ashish.phe's picture
Dr. Ashish Kumar Agrawal
Assistant Professor
Department of Pharmaceutical Engineering and Technology
ashish.phe@iitbhu.ac.in
+91 6376983676
Area of Interest: 
Pharmaceutical Nanotechnology and drug delivery

EDUCATION/TRAINING UNIVERSITY YEAR
Post-Doctoral Fellow University of Louisville, Kentucky, USA 2015-18
Ph.D. National Institute of Pharmaceutical Education and Research (NIPER), SAS Nagar (Punjab) 2010-14
M. Pharm.* (Pharmaceutics) Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal (M.P) 2007-09
B. Pharm. Rajasthan University of Health and Sciences, Jaipur (Raj.) 2003-07
* Institute Gold Medal
  • Targeted and controlled drug delivery by using nanotechnology based approaches.
  • Development of vesicular and particulate nanocarriers for various biomedical applications.
  • Protein and peptide delivery through alternative routes.
  • Exosomes for drug delivery and diagnosis.
  1. Sankha Bhattacharya, Krishna Kumar Patel, Deepa Dehari, Ashish Kumar Agrawal Sanjay Singh, Melatonin and its ubiquitous anticancer effects. Molecular and Cellular Biochemistry (https://doi.org/10.1007/s11010-019-03617-5) (I.F. 2.884)
  2. Krishna Kumar Patel, Ashish Kumar Agrawal, Md. Meraj Anjum, Muktanand Tripathi, Nidhi Pandey, Sankha Bhattacharya, Ragini Tilak, Sanjay Singh, DNase‑I functionalization of ciprofloxacin‑loaded chitosan nanoparticles overcomes the biofilm‑mediated resistance of Pseudomonas aeruginosa. Applied Nanoscience, (https://doi.org/10.1007/s13204-019-01129-8) (I.F. 2.951)
  3. Krishna Kumar Patel, D. Bhavya Surekha, Muktanand Tripathi, Md. Meraj Anjum, M. S. Muthu, Ragini Tilak, Ashish Kumar Agrawal, Sanjay Singh, Antibiofilm Potential of Silver Sulfadiazine-Loaded Nanoparticle Formulations: A Study on the Effect of DNase-I on Microbial Biofilm and Wound Healing Activity. Molecular Pharmaceutics, (https://doi.org/10.1021/acs.molpharmaceut.9b00527) (I.F. 4.556)
  4. Shilpkala Gade, Krishna Kumar Patel, Chandan Gupta, Meraj Anjum, Deepika Deepika, Ashish Kumar Agrawal, Sanjay Singh, An ex vivo Evaluation of Moxifloxacin Nanostructured Lipid Carrier enriched in situ gel for Transcorneal permeation on Goat Cornea. Journal of Pharmaceutical Sciences, (https://doi.org/10.1016/j.xphs.2019.04.005) (I.F. 3.075)
  5. Krishna Kumar Patel, Muktanand Tripathi, Nidhi Pandey, Ashish Kumar Agrawal, Shilpkala Gade, Md. Meraj Anjum, Ragini Tilak, Sanjay Singh⁠, Alginate lyase immobilized chitosan nanoparticles of ciprofloxacin for the improved antimicrobial activity against the biofilm associated mucoid P. aeruginosa infection in cystic fibrosis. International Journal of Pharmaceutics, 563, 2019:30-42. (I.F. 3.862)
  6. Krishna Kumar Patel, Shilpkala Gade, Md. Meraj Anjum, Sanjay Kumar Singh, Pralay Maiti, Ashish Kumar Agrawal, Sanjay Singh, Effect of penetration enhancers and amorphization on transdermal permeation flux of Raloxifene encapsulated solid lipid nanoparticles: an ex vivo study on human skin. Applied Nanoscience, (https://doi.org/10.1007/s13204-019-01004-6) (I.F.-2.951).
  7. Farrukh Aqil, Radha Munagala, Jeyaprakash Jeyabalan, Ashish Kumar Agrawal, Al-Hassan Kyakulaga, Sarah A. Wilcher Ramesh C. Gupta, Milk exosomes - Natural nanoparticles for siRNA delivery. Cancer Letters, 449, 2019:186-195. (I.F.-6.491)
  8. Dileep Urimi, Ashish Kumar Agrawal, Varun Kushwah, Sanyog Jain, Polyglutamic acid functionalization of chitosan nanoparticles enhances the therapeutic efficacy of insulin following oral administration. AAPS PharmSciTech, 20, 2019:131. (I.F.-2.451)
  9. Varun Kushwah, Devesh Kumar, Ashish Kumar Agrawal, Sanyog Jain, Improved antitumor efficacy and reduced toxicity of docetaxel using anacardic acid functionalized stealth liposomes. Colloids and Surfaces B: Biointerfaces, 172, 2018:213-223. (I.F.-3.997)
  10. Varun Kushwah, Sameer S. Katiyar, Ashish Kumar Agrawal, Isha Saraf, Inder Pal Singh, Dimitrios A. Lamprou, Ramesh C. Gupta, Sanyog Jain, Implication of linker length on cell cytotoxicity, pharmacokinetic and toxicity profile of gemcitabine-docetaxel combinatorial dual drug conjugate. International Journal of Pharmaceutics, 548(1), 2018:357-374. (I.F.-3.862)
  11. Varun Kushwah, Sameer S. Katiyar, Chander Parkash Dora, Ashish Kumar Agrawal, Dimitrios A. Lamprou, Ramesh C. Gupta, Sanyog Jain, Co-delivery of docetaxel and gemcitabine by anacardic acid modified self-assembled albumin nanoparticles for effective breast cancer management. Acta Biomaterialia, 73, 2018:424-436. (I.F.-6.383)
  12. Varun Kushwah, Sameer S. Katiyar, Ashish Kumar Agrawal, Ramesh C. Gupta, Sanyog Jain, Co-delivery of docetaxel and gemcitabine using PEGylated self-assembled stealth nanoparticles for improved breast cancer therapy. Nanomedicine: Nanotechnology, Biology and Medicine, 14, 2018:1629-1641. (I.F. 6.5)
  13. Swapnil Singh, Varun Kushwah, Ashish Kumar Agrawal, Sanyog Jain, Co-encapsulation of insulin and quercetin in liquid crystalline nanoparticles: Implications on oral bioavailability, antidiabetic and antioxidant efficacy. Nanomedicine, 13(5), 2018:521-537. (I.F-5.005)
  14. Varun Kushwah, Ashish Kumar Agrawal, Chander Parkash Dora, David Mallinson, Dimitrios A. Lamprou, Ramesh C. Gupta, Sanyog Jain, Novel Gemcitabine Conjugated Albumin Nanoparticles: a Potential Strategy to Enhance Drug Efficacy in Pancreatic Cancer Treatment. Pharmaceutical Research, 34(11), 2017:2295-2311. (I.F.-3.335)
  15. Farrukh Aqil1, Jeyaprakash Jeyabalan, Ashish K. Agrawal, Al-Hassan Kyakulaga, Radha Munagala, Lynn Parker, Ramesh C. Gupta, Exosomal delivery of anthocyanidins for the management of ovarian cancer. Food & Function, 8, 2017:4100-4107. (I.F-3.289)
  16. Farrukh Aqil1, Radha Munagala, Jeyaprakash Jeyabalan, Ashish K. Agrawal, Ramesh C. Gupta, Exosomes for the enhanced tissue bioavailability and efficacy of curcumin. AAPS Journal, 19(6), 2017:1691-1702. (I.F.-3.804)
  17. Ashish K. Agrawal, Kuldeep Kumar, Varun Kushwah, Sanyog Jain, “Liquid Crystalline Nanoparticles”: Rationally designed vehicle to improve stability and therapeutic efficacy of insulin following oral administration. Molecular Pharmaceutics, 14(6), 2017:1874-1882. (I.F.-4.556)
  18. Deepanshu Shilpi, Varun Kushwah, Ashish K. Agrawal, Sanyog Jain, Improved Stability and Enhanced Oral Bioavailability of Atorvastatin Loaded Stearic Acid Modified Gelatin Nanoparticles. Pharmaceutical Research, 34(7), 2017:1505-1516. (I.F.-3.335)
  19. Ashish K. Agrawal, Farrukh Aqil, Jeyaprakash Jeyabalan, Wendy A. Spencer, Joshua Beck, Beth W. Gachuki, Sara S. Alhakeem, Karine Oben, Radha Munagala, Subbarao Bondada, Ramesh C. Gupta, Milk-derived exosomes for oral delivery of paclitaxel. Nanomedicine: Nanotechnology, Biology and Medicine, 13(5), 2017:1627-1636. (I.F. 6.5)
  20. Sanyog Jain, Tanya Garg, Varun Kushwah, Kaushik Thanki, Ashish K. Agrawal, α-Tocopherol as functional excipient for Resveratrol and Coenzyme Q10 loaded SNEDDS for improved bioavailability and prophylaxis of breast cancer. Journal of Drug Targeting, 25(6), 2017:554-565. (I.F. 3.408)
  21. Radha Munagala, Farrukh Aqil1, Jeyaprakash Jeyabalan, Ashish K. Agrawal, Ashley M Mudd, Al-Hassan Kyakulaga, Manicka V Vadhanam, Ramesh C. Gupta, Exosomal formulation of anthocyanidins against multiple cancer types. Cancer Letters, 393, 2017:94-102. (I.F.- 6.491)
  22. Farrukh Aqil, Hina Kausar, Ashish K. Agrawal, Jeyaprakash Jeyabalan, Al-Hassan Kyakulaga, Radha Munagala, Ramesh Gupta, Exosomal formulation enhances therapeutic response of celastrol against lung cancer. Experimental and Molecular Pathology, 101 (1), 2016:12-21. (I.F.-2.566)
  23. Ashish K. Agrawal, Dileep Urimi, Harshad Harde, Varun Kushwah, Sanyog Jain, Folate appended chitosan nanoparticles augment the stability, bioavailability and efficacy of insulin in diabetic rats following oral administration. RSC Advances, 5 (127), 2015:105179-105193. (I.F.-2.936)
  24. Sanyog Jain, Gollapalli Spandana, Ashish K. Agrawal, Varun Kushwah, Kaushik Thanki, Enhanced antitumor efficacy and reduced toxicity of docetaxel loaded estradiol functionalized stealth polymeric nanoparticles. Molecular Pharmaceutics, 12 (11), 2015:3871-3884. (I.F.-4.556)
  25. Harshad Harde, Ashish K. Agrawal, Sanyog Jain, Tetanus toxoids loaded layer-by-layer nanoassemblies as vaccine adjuvant with improved oral stability and immunostimulatory response. Drug Delivery and Translational Research, 5 (5), 2015:498-510. (I.F.-3.395)
  26. Harshad Harde, Ashish K. Agrawal, Mahesh Katariya, Dnyaneshwar Kale, Sanyog Jain, Development of Topical Adapalene-Solid Lipid Nanoparticles Loaded Gel with Enhanced Efficacy and Improved Skin Tolerability. RSC Advances, 5(55), 2015:43917-43929. (I.F.-2.936)
  27. Sanyog Jain, Sandeep Kumar, Ashish K. Agrawal, Kaushik Thanki, Uttam C. Banerjee, Hyaluronic acid-PEI-Cyclodextrin polyplexes: Implications on in vitro and in vivo transfection efficiency and toxicity. RSC Advances, 5(51), 2015:41144-41154. (I.F.-2.936)
  28. Harshad Harde, Krupa Siddhapura, Ashish K. Agrawal, Sanyog Jain, Divalent toxoids loaded stable chitosan-glucomannan nanoassemblies for efficient systemic, mucosal and cellular immunostimulatory response following oral administration. International Journal of Pharmaceutics, 487 (1-2), 2015:292-304 (I.F.-3.862)
  29. Harshad Harde, Ashish K. Agrawal, Sanyog Jain, Trilateral ‘3P’ mechanics of stabilized layersomes technology for efficient oral immunization. Journal of Biomedical Nanotechnology, 11 (3), 2015:363-381. (I.F.-5.068)
  30. Vineet Kumar Rai, Nidhi Mishra, Ashish K. Agrawal, Sanyog Jain, Narayan Prasad Yadav, Novel drug delivery system: an immense hope for diabetics. Drug Delivery, 23(7), 2016:2371-2390. (I.F.-3.095)
  31. Harshad Harde, Krupa Siddhapura, Ashish K. Agrawal, Sanyog Jain, Development of Dual Toxoids Loaded Layersomes for Competent Immunostimulatory Response Following Peroral Administration. Nanomedicine (London), 10(7), 2014:1077-1091. (I.F.-5.005)
  32. Abhishek Kaler, Amit Kumar Mittal, Mahesh Katariya, Harshad Harde, Ashish K. Agrawal, Sanyog Jain, Uttam Chand Banerjee, An investigation of in vivo wound healing activity of biologically synthesized silver nanoparticles. Journal of Nanoparticle Research, 16 (9), 2014:1-10. (I.F.-2.127)
  33. Sanyog Jain, Roopal Jain, Manasmita Das, Ashish K. Agrawal, Kaushik Thanki, Varun Kushwaha, Combinatorial bio-conjugation of gemcitabine and curcumin enables dual drug delivery with synergistic anticancer efficacy and reduced toxicity. RSC Advances, 4 (55), 2014:29193-29201. (I.F.-2.936)
  34. Harshad Harde, Ashish K. Agrawal, Sanyog Jain, Tetanus Toxoids Loaded Glucomannosylated Chitosan Based Nanohoming Vaccine Adjuvant With Improved Oral Stability And Immunostimulatory Response. Pharmaceutical Research, 32 (1), 2014:122-134. (I.F.-3.335)
  35. Harshad Harde, Ashish K. Agrawal, Sanyog Jain, Development of stabilized glucomannosylated chitosan nanoparticles using tandem crosslinking method for oral vaccine delivery. Nanomedicine (London), 9 (16), 2014:2511-2529. (I.F.-5.005)
  36. Manasmita Das, Roopal Jain, Ashish K. Agrawal, Kaushik Thanki, Sanyog Jain, Macromolecular bipill of gemcitabine and methotrexate facilitates tumor-specific dual drug therapy with higher benefit-to-risk ratio. Bioconjugate Chemistry, 25 (3), 2014:501-509. (I.F.-4.485)
  37. Ashish K. Agrawal, Harshad Harde, Kaushik Thanki, Sanyog Jain, Improved stability and antidiabetic potential of insulin containing folic acid functionalized polymer stabilized multilayered liposomes following oral administration. Biomacromolecules, 15 (1), 2013:350-360. (I.F.-5.738) (Article met attention of global media and it became front page news in almost all leading newspapers during 18-21 December 2013)
  38. Sanyog Jain, Harshad Harde, Anura Indulkar, Ashish K. Agrawal, Improved stability and immunological potential of tetanus toxoid containing surface engineered bilosomes following oral administration. Nanomedicine: Nanotechnology, Biology and Medicine, 10(2), 2013:431-440. (I.F.-6.5)
  39. Sanyog Jain, Anura Indulkar, Harshad Harde, Ashish K. Agrawal Oral mucosal immunization using mannosylated bilosome. Journal of Biomedical Nanotechnology, 10(6), 2014:932-947. (I.F.-5.068)
  40. Sanyog Jain, Sandeep Kumar, Ashish K. Agrawal, Kaushik Thanki, Uttam C. Banerjee, Enhanced transfection efficiency and reduced cytotoxicity of novel lipid-polymer hybrid nanoplexes. Molecular Pharmaceutics, 10(6), 2013:2416-2425. (I.F.-4.556)
  41. Sanyog Jain, Jagadish M. Sharma, Ashish K. Agrawal, Rahul R. Mahajan, Surface stabilized efavirenz nanoparticles for oral bioavailability enhancement. Journal of Biomedical Nanotechnology, 9, 2013:1862-1874. (I.F.-5.068)
  42. Harshad Harde, Raman Preet Singh, Ashish K. Agrawal, Sanyog Jain, Disease-based selection of nanocarriers indrug delivery based on hydrophobicity and surface charge, Journal of Nanogenomics and Nanomedicine 2013 (doi:10.9777/ngnm.2013.10001).
  43. Sanyog Jain, Swapnil R. Patil, Nitin K. Swarnakar, Ashish K. Agrawal, Oral delivery of doxorubicin using novel polyelectrolytes stabilized liposomes (layersomes), Molecular Pharmaceutics, 9(9), 2012: 2626-2635. (I.F.-4.556)
  44. Ashish K. Agrawal, Manasmita Das, Sanyog Jain, In-situ gel system as "smart" carriers for sustained ocular drug delivery. Expert Opinion on Drug Delivery, 9(4), 2012:383-402. (I.F.-5.553)
  45. Ashish K. Agrawal, Prem N. Gupta, Amit Khanna, Ratnesh K. Sharma, Harish K. Chandrabanshi, Neha Gupta, Umesh K. Patil, Sahadev K. Yadav, Development and characterization of in situ gel system for nasal insulin delivery. Die Pharmazie, 65, 2010:188-193. (I.F.-1.016)
  46. Harshit Choudhary, Ashish K. Agrawal, Ravi Malviya, Sahadev K. Yadav, Yusuf A. Jaliwala, Umesh K. Patil, Evaluation and optimization of preparative variables for controlled-release floating microspheres of levodopa/carbidopa. Die Pharmazie, 65, 2010:194-198. (I.F.-1.016)
  • “AAPS Post-Doctoral Fellow Award, 2017” honored by American Association of Pharmaceutical Scientists at annual AAPS conference held at San Diego Convention Center, San Diego, USA from 12-15 November, 2017.
  • Best Poster Award at annual meeting of International Society for Extracellular Vesicles held at Toronto, Canada from 18-21 May 2017.
  • “Gandhian Young Technological Innovation Awards, 2017” at the Festival of Innovations (FOIN), March 4-11, 2017 hosted by The office of the President of India, Rashtrapati Bhavan, New Delhi.
  • “Punjab Young Scientist Award – 2013” honored by Punjab Academy of Science at 17th Punjab Science Congress, held at Punjab Technical University, Jalandhar, 14-16 Feb, 2014. 
  • Selected among the best 20 teams all over India for the workshop 5th BEST INDIA-2013 organized by ABLE (Association of Biotechnology Led Enterprises) in association with DST at Bangalore, from 9-13th October, 2013.
  • “Rising Sun in Asia” award in 40th Annual Meeting & Exposition of the Controlled Release Society at Hawaii Convention Centre, Honolulu, Hawaii, USA, from 21-24th July, 2013.
  • DBT International Travel Award for attending and presenting poster at 40th Annual Meeting and Exposition of the Controlled Release Society, Hawaii Convention Center, Honolulu, Hawaii, USA, from 21-24th July, 2013.
  • CSIR International Travel Grant for attending and presenting poster at 40th Annual Meeting and Exposition of the Controlled Release Society, Hawaii Convention Center, Honolulu, Hawaii, USA, from 21-24th July, 2013.
  • Senior Research Fellowship awarded by Council of Scientific and Industrial Research, New Delhi, Govt. of India (2013).