P, Davisson VJ,  Shrivastava SK. (2023) Design, Synthesis, and Biological Evaluation of Piperazine and N-Benzylpiperidine Hybrids of 5-Phenyl-1, 3, 4-oxadiazol-2-thiol as Potential Multitargeted Ligands for Alzheimer’s Disease Therapy. ACS Chemical Neuroscience
  11. Tripathi P, Ganeshpurkar A, Singh SK, Krishnamurthy S (2023) Identification of novel glucocerebrosidase chaperone for potential treatment of Parkinson's disease: An approach using in silico virtual screening, molecular docking and molecular dynamics, and in vitro studies.  International Journal of Biological Macromolecules. 228, 453-466.
  12. Bhanukiran K, Singh R,  Gajendra TA,  Ramakrishna K,  Singh SK,  Krishnamurthy S, Ashok Kumar,  Hemalatha S (2023)Vasicinone, a pyrroloquinazoline alkaloid from Adhatoda vasica Nees enhances memory and cognition by inhibiting cholinesterases in Alzheimer's disease. Phytomedicine Plus .Available online 30 March 2023, 3 (2), 100439. 
  13. Rajput P, Krishnamurthy S (2023) Standardization and validation of novel ex-vivo method for mitochondrial bioenergetics using mitochondrial modulators. Journal of Pharmacological and Toxicological Methods. 119, 107209
  14. Waiker DK, Verma A, Saraf P, Gajendra TA, Krishnamurthy S, Chaurasia RN, Shrivastava SK (2023) Development and Evaluation of Some Molecular Hybrids of N-(1-Benzylpiperidin-4-yl)-2-((5-phenyl-1,3,4-oxadiazol-2-yl)thio) as Multifunctional Agents to Combat Alzheimer’s Disease. ACS Omega. 8 (10), 9394-9414.
  15. Rajput P, Aryal UK, Bhide K, Minor RC, Krishnamurthy S, Casey TM (2023) Characterization of sow milk N-linked glycoproteome over the course of lactation. Journal of Animal Science 101, skac426
  16. Ganeshpurkar A; Singh, R; Tripathi P; Qadir A; Krishnamurthy S; Kumar A; Singh S (2023) Effect of sulfonamide derivatives of phenylglycine on scopolamine‐induced amnesia in rats.Ibrain. 9 (1), 13-31
  17. Bhanukiran K, Gajendra T.A., Krishnamurthy S, Singh SK, Hemalatha S (2023) Discovery of multi-target directed 3-OH pyrrolidine derivatives through a semisynthetic approach from alkaloid vasicine for the treatment of Alzheimer’s disease . European Journal of Medicinal Chemistry Volume 249, 5 March 2023, 115145.
  18. Tekam CKS, Majumdar S, Kumari P, Prajapati SK, Sahi AK, Shinde S Richa Singh, Samaiya PK, Patnaik R,  Krishnamurthy S, Mahto SK (2023) Effects of ELF-PEMF Exposure on Spontaneous Alternation, Anxiety, Motor Co-ordination and Locomotor Activity of Adult Wistar Rats and Viability of C6 (Glial) Cells in Culture. Toxicology, 485, 153409
  19. Ramakrishna K, Krishnamurthy S (2023) Indole‐3‐carbinol ameliorated the neurodevelopmental deficits in neonatal anoxic injury in rats. International Journal of Developmental Neuroscience. 83 (1), 31-43.
  20. Kakarla R, Singh SK, Krishnamurthy S (2022) Diindolylmethane Ameliorates Ischemic Stroke-Induced Brain Injury by Peripheral and Central Mechanisms.. Current Neurovascular Research
  21. Majumdar S,  Krishnamurthy S (2022) In vivo toxicological evaluation of  barium-doped bioactive glass in rats. Ceramics International. 48 (22), 33288-33305
  22. Manzoor S , Prajapati SK , Majumdar  S, Khurana S, Krishnamurthy S,  Hoda N (2022) Pharmacological investigations of selected phenyl sulfonyl-pyrimidine carboxylate multitarget-direct ligands for the treatment of Alzheimer's disease. ChemistrySelect. 7 (38), e202200975.
  23. Khare D, Majumdar S, Krishnamurthy S, DubeyA K (2022)  An in vivo toxicity assessment of piezoelectric sodium potassium niobate [NaxK1-xNbO3 (x= 0.2–0.8)] nanoparticulates towards bone tissue engineering approach.  Biomaterials Advances, 21308
  24. Kumar DN, Chaudhuri A, Dehari D,  Shekher A,. Gupta SC, Majumdar S, Prajapati SK, Krishnamurthy S,  Singh S, Kumar D, Agrawal  AK(2022) Combination therapy comprising paclitaxel and 5-fluorouracil by using folic acid functionalized bovine milk exosomes improves the therapeutic efficacy against breast cancer. Life-1842157. Online.
  25. Tripathi P, Ganeshpurkar A, Singh SK, Krishnamurthy S (2022) Generation of wild-type rat Glucocerebrosidase homology modeling: Identification of putative interactions site and mechanism for chaperone using combined in-silico and in-vitro studies. Bio-organic chemistry. 105871
  26. Ramakrishna, K., Jain SK, Krishnamurthy, S., (2022) Pharmacokinetic and pharmacodynamic properties of Indole-3-carbinol in experimental focal ischemic injury. European Journal of Drug Metabolism and Pharmacokinetics. 1-13
  27. Ramakrishna, K., Singh, N., Krishnamurthy, S., (2022) Diindolylmethane ameliorates platelet aggregation and thrombosis: In silico, in vitro, and in vivo studies, European Journal of Pharmacology, 919, 174812.
  28. Ramakrishna, K., Krishnamurthy, S., Indole-3-carbinol ameliorated the Isoproterenol induced myocardial infarction via multimodal mechanisms in Wistar rats. 1-6. Natural product Research
  29. Alam, Q., Krishnamurthy, S., (2022) Dihydroquercetin ameliorates LPS-induced neuroinflammation and memory deficit, Current Research in Pharmacology and Drug Discovery, doi: https://doi.org/10.1016/j.crphar.2022.100091
  30. Vig R, Bhadra F, Gupta SK, Prajapati SK, Krishnamurthy S, Vasundhara M (2022) Neuroprotective effects of quercetin produced by an endophytic fungus Nigrospora oryzae isolated from Tinospora cordifolia. Journal of Applied Microbiology. 132 (1), 365-380
  31. Majumdar S, Gupta S, Krishnamurthy S (2022) Multifarious applications of bioactive glasses in soft tissue engineering, Biomaterials Science 9 (24), 8111-8147
  32. Majumdar S, Gupta S, Prajapati SK, Krishnamurthy S (2021) Neuro-nutraceutical potential of Asparagus racemosus: a review. Neurochemistry International. 145, 105013
  33. Yadav S, Ali A, Krishnamurthy S, Singh P, Pyare R (2021) In-vitro analysis of bioactivity, hemolysis, and mechanical properties of Zn substituted Calcium Zirconium silicate (baghdadite). Ceramics International. 2021 Jun 1;47(11):16037-53
  34. Gupta S, Majumdar S, Krishnamurthy S (2021). Bioactive glass: A multifunctional delivery system. Journal of Controlled Release. 335, 481-497
  35. Samaiya PK, Krishnamurthy S, Kumar A (2021). Mitochondrial dysfunction in perinatal asphyxia: role in pathogenesis and potential therapeutic interventions. Molecular and Cellular Biochemistry. 476 (12), 4421-4434.
  36. Bhattacharjee A, Prajapati SK, Krishnamurthy S (2021). Supplementation of taurine improves ionic homeostasis and mitochondrial function in the rats exhibiting post-traumatic stress disorder-like symptoms. European Journal of Pharmacology. 908, 174361
  37. Manzoo S, Prajapati SK, Majumdar S, Raza MK, Pal K, Rashid H, Prajapati SK, Krishnamurthy S and Hoda N(2021)  Discovery of new phenyl sulfonyl-pyrimidine carboxylate derivatives as the potential multi-target drugs with effective anti-Alzheimer's action: Design, Synthesis, Crystal structure and In-vitro biological evaluation. European Journal of Medicinal Chemistry.  215, 113224.
  38. Prajapati SK, Krishnamurthy S (2021) Development and treatment of cognitive inflexibility in sub-chronic stress–re-stress (SRS) model of PTSD. Pharmacological Reports 73 (2), 464-479.
  39. Prajapati SK, Krishnamurthy S (2020) Non-selective orexin-receptor antagonist attenuates stress-re-stress-induced core PTSD-like symptoms in rats: Behavioural and neurochemical analyses. Behavioural Brain Research 399, 113015
  40. Majumdar S, Hira SK, Tripathi H, Kumar AS, Manna PP, Singh SP, Sairam Krishnamurthy Krishnamurthy S, (2020) Synthesis and characterization of barium-doped bioactive glass with potential anti-inflammatory activity. Ceramics International, 47(5), 7143-7158
  41. Firdaus Z, Singh N, Prajapati SK, Krishnamurthy S, Singh TD (2020) Centella asiatica prevents D-galactose-Induced cognitive deficits, oxidative stress and neurodegeneration in the adult rat brain, Drug and Chemical Toxicology, 1-10.
  42. Sharma S, Dixit P, Krishnamurthy S, Sahu AN (2020) Amelioration of cisplatin induced nephrotoxicity by Phyla nodiflora (L.) Greene NISCAIR-CSIR, India.
  43. Gupta SK, D Garabadu D, Singh M B, Srivas S, Tomar MS, Mesharam MK , Thakur MK and Krishnamurthy S (2020) Sub-chronic exposure of electromagnetic radiation (EMR)-2450 MHz exacerbates depressive-like symptoms in rats with changes in cerebral hemodynamics. Biomedical and Environmental Sciences
  44. Prajapati SK, Singh N, Garabadu D, Krishnamurthy S (2020) A novel stress re-stress model: Modification of re-stressor cue induces long-lasting post-traumatic stress disorder-like symptoms in rats. International Journal of Neuroscience, 1-21
  45. Prajapati SK, Bhaseen S, Krishnamurthy S, Sahu AN (2020) Neurochemical Evidence of Preclinical and Clinical Reports on Target-Based Therapy in Alcohol Used Disorder Neurochemical Research, 45 (2), 491-507
  46. Hossain S, Yadav SK, Majumdar S,, Krishnamurthy S, Pyare R, Roy P.K. (2020) A comparative study of physico-mechanical, bioactivity and hemolysis properties of pseudo-wollastonite and wollastonite glass-ceramic synthesized from solid wastes. Ceramics International 46 (1), 833-843.
  47. Mishra A, Krishnamurthy S (2020) Neurorestorative effects of sub-chronic administration of ambroxol in rodent model of Parkinson’s disease Naunyn-Schmiedeberg's Archives of Pharmacology,  Naunyn-Schmiedeberg's Archives of Pharmacology 393 (3), 429-444 (IF-2.058)
  48. Balavigneswaran CK, Venkatesan R, Karuppiah PS, Kumar G, Paliwal P, Krishnamurthy S, BKadalmani B, Mahto SK, MisraN  (2019) Silica release from silane cross-linked gelatin based hybrid scaffold affects Cell proliferation, ACS Applied Bio Materials
  49. Swetha R, Kumar D, Gupta SK, Ganeshpurkar A,  Singh R, Gutti G, Dileep Kumar, Srabanti Jana, Krishnamurthy S, Singh SK (2019) Multifunctional hybrid sulfonamides as novel therapeutic agents for Alzheimer’s disease. Future Medicinal Chemistry 11 (24), 3161-3178.
  50. Tripathi A, Choubey PK, Sharma P, Seth A, Tripathi PN, Tripathi MK, Prajapati SK, Krishnamurthy S, Shrivastava SK (2019) Design and development of molecular hybrids of 2-pyridylpiperazine and 5-phenyl-1, 3, 4-oxadiazoles as potential multifunctional agents to treat Alzheimer's disease European Journal of Medicinal Chemistry 183, 111707
  51. Gutti G, Kakarla R, Kumar D, Beohar M, Ganeshpurkar A, Kumar A, Krishnamurthy S, Singh Sk(2019) Discovery of novel series of 2-substituted benzo [d] oxazol-5-amine derivatives as multi-target directed ligands for the treatment of Alzheimer's disease. European journal of medicinal chemistry 182, 111613
  52. Prajapati SK, Dangi DS, Krishnamurthy S (2019) Repeated caffeine administration aggravates post-traumatic stress disorder-like symptoms in rats. Physiology & Behavior, 211, 112666
  53. Gupta S K, Patel SK, Tomar MS, Singh SK, Mesharam MK and Krishnamurthy S (2019)  Long-term exposure of 2450 MHz Electromagnetic radiation induces stress and anxiety like behavior in rats, Neurochemistry International.
  54. Mishra A, Krishnamurthy S (2019) Rebamipide Mitigates Impairments in Mitochondrial Function and Bioenergetics with α- Synuclein Pathology in 6-OHDA-Induced Hemiparkinson’s Model in Rats, Neurotoxicity research, 1-21.
  55. Sharma P, Kumari A, Gulati A, Krishnamurthy S, Hemalatha S (2019) Chrysin isolated from Pyrus pashia fruit ameliorates convulsions in experimental animals. Nutritional neuroscience 22(8), 569-577
  56. Gutti G, Kumar D, Paliwal P, Ganeshpurkar A, Lahre K, Kumar A, Krishnamurthy S, Singh S K (2019)  Development of pyrazole and spiropyrazoline analogs as multifunctional agents for treatment of Alzheimer’s disease Bioorganic Chemistry, 103080
  57. Kumar G, Mukherjee S, Paliwal P, Singh S S, Birla Ha, Singh SP , Krishnamurthy S, Patnaik R Neuroprotective effect of chlorogenic acid in global cerebral ischemia-reperfusion rat model Naunyn-Schmiedeberg's archives of pharmacology, 1-17.
  58. Mishra P, Sharma P, Tripathi PN, Gupta SK, Srivastava P, Seth A, Tripathi A, Krishnamurthy S, Shrivastava SK (2019) Design and Development of 1, 3, 4-Oxadiazole Derivatives as Potential Inhibitors of Acetylcholinesterase to Ameliorate Scopolamine-Induced Cognitive Dysfunctions. Bioorganic Chemistry, 103025.
  59. Arepalli S K, Tripathi H, Manna PP, Pankaj P, Krishnamurthy S, Shashikant CU Patne, Pyare R, Singh SP (2019) Preparation and in vitro investigation on bioactivity of magnesia-contained bioactive glasses. Journal of the Australian Ceramic Society, 55 (1), 145-155
  60. Arepalli S K, Tripathi H, Manna PP, Pankaj P, Krishnamurthy S, Shashikant CU Patne, Pyare R, Singh SP (2018)  Enhanced in vivo biocompatibility of magnesia-contained bioactive glasses Journal of the Australian Ceramic Society, 55 (2), 337-342
  61. Kumar G, Paliwal P, Mukherjee S, Patnaik N, Krishnamurthy S, Patnaik R (2019) Pharmacokinetics and Brain Penetration Study of Chlorogenic Acid. Xenobiotica, 49 (3), 339-345.
  62. Kumar D, Gupta SK,  Ganeshpurkar A, Singh R, Kumar D,  DasN, Krishnamurthy S, Singh  SK(2019) Biological profiling of piperazinediones for the management of anxiety. Pharmacology Biochemistry and Behavior 176, 63-71
  63. Sharma P, Tripathi A,  Tripathi PN, Prajapati SK, Seth A, Tripathi MK, Srivastava P, Tiwari V, Krishnamurthy S, Shrivastava SK (2019) Design and development of multitarget-directed N-Benzylpiperidine analogs as potential candidates for the treatment of Alzheimer's disease. European Journal of Medicinal Chemistry
  64. Tripathi A,Dubey PK, Pandey VK, Tripathi G, Hazarika S, Krishnamurthy S, Sahu A. N. (2019). Di-(2-ethylhexyl) phthalate (DEHP) and ovarian physiology: A brief review of therapeutic potential of Asparagus racemosus on DEHP- induced toxicity. Journal of Medicinal Plant and Herbal Therapy Research 6, 9-18.
  65. Mishra A, Chandravanshi LP, Trigun Sk and Krishnamurthy S (2018) Ambroxol modulates 6-Hydroxydopamine-induced temporal reduction in Glucocerebrosidase (GCase) enzymatic activity and Parkinson’s disease symptoms. Biochemical Pharmacology. 155, 479-493
  66. Mahanta AK, Senapati S, Maiti P, Paliwal P, Krishnamurthy S, Hemalatha S (2018) Nanoparticle Induced Controlled Drug Delivery using Chitosan based Hydrogel and Scaffold: Application to Bone Regeneration. Molecular pharmaceutics 16 (1), 327-338
  67. Kumar B, Dwivedi AR, Sarkar B, Gupta SK, Krishnamurthy S, Mantha AK, Prakash J, and Kumar V (2018) 4, 6-Diphenylpyrimidine Derivatives as Dual Inhibitors of Monoamine Oxidase and Acetylcholinesterase for the Treatment of Alzheimer’s Disease. ACS Chem. Neurosci., DOI: 10.1021/acschemneuro.8b00220 •
  68. Pandey A, Joshi A, Mishra S, Krishnamurthy S, Hemalatha S (2018) Antinociceptive, anti inflammatory and antiarthritic activity of ethanol root extract and fraction of Aganosma dichotoma (Roth) K. Schum. Indian J Exp Biol. Vol.56(09) [September 2018]. http://nopr.niscair.res.in/handle/123456789/44999.
  69. Paliwal P, Kumar AS, Tripathi H, Singh SP, Patne SCU, Krishnamurthy S (2018) Pharmacological application of barium containing bioactive glass in gastro-duodenal ulcers. Materials Science and Engineering: C.  92, 424-434
  70. Reddy NR, Krishnamurthy S (2018) Repeated olanzapine treatment mitigates PTSD like symptoms in rats with changes in cell signaling factors. Brain research bulletin. 140, 365-377
  71. Hussain Y, Krishnamurthy S     (2018)  Piracetam attenuates binge eating disorder related symptoms in rats. Pharmacol Biochem Behav. 169, 35-47.
  72. Paliwal P, Chauhan G, Gautam D, Dash D, Patne SCU, Krishnamurthy S (2018) Indole-3-carbinol improves neurobehavioral symptoms in a cerebral ischemic stroke model Naunyn-Schmiedeberg's archives of pharmacology, 391 (6), 1-13.
  73. Gupta SK, Krishnamurthy S (2018) Electromagnetic radiation 2450 MHz exposure causes cognition deficit with mitochondrial dysfunction and activation of intrinsic pathway of apoptosis in rats. Journal of biosciences.
  74. Devendra Kumar, Sukesh K Gupta, Ankit Ganeshpurkar, Gopichand Gutti, Krishnamurthy S Gyan Modi, Sushil Kumar Singh (2018) Development of Piperazinediones as dual inhibitor for treatment of Alzheimer's disease. European Journal of Medicinal Chemistry 150, 87-101
  75. Samaiya PK, Narayan G, Kumar A, Krishnamurthy S (2018) 2, 4 dinitrophenol attenuates mitochondrial dysfunction and improves neurobehavioral outcomes post-anoxia in neonatal rats. Neurotoxicity Research 1-16 (DOI: 10.1007/s12640-018-9873-7)
  76. Tripathi RKP, Sasi V M, Gupta SK, Krishnamurthy S, Ayyannan SR (2018). Design, synthesis, and pharmacological evaluation of 2-amino-5-nitrothiazole derived semicarbazones as dual inhibitors of monoamine oxidase and cholinesterase: effect of the size of aryl binding site. Journal of Enzyme Inhibition and Medicinal Chemistry 33 (1), 37-57.
  77. Paliwal P, Dash D, Krishnamurthy S (2018) Pharmacokinetic study of Piracetam in Focal Cerebral Ischemic rats. European Journal of Drug metabolism and pharmacokinetics  43 (2), 205-213.
  78.  Kumar S, Mishra A, Krishnamurthy S (2017) Purinergic Antagonism Prevents Mitochondrial Dysfunction and Behavioral Deficits Associated with Dopaminergic Toxicity Induced by 6-OHDA in Rats. Neurochemical Research,  42 (12),1-17.(IF-2.581)
  79. Tripathi A, Paliwal P, Krishnamurthy S (2017) Piracetam Attenuates LPS-Induced Neuroinflammation and Cognitive Impairment in Rats. Cellular and Molecular Neurobiology, 37 (8),1-14. (IF-2.506)
  80. Prajapati SK, Garabadu D, Krishnamurthy S (2017) Coenzyme Q10 Prevents Mitochondrial Dysfunction and Facilitates Pharmacological Activity of Atorvastatin in 6-OHDA Induced Dopaminergic Toxicity in Rats. Neurotoxicity Research, 31 (4),1-15.
  81. Samaiya PK, Narayan G, Kumar A, Krishnamurthy S (2017) Tempol (4 hydroxy-tempo) inhibits anoxia-induced progression of mitochondrial dysfunction and associated neurobehavioral impairment in neonatal rats. Journal of the Neurological Sciences, 375, 58-67.
  82. Garabadu D, Krishnamurthy S (2017) Metformin attenuates hepatic insulin resistance in type-2 diabetic rats through PI3K/Akt/GLUT-4 signalling independent to bicuculline-sensitive GABAA receptor stimulation. Pharmaceutical Biology 55 (1), 722-728.
  83. Kushwah S, Kumar A, Basu S, Krishnamurthy S, Kumar A (2017) Comparison of cerebrospinal fluid Cytochrome-c and Caspase-9 as biomarkers for newborns with hypoxic ischemic encephalopathy with non-asphyxiated babies and follow up of these biomarkers after day 7. International Journal of Research in Medical Sciences 3 (8), 2034-2040.
  84. Samaiya PK, Narayan G, Kumar A, Krishnamurthy S (2016) Neonatal anoxia leads to time dependent progression of mitochondrial linked apoptosis in rat cortex and associated long term sensorimotor deficits.  International Journal of Developmental Neuroscience. Aug;52:55-65.
  85. Tripathi RKP, Krishnamurthy S, and Ayyannan  SR(2016) Discovery of 3-Hydroxy-3-phenacyloxindole Analogues of Isatin as Potential Inhibitors of Monoamine Oxidase. ChemMedChem. 11 (1), 119-132
  86. Garabadu D, Shah A, Singh S, Krishnamurthy S (2015) Protective effect of eugenol against restraint stress-induced gastrointestinal dysfunction: Potential use in irritable bowel syndrome. Pharmaceutical biology 53 (7), 968-974
  87. Garabadu D, Ahmad A, Krishnamurthy S (2015) Risperidone Attenuates Modified Stress–Re-stress Paradigm-Induced Mitochondrial Dysfunction and Apoptosis in Rats Exhibiting Post-traumatic Stress Disorder-Like Symptoms. Journal of Molecular Neuroscience, 56 (2), 1-14. (IF-2.757)
  88. Samaiya PK, Krishnamurthy S (2015) Characterization of mitochondrial bioenergetics in neonatal anoxic model of rats. Journal of bioenergetics and biomembranes, 47 (3),1-6.
  89. Garabadu D, Reddy BCMH, Krishnamurthy S, (2015), Citalopram Protects Against Cold-Restraint Stress-Induced Activation of Brain-Derived Neurotrophic Factor and Expression of Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells in Rats Journal of Molecular Neuroscience, 55 (2), 355-366 .
  90. Geed M, Garabadu D, Ahmad A and Krishnamurthy S (2014) Silibinin pretreatment attenuates biochemical and behavioral changes induced by intrastriatal MPP+ injection in rats. Pharmacol. Biochem. Behav. 117,  92–103.
  91. Garabadu D, Krishnamurthy S (2014)  Asparagus racemosus attenuates Anxiety-Like Behavior in Experimental Animal Models. Cellular and molecular neurobiology 34 (4), 511-521.
  92. Das N, Garabadu D, Banerjee AG, Krishnamurthy S, Shrivastava SK. (2014) Synthesis and pharmacological evaluation of some N3-aryl/heteroaryl-substituted 2-(2-chlorostyryl)-6, 7-dimethoxy-quinazolin-4 (3H)-ones as potential anticonvulsant agents. Medicinal Chemistry Research, 1-10.
  93. Garabadu D, Shah A, Singh S, Krishnamurthy S. (2014) Protective effect of eugenol against restraint stress-induced gastrointestinal dysfunction: Potential use in irritable bowel syndrome, Pharmaceutical Biology, 1-7.
  94. Joshi R, Garabadu D, Teja GR, Krishnamurthy S. (2014) Silibinin ameliorates LPS-induced memory deficits in experimental animals. Neurobiology of learning and memory, Dec;116:117-31.3.
  95. D Laloo, SK Prasad, Sairam Krishnamurthy, S Hemalatha. (2014) Gastroprotective activity of polyphenolic-rich extract of Potentillamooniana, Pharmaceutical Biology 52 (12), 1532-1542
  96. Garabadu D, Krishnamurthy S. (2014) Diazepam Potentiates the Antidiabetic, Antistress and Anxiolytic Activities of Metformin in Type-2 Diabetes Mellitus with Cooccurring Stress in Experimental Animals, BioMed Research International.
  97.  Nandi MK, Garabadu D, Krishnamurthy S, Singh TD, Singh VP., (2014) Argyreiaspeciosa attenuates streptozotocine-nicotinamide-induced hyperglycemia in experimental animals of type-2 diabetes mellitus..Der Pharma Chemica 6 (5).
  98. Kumar M, Prasad SK, Krishnamurthy S, Hemalatha S., (2014)  Antihyperglycemic Activity of HouttuyniacordataThunb. inStreptozotocin-Induced Diabetic Rats. Advances in pharmacological sciences.
  99. Sahu Alakh N, Hemalatha S, Krishnamurthy S. (2014) Phyto-pharmacological review of mesuaferrea linn. International Journal of Phytopharmacology, 5(1), 6-14.
  100. Manmath VPS. Nandi K, Garabadu D, Krishnamurthy S, Trayambak D (2014) Methanolic fruit extract of Sesbania grandiflora exhibits anti-hyperglycemic activity in experimental type-2 diabetes mellitus model. Annals of Biological Research 5 (9), 50-58.
  101. Krishnamurthy S, Garabadu D and Joy KP. (2013) Risperidone ameliorates post traumatic stress disorder-like symptoms in modified stress re-stress model.Neuropharmacology, 75, 62–77.
  102.  Laloo D, Prasad SK, Krishnamurthy S, Hemalatha  S (2013) Gastroprotective activity of ethanolic root extract of Potentillafulgens Wall. ex Hook J Ethnopharmacology, 146 (2),505–514.
  103. Sahu Alakh N, Hemalatha S and Krishnamurthy S. (2013) Quality control studies of Argyreiaspeciosa sweet leaves. Int. J. Res. Ayurveda Pharm. 4(4), July-Aug, 495-498.
  104.  SahuAlakh N, Hemalatha S and Krishnamurthy S. (2013) HPTLC fingerprinting and in vitro antioxidant studies of Argyreiaspeciosa sweet leaves and mesuaferrealinn. flowers. Int. J. Res. Ayurveda Pharm. 4(4), July-Aug, 499-502.
  105. SahuAlakh N, Hemalatha S and Krishnamurthy S. (2013). Quality Control Studies of MesuaferreaLinn. Flowers. International Journal of Herbal Medicine. 1(2), 124-130.
  106. SahuAlakh N, Hemalatha S, Krishnamurthy S. (2013) Gastric-ulcer protective activity of argyreiaspeciosasweet leaves)  International Journal of Biological & Pharmaceutical Research. 2013; 4(12): 1182-1186,
  107. Sahu A N, Hemalatha S, Krishnamurthy S. (2013) Quantitative Phytochemical and Heavy Metal Estimation of MesuaferreaFlowers and ArgyreiaspeciosaLeaves  Int. J. Pharm. Sci. Rev. Res., 22(2), Sep – Oct 2013( 49), 276-278.
  108.  Patel DK, R Kumar, Krishnamurthy S, Hemalatha S (2013)
    Hybanthusenneaspermus(L.) F. Muell: a concise report on its phytopharmacological aspects. Chinese journal of natural medicines 11 (3), 199-206.
  109. Krishnamurthy S, Garabadu D, Reddy NR (2013) Asparagus racemosus modulates the hypothalamic-pituitary-adrenal axis and brain monoaminergic systems in rats. Nutritional neuroscience. 16(6), 255-61.
  110. DamikiLaloo,  Satyendra K. Prasad, Krishnamurthy S, Siva Hemalatha(2013) Gastroprotective activity of ethanolic root extract of Potentillafulgens Wall. ex Hook J Ethnopharmacology, 146 (2),505–514.
  111. Krishnamurthy S, Garabadu D and Joy KP. (2013) Risperidone ameliorates post traumatic stress disorder-like symptoms in modified stress re-stress model.Neuropharmacology, 75, 62–77.
  112. PatelDK  Kumar R.. Krishnamurthy S.Hemalatha S (2013) Advances in Plant Pharmacology of Hemiphyllum. Chinese Natural Medicine 03,004. 
  113. Patel DK, Krishnamurthy S, Hemalatha S (2013) Evaluation of glucose utilization capacity of bioactivity guided fractions of Hybanthus enneaspermus and Pedalium murex in isolated rat hemidiaphragm. Journal of Acute Disease 2 (1), 33-36.
  114. Patel D. K., Kumar R., Krishnamurthy S., S. Hemalatha.  (2012) Aphrodisiac activity of ethanolic extract of Pedalium murex Linn fruit. Asian Pacific Journal of Tropical Biomedicine, (2012) Asian Pacific Journal of Tropical Biomedicine, S1568-S1571.
  115. Patel D. K., Kumar R., Kumar M., Krishnamurthy S, Hemalatha S.  (2012) Evaluation of aldose reductase inhibitory potential of different fraction of Hybanthusenneaspermuslinn f. muell. Asian Pacific Journal of Tropical Biomedicine, 2(2): 134-139.
  116. Kumar R, Patel DK, Prasad SK, Krishnamurthy S,Hemalatha S. (2012) Antidiabetic activity of alcoholic root extract of Caesalpiniadigynain streptozotocin-nicotinamide induced diabetic rats. Asian Pacific Journal of Tropical Biomedicine S934-S940.
  117. Patel DK, Kumar R, Krishnamurthy S, Hemalatha, S (2012)
    Pharmacologically tested aldose reductase inhibitors isolated from plant sources—A concise report.Chinese Journal of Natural Medicines 10 (5), 388-400.
  118. Patel DK, Krishnamurthy S, Hemalatha S (2012)
    Evaluation of glucose utilization capacity of bioactivity guided fractions of Hybanthusenneaspermus and Pedalium murex  in isolated rat hemidiaphragm. Journal of Acute Disease 2 (1), 33-36.
  119. Laloo D, Kumar M, Prasad SK, Krishnamurthy S, Hemalatha S (2012) Gastroprotective activity of the alcoholic root extract of Potentilla fulgens wall. Reviews on clinical pharmacology and medicinal therapy.(10) 2.
  120. Bithu BS, Reddy NR, Prasad SK, Krishnamurthy S, Hemalatha S (2012) Prosopis cineraria: A potential nootropic agent. Pharmaceutical Biology 50 (10), 1241-1247.(IF-1.206).
  121. Surapaneni DK, Adapa SR, Preeti K, Teja GR, Veeraragavan M, Krishnamurthy S. (2012)  Shilajit attenuates behavioral symptoms of chronic fatigue syndrome by modulating the hypothalamic-pituitary-adrenal axis and mitochondrial bioenergetics in rats. J Ethnopharmacol, Aug 30;143(1):91-9.
  122. Garabadu D, Shah A, Ahmad A, Joshi V, Saxena B, Palit G, Krishnamurthy S.(2011) Eugenol as an Anti-Stress Agent: Modulation of Hypothalamic-Pituitary-Adrenal Axis Activity and Brain Monoaminergic systems. Stress. Mar;14(2):145-55.
  123. Saxena B,  Krishnamurthy S, Singh S. (2011) Gastroprotective potential of risperidone, an atypical antipsychotic, against stress and pyloric ligation induced gastric lesions.ChemBiol Interact. Apr 25;190(2-3):155-64.
  124. Reddy NR, Krishnamurthy S, Chourasia TK, Kumar A, Joy KP. (2011) Glutamate antagonism fails to reverse mitochondrial dysfunction in late phase of experimental neonatal asphyxia in rats.Neurochem Int. Apr;58(5):582-90.
  125. Krishnamurthy S, GarabaduD, Reddy R and Joy KP. (2011) Risperidone in ultra low dose protects against stress in the rodent cold restraint model by modulating stress pathways.   Neurochem. Res.  36 (10) 1750-1758.
  126. Meena J,Ojha R, Muruganandam  AV and Krishnamurthy S. (2011) Asparagus racemosus competitively inhibits in vitro the acetylcholine and monoamine metabolizing enzymes. Neurosci.Lett.  503(1),  6-9.
  127. Patel DK, Kumar R, Prasad SK, Krishnamurthy S, Hemalatha S. (2011) Antidiabetic and in vitro antioxidant potential of Hybanthusenneaspermuslinn f. muell in streptozotocin-induced-diabetic rats. Asian Pacific Journal of Tropical Biomedicine 316-322.
  128. Kumar R. Patel, D. K,.Laloo D, Krishnamurthy S, Hemalatha S. (2011) Inhibitory effect of two Indian medicinal plants on aldose reductase of rat lens an in vitro study. Asian Pacific Journal of Tropical Medicine, 4, ( 9), September, Pages 694-697.
  129. Patel D. K., Prasad S. K, Krishnamurthy S, Hemalatha., S. (2011) Aldose reductase inhibitory principles from the whole plant of Hybanthusenneaspermus (Linn) F. Muell. Asian Pacific Journal of Tropical Disease , 2 (1),S-165-S169.
  130. Patel D.K., Kumar R, Krishnamurthy S., Hemalatha S. (2011) Aldose reductase inhibitory activity of alcoholic extract of Pedalium murex Linn. Asian Pac J Trop Biomed, 2, (1), Supplement, January, S265–S269.
  131. Kumar R, Dinesh K. Patel, Satyendra K. Prasad, DamikiLaloo, Krishnamurthy S, Hemalatha S. (2011) Type 2 antidiabetic activity of bergenin from the roots of CaesalpiniadigynaRottler.Fitoterapia 83 (2),395-401.
  132.  Kumar R, Patel DK, Prasad SK, Krishnamurthy S, Hemalatha S. (2011) Antidiabetic activity of alcoholic leaves extract of AlangiumlamarckiiThwaites on streptozotocin–nicotinamide induced type 2 diabetic rats. Asian Pacific Journal of Tropical Medicine 4 (11), 904–909.
  133. Nickell JR, Krishnamurthy S, Norrholm S, Deaciuc G, Siripurapu KB, Zheng G, Crooks PA, Dwoskin LP.(2010) Lobelane Inhibits Methamphetamine-Evoked Dopamine Release via Inhibition of the Vesicular Monoamine Transporter-2.J PharmacolExpTher.Feb;332(2):612-21.
  134. Ohja R, Sahu AN, Muruganandam AV, Singh GK, Krishnamurthy S.(2010)Asparagus recemosus enhances memory and protects against amnesia in rodent models. Brain and Cognition.  Oct;74(1):1-9.
  135. Sahu A N, Hemalatha S, Krishnamurthy S, Laloo D and Patra A.  (2010) Quality Control Studies of Ochrocarpuslongifolius Flower Buds.   PHCOG J February ;Pharmacognosy Journal 2 (6) ,118-123.
  136. Sahu A N, Hemalatha S, Krishnamurthy S. (2010) Phytochemical quantitative estimation and pesticide residue determination of Mesua ferreaflowers. Journal of Medicinal and Aromatic Plant Sciences 32 (4)  187-192.
  137. Rao Ch.V, Vijayakumar M, Krishnamurthy S, Kumar V(2008) Antidiarrhoeal activity of the standardised extract of Cinnamomum tamala in experimental rats. J Nat Med(Tokyo) 2008 Oct;62(4):396-402.
  138. Gireesh KS, Debapriya G, Muruganadam AV, Joshi VK, Krishnamurthy S (2009). Antidepressant activity of Asparagus racemosus in animal models of depression. Pharmacol. Biochem. Behav. 2009 Jan;91(3):283-90
  139. Begum S A., Saxena B, Goyal M, Ranjan R,  Joshi VB, Rao Ch V, Krishnamurthy S, Mahendra Sahai. (2009) Study of anti-inflammatory, analgesic and antipyretic activities of seeds of Hyoscyamus niger and isolation of a new coumarinolignan. Fitoterapia Apr;81(3):178-84.
  140. Sullivan P, Krishnamurthy S, Pandya J, Rabchevsky AG (2007) Temporal characterization of mitochondrial bioenergetics and effect of mitochondrial targeted compounds in spinal cord injury. J. Neurotrauma 24:991-999.
  141.  Goel R K, Krishnamurthy S, Dorababu M, Prabha T and Rao  Ch V (2005) Effect of standardized extract of Ocimum sanctum Linn. on gastric mucosal offensive and defensive factors. Indian J Exp Biol 43:715-721.
  142. Krishnamurthy S, Hemalatha S, Kumar A, Srinivasan T, Ganesh J, Shankar M and Venkataraman S (2003) Evaluation of anti-diarrhoeal activity in seed extracts of Mangifera indica. J Ethnopharmacol 84:11-15.
  143. Krishnamurthy S, Priyambada S, Aryya NC and Goel RK (2003)  Anti-gastroduodenal ulcerogenic activity of Asparagus racemosus- an experimental, biochemical and histological study. J Ethnopharmacol 86:1-10. (1.269/2003).
  144. Goel RK, Krishnamurthy S, Travares IA and Raman A (2003) In vitro evaluation of Bacopa monniera on accumulation of prostaglandins and anti-Helicobacter pylori activity. Phytomedicine10:523-527.
  145. Krishnamurthy S, Saravanan KS, Banerjee R and Mohanakumar KP (2003) Non-steroidal anti-inflammatory drug sodium salicylate, but not diclofenac or celecoxib, protects against 1-methyl-4-phenyl pyridinium-induced dopaminergic neurotoxicity in rats. Brain Res 966:245-252.
  146. Bhattacharya SK, Bhattacharya A, Krishnamurthy S and Ghosal S (2002) Effect of bioactive tannoid principles of Emblica officinalis on ischemia-reperfusion induced oxidative stress on rat heart. Phytomedicine 9:171-174.
  147. Bhattacharya SK, Bhattacharya D, Krishnamurthy S and Ghosal S (2002) Effect of Withania somnifera glycowithanolides on rat model of tardive dyskinesia. Phytomedicine 9:167-170.
  148. Krishnamurthy S, Dorababu M , Goel RK and  Bhattacharya SK (2002) Antidepressant activity of standardized extract of Bacopa monniera in experimental models of depression in rats. Phytomedicine 9:207-211.
  149. Krishnamurthy S, Rao Ch.V, Dora Babu M, Agrawal VK and Goel RK (2002) Antiulcerogenic effect of methanolic extract of Emblica officinalis: an experimental study. J Ethnopharmacol 82:1-9. (
  150. Datla GK, Krishnamurthy S, Priyambada S, Debnath PK and Goel RK (2002)  Antiulcerogenic activity of Satavari mandur-an Ayurvedic herbo-mineral preparation. Indian J Exp Biol40:1173-1177.
  151. Rao Ch V, Krishnamurthy S and Goel RK (2001) Experimental evaluation of Emblica officinalis fruit on gastric ulcers and mucosal offensive and defensive factors in rats. Acta Pharmaceutica Turcica XLIII: 155-160.
  152. Krishnamurthy S, Rao CH V, Dora Babu M and Goel RK (2001) Prophylactic and curative effects of Bacopa monniera in gastric ulcer models. Phytomedicine 8:423-430.
  153. Sairam K, Rao Ch V and Goel RK (2001) Effect of Convolvulus pluricaulis Chois on gastric ulceration and secretion in rats. Indian J Exp Biol 39:350-354.
  154. Bhattacharya SK, Bhattacharya A, Das K, Muruganantham AV and Krishnamurthy S (2001) Further investigations on the antioxidant activity of Ocimum sanctum using different paradigms of oxidative stress in rats. Natural Remedies 1:1-13.
  155. Krishnamurthy S, Rao Ch V and Goel RK (2001) Effect of Centella asiatica Linn on physical and chemical factors induced gastric ulceration and secretion in rats. Indian J Exp Biol 39:137-142.
  156. Goel RK, Krishnamurthy S, Rao Ch V and Raman A (2001) Role of gastric antioxidant and anti-H.pylori activities in the antiulcerogenic activity of plantain banana (Musa sapientum Linn var. paradisiaca). Indian J Exp Biol 39:719-722.
  157. Bhattacharya SK, Bhattacharya A, Krishnamurthy S and Ghosal S (2000) Anxiolytic-antidepressant activity of Withania somnifera glycowithanolides: an experimental study. Phytomedicine 7:463-469.(0.779/2000).
  158. Rao Ch. V, Krishnamurthy S and Goel RK (2000) Experimental evaluation of Bacopa monniera on rat gastric ulceration and secretion. Indian J Physiol Pharmacol 44: 435-441.
  159. Agrawal AK, Rao Ch.V, Krishnamurthy S, Joshi VK and Goel RK (2000) Effect of Piper longum Linn, Zingiber officianalis Linn and Ferula species on gastric ulceration and secretion in rats. Indian J Exp Biol 38:994-998.
  160. Krishnamurthy S, Rao Ch V and Goel RK (2000) Effect of Ocimum sanctum Linn on peptic ulcers and gastric mucosal offensive and defensive factors. Biomedicine 20:260-267.
  161. Goel RK and Krishnamurthy S (2001) Antiulcer drugs from indigenous sources with emphasis on Musa sapientum, tamrabasma, Asparagus racemosus and Zingiber officinale. Indian J Pharmacol 34:100-110. 


D1.  

  1. “Evaluation of anti-depressant activity of Asparagus racemosus, IT(BHU); .2007-2008 (Role:PI)
  2. “Phytochemical Standardization and Pharmacological Evaluation of Some Potential Anti-Gastroduodenal Ulcer Plants” AICTE; ; Dec’2009-12 (CO-PI).
  3. “Pharmacological Evaluation of Atypical Anti-psychotics for Anti-Post Traumatic Stress Disorder Activity in Rodent Models”. CSIR;  Dec’2009-12 (Role:PI).
  4. “Experimental and clinical basis of novel treatment strategy using mitochondrial modulators in neonatal anoxic injury”. DBT;  March’2012-16 (Role:PI).
  5. “Design, Synthesis and in vitro Anticancer Evaluation of Some Novel Curcumin Analogs; Industry;  (Role:PI).2012-13
  6. “Chemical and pharmacological characterization of Shatavarin IV from Asparagus racemosus and its semi-synthetic analogues for antidepressant activity”; Sprouting grant-IIT(BHU);  Dec-2013-2014.(Role:PI)
  7. “Pharmacological evaluation of sertraline in alcohol preferring post-traumatic stress disorder rats”: Faculty-grant-IIT (BHU);  Jan-2016-2017 (PI)
  8. “Experimental Evaluation of Geroprotective Activity of Some Compounds”; Industry; 2016-2019 (Role:PI)
  9. “Evaluation of some compounds in experimental Alzheimer’s Disease” Industry; 2016-2019 (Role:PI)
  10. Pharmacological effect of novel formulation in experimental allergic encephalomyelitis rodent model; Industry; 2018-2022 (Role:PI).
  11. Pharmacology of Natural Drugs in Obesity and Eating Disorders” sponsored by Industry; 2018-2022 (Role:PI).
  12. Development of novel near infrared fluorescence imaging probes for detecting amyloid beta species in eyes of Alzheimer’s disease animal model Extramural ICMR  2019-2022, Role: Co-PI.
  13. Pharmacological evaluation of anti-diabetic effects of some natural drugs sponsored by Industry;(Role:PI).2019-2022
  14. Design, Synthesis and Biological Evaluation of O- and C-Derivatives of Phenylethanoid Glycosides as a Multi-targeting Neuroprotective Disease Modifying Agents for Alzheimer's Disease. SERB-DST, 2019-2022)".  Role: Co-PI.
  15. Design, synthesis, and biological evaluation of mechanism-based novel theranostic agents for Alzheimer’s disease. SERB-DST   Role: Co-PI.
  16. Development of enzyme enhancement treatment for neuronopathic Gaucher disease. Extramural ICMR  2023-2026, Cost Rs. Role: PI.
  17. Pharmacological exploration and repurposing of an anti-malarial drug for the treatment of triple-negative breast cancer using bovine milk exosomes as a delivery vehicle. Extramural ICMR  2023-2026,  Role: Co-PI.
  18. Development of regenerative nanofibrous bioactive conduit for treatment of spinal cord injury. ICMR  2023-2026,. Role: PI.

D

Patents Granted

  1. 2,6 -Disubstitued Piperidines and Piperazine Compounds”. By Peter A. Crooks, Linda P. Dwoskin , Guangrong Zheng, Dennis K. Miller, Seth D. Norholm, Sairam Krishnamurthy and Marlon D. Jones, U.S. Patent No.US2004/266824, December 30th, 2004
  2. Formulation of silver containing bioactive glass” by Sairam Krishnamurthy, Pankaj Paliwal Indian Patent filed on 11th May 2018. Application No.  201811017805. Patent No. 394916.GRANTED. 19th April 2022
  3. “A bioactive glass drug formulation for bone repair and regeneration and a method of preparation thereof” by Sairam Krishnamurthy and Pankaj Paliwal; Indian Patent filed on October 25, 2018, under Application No. 201811040152. Patent No. 416075. GRANTED on 30th Dec 2022
  4. Material for faster bone healing by Pralay Maiti, Arun Kumar Mahanta, Sairam Krishnamurthy and Pankaj Paliwal; Indian Patent filed on April 02, 2019, under Application No. 201911013103 no. 424726 dt. 10-.3.23
  5. A novel formulation of dabigatran solid dispersion formulation and a method of preparation thereof . Sairam Krishnamurthy and Pankaj Paliwal; Application no.: 201811029316 , 3 Aug 2018, Patent no.: 433205 dt. 30-5-2023
  6. “A novel barium bioactive glass (BaBG) formulation and a method thereof” by Sairam Krishnamurthy, Pankaj Paliwal and Smriti Gupta Indian Patent filed on September 10, 2018, under Application No. 201811033966. Patent no. 442094.dt, 1-8-23
  7. “An oral bioactive glass formulation containing aqueous micronized barium oxide for treating gastro-duodenal ulcers” Sairam Krishnamurthy and Pankaj Paliwal Indian Patent filed on September 8, 2017, Application No. 201711031854. Patent No. 443707 dt 8-8-23
  8. “A Bioactive Glass Based Formulation for Treating Cerebral Ischemic Reperfusion Injury And Method Thereof” by Sairam Krishnamurthy and Pankaj Paliwal. Indian Patent filed on September 11, 2017, Application No. 201711032099. Patent no. 478737. Dated 7-12-23.
  9. “A Bioactive Glass Scaffold and A Method of Preparation Thereof” by Sairam Krishnamurthy, Pankaj Paliwal, Shreyasi Majumdar and Sampath Kumar Arepalli. Indian Patent filed on 6th oct2017. Application No. 201711035474

Patent Applications:

  1. “An Oral Composition Of Indole-3-Carbinol and A Method Of Preparation Thereof” by Sairam Krishnamurthy , Pankaj Paliwal and Gaurav Chauhan. Indian Patent filed on July 28, 2017, Application No. 201711026941.
  2. A novel anti‐coagulant formulation and a method of preparation thereof by Sairam Krishnamurthy Pankaj Paliwal, Gyan Prakash Modi, Gopichand Gutti, and Sushil K Singh; Indian Patent filed on March 27, 2019, under Application No. 201911012094.
  3. “Rebamipide Loaded Transdermal Patch For Neurodegenerative Disease” by Sairam Krishnamurthy and Akansha Mishra Indian Patent filed on September 30, 2019, under Application No. 201911039568.
  4. Cocrystals of dimethylfumarate with enhanced physio-chemical stability and biological activity” by Sairam Krishnamurthy and Qadir Alam. Indian Patent filed on September 28, 2022, under Application No. 202211055785.

“

 

 

 

 

EDUCATION
1992-1994         M.Pharm., TN MGR Medical University, India
1999-2001         Ph.D. in Pharmacology, Banaras Hindu University, India

PROFESSIONAL APPOINTMENT

1990-1992        Asst. Manufacturing Chemist, Ranka Pharmaceuticals (P) Ltd., India

1994-1998 Asst.Prof, Department of Pharmacology, SRM University, College of Pharmacy,    India

2002- 2005      Postdoctoral Scholar, College of Pharmacy, University of Kentucky, Lexington, KY. U.S.A.

2005           Postdoctoral Fellow, Spinal cord and Brain Injury Research Center (SCoBIRC), University of Kentucky, Chandler Medical Center, Lexington, KY. U.S.A.

2005- 2006   Scientist-I, Spinal cord and Brain Injury Research Center (SCoBIRC), University of   Kentucky, Chandler Medical Center, Lexington, KY. U.S.A.

2006-2009        Reader in Pharmacology, Department of Pharmaceutics, Institute of Technology, Banaras Hindu University, Varanasi-221005, India.

2009-2018       Associate Professor, Department of Pharmaceutics, Indian Institute of Technology, (Banaras Hindu University), Varanasi-221005, India.

2018-Present     Professor, Department of Pharmaceutical engineering and Technology, Indian Institute of Technology, (Banaras Hindu University), Varanasi-221005, India.