ashish.phe's picture
Dr. Ashish Kumar Agrawal
Assistant Professor
Department of Pharmaceutical Engineering and Technology
ashish.phe@iitbhu.ac.in
+91 6376983676
Area of Interest: 
Pharmaceutical Nanotechnology and drug delivery

EDUCATION/TRAINING UNIVERSITY YEAR
Post-Doctoral Fellow University of Louisville, Kentucky, USA 2014-18
Ph.D. National Institute of Pharmaceutical Education and Research (NIPER), SAS Nagar (Punjab) 2010-14
M. Pharm.* (Pharmaceutics) Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal (M.P) 2007-09
B. Pharm. Rajasthan University of Health and Sciences, Jaipur (Raj.) 2003-07
* Institute Gold Medal
  • Targeted and controlled drug delivery by using nanotechnology based approaches.
  • Development of vesicular and particulate nanocarriers for various biomedical applications.
  • Protein and peptide delivery through alternative routes.
  • Exosomes for drug delivery and diagnosis.
  1. Varun Kushwah, Sameer S. Katiyar, Chander Parkash Dora, Ashish Kumar Agrawal, Dimitrios A. Lamprou, Ramesh C. Gupta, Sanyog Jain, Co-delivery of docetaxel and gemcitabine by anacardic acid modified self-assembled albumin nanoparticles for effective breast cancer management. Acta Biomaterialia. (DOI: https://doi.org/10.1016/j.actbio.2018.03.057) (I.F.-6.319)
  2. Varun Kushwah, Sameer S. Katiyar, Ashish Kumar Agrawal, Ramesh C. Gupta, Sanyog Jain, Co-delivery of docetaxel and gemcitabine using PEGylated self-assembled stealth nanoparticles for improved breast cancer therapy. Nanomedicine: Nanotechnology, Biology and Medicine, 14, 2018:1629-1641. (I.F. 5.72)
  3. Swapnil Singh, Varun Kushwah, Ashish Kumar Agrawal, Sanyog Jain, Co-encapsulation of insulin and quercetin in liquid crystalline nanoparticles: Implications on oral bioavailability, antidiabetic and antioxidant efficacy. Nanomedicine, 13(5), 2018:521-537. (I.F-4.727)
  4. Varun Kushwah, Ashish Kumar Agrawal, Chander Parkash Dora, David Mallinson, Dimitrios A. Lamprou, Ramesh C. Gupta, Sanyog Jain, Novel Gemcitabine Conjugated Albumin Nanoparticles: a Potential Strategy to Enhance Drug Efficacy in Pancreatic Cancer Treatment. Pharmaceutical Research, 34(11), 2017:2295-2311. (I.F.-3.002)
  5. Farrukh Aqil1, Jeyaprakash Jeyabalan, Ashish K. Agrawal, Al-Hassan Kyakulaga, Radha Munagala, Lynn Parker, Ramesh C. Gupta, Exosomal delivery of anthocyanidins for the management of ovarian cancer. Food & Function, 8, 2017:4100-4107. (I.F-3.247)
  6. Farrukh Aqil1, Radha Munagala, Jeyaprakash Jeyabalan, Ashish K. Agrawal, Ramesh C. Gupta, Exosomes for the enhanced tissue bioavailability and efficacy of curcumin. AAPS Journal, 19(6), 2017:1691-1702. (I.F.-3.423)
  7. Ashish K. Agrawal, Kuldeep Kumar, Varun Kushwah, Sanyog Jain, “Liquid Crystalline Nanoparticles”: Rationally designed vehicle to improve stability and therapeutic efficacy of insulin following oral administration. Molecular Pharmaceutics, 14(6), 2017:1874-1882. (I.F.-4.44)
  8. Deepanshu Shilpi, Varun Kushwah, Ashish K. Agrawal, Sanyog Jain, Improved Stability and Enhanced Oral Bioavailability of Atorvastatin Loaded Stearic Acid Modified Gelatin Nanoparticles. Pharmaceutical Research, 34(7), 2017:1505-1516. (I.F.-3.002)
  9. Ashish K. Agrawal, Farrukh Aqil, Jeyaprakash Jeyabalan, Wendy A. Spencer, Joshua Beck, Beth W. Gachuki, Sara S. Alhakeem, Karine Oben, Radha Munagala, Subbarao Bondada, Ramesh C. Gupta, Milk-derived exosomes for oral delivery of paclitaxel. Nanomedicine: Nanotechnology, Biology and Medicine, 13(5), 2017:1627-1636. (I.F. 5.72)
  10. Sanyog Jain, Tanya Garg, Varun Kushwah, Kaushik Thanki, Ashish K. Agrawal, α-Tocopherol as functional excipient for Resveratrol and Coenzyme Q10 loaded SNEDDS for improved bioavailability and prophylaxis of breast cancer. Journal of Drug Targeting, 25(6), 2017:554-565. (I.F. 3.068)
  11. Radha Munagala, Farrukh Aqil1, Jeyaprakash Jeyabalan, Ashish K. Agrawal, Ashley M Mudd, Al-Hassan Kyakulaga, Manicka V Vadhanam, Ramesh C. Gupta, Exosomal formulation of anthocyanidins against multiple cancer types. Cancer Letters, 393, 2017:94-102. (I.F.- 6.375)
  12. Farrukh Aqil, Hina Kausar, Ashish K. Agrawal, Jeyaprakash Jeyabalan, Al-Hassan Kyakulaga, Radha Munagala, Ramesh Gupta, Exosomal formulation enhances therapeutic response of celastrol against lung cancer. Experimental and Molecular Pathology, 101 (1), 2016:12-21. (I.F.-2.423)
  13. Ashish K. Agrawal, Dileep Urimi, Harshad Harde, Varun Kushwah, Sanyog Jain, Folate appended chitosan nanoparticles augment the stability, bioavailability and efficacy of insulin in diabetic rats following oral administration. RSC Advances, 5 (127), 2015:105179-105193. (I.F.-3.108)
  14. Sanyog Jain, Gollapalli Spandana, Ashish K. Agrawal, Varun Kushwah, Kaushik Thanki, Enhanced antitumor efficacy and reduced toxicity of docetaxel loaded estradiol functionalized stealth polymeric nanoparticles. Molecular Pharmaceutics, 12 (11), 2015:3871-3884. (I.F.-4.44)
  15. Harshad Harde, Ashish K. Agrawal, Sanyog Jain, Tetanus toxoids loaded layer-by-layer nanoassemblies as vaccine adjuvant with improved oral stability and immunostimulatory response. Drug Delivery and Translational Research, 5 (5), 2015:498-510.
  16. Harshad Harde, Ashish K. Agrawal, Mahesh Katariya, Dnyaneshwar Kale, Sanyog Jain, Development of Topical Adapalene-Solid Lipid Nanoparticles Loaded Gel with Enhanced Efficacy and Improved Skin Tolerability. RSC Advances, 5(55), 2015:43917-43929. (I.F.-3.108)
  17. Sanyog Jain, Sandeep Kumar, Ashish K. Agrawal, Kaushik Thanki, Uttam C. Banerjee, Hyaluronic acid-PEI-Cyclodextrin polyplexes: Implications on in vitro and in vivo transfection efficiency and toxicity. RSC Advances, 5(51), 2015:41144-41154. (I.F.-3.108)
  18. Harshad Harde, Krupa Siddhapura, Ashish K. Agrawal, Sanyog Jain, Divalent toxoids loaded stable chitosan-glucomannan nanoassemblies for efficient systemic, mucosal and cellular immunostimulatory response following oral administration. International Journal of Pharmaceutics, 487 (1-2), 2015:292-304 (I.F.-3.649)
  19. Harshad Harde, Ashish K. Agrawal, Sanyog Jain, Trilateral ‘3P’ mechanics of stabilized layersomes technology for efficient oral immunization. Journal of Biomedical Nanotechnology, 11 (3), 2015:363-381. (I.F.-4.521)
  20. Vineet Kumar Rai, Nidhi Mishra, Ashish K. Agrawal, Sanyog Jain, Narayan Prasad Yadav, Novel drug delivery system: an immense hope for diabetics. Drug Delivery, 23(7), 2016:2371-2390. (I.F.-6.402)
  21. Harshad Harde, Krupa Siddhapura, Ashish K. Agrawal, Sanyog Jain, Development of Dual Toxoids Loaded Layersomes for Competent Immunostimulatory Response Following Peroral Administration. Nanomedicine (London), 10(7), 2014:1077-1091. (I.F.-4.727)
  22. Abhishek Kaler, Amit Kumar Mittal, Mahesh Katariya, Harshad Harde, Ashish K. Agrawal, Sanyog Jain, Uttam Chand Banerjee, An investigation of in vivo wound healing activity of biologically synthesized silver nanoparticles. Journal of Nanoparticle Research, 16 (9), 2014:1-10. (I.F.-2.02)
  23. Sanyog Jain, Roopal Jain, Manasmita Das, Ashish K. Agrawal, Kaushik Thanki, Varun Kushwaha, Combinatorial bio-conjugation of gemcitabine and curcumin enables dual drug delivery with synergistic anticancer efficacy and reduced toxicity. RSC Advances, 4 (55), 2014:29193-29201. (I.F.-3.108)
  24. Harshad Harde, Ashish K. Agrawal, Sanyog Jain, Tetanus Toxoids Loaded Glucomannosylated Chitosan Based Nanohoming Vaccine Adjuvant With Improved Oral Stability And Immunostimulatory Response. Pharmaceutical Research, 32 (1), 2014:122-134. (I.F.-3.002)
  25. Harshad Harde, Ashish K. Agrawal, Sanyog Jain, Development of stabilized glucomannosylated chitosan nanoparticles using tandem crosslinking method for oral vaccine delivery. Nanomedicine (London), 9 (16), 2014:2511-2529. (I.F.-4.727)
  26. Manasmita Das, Roopal Jain, Ashish K. Agrawal, Kaushik Thanki, Sanyog Jain, Macromolecular bipill of gemcitabine and methotrexate facilitates tumor-specific dual drug therapy with higher benefit-to-risk ratio. Bioconjugate Chemistry, 25 (3), 2014:501-509. (I.F.-4.818)
  27. Ashish K. Agrawal, Harshad Harde, Kaushik Thanki, Sanyog Jain, Improved stability and antidiabetic potential of insulin containing folic acid functionalized polymer stabilized multilayered liposomes following oral administration. Biomacromolecules, 15 (1), 2013:350-360. (I.F.-5.246) (Article met attention of global media and it became front page news in almost all leading newspapers during 18-21 December 2013)
  28. Sanyog Jain, Harshad Harde, Anura Indulkar, Ashish K. Agrawal, Improved stability and immunological potential of tetanus toxoid containing surface engineered bilosomes following oral administration. Nanomedicine: Nanotechnology, Biology and Medicine, 10(2), 2013:431-440. (I.F.-5.72)
  29. Sanyog Jain, Anura Indulkar, Harshad Harde, Ashish K. Agrawal Oral mucosal immunization using mannosylated bilosome. Journal of Biomedical Nanotechnology, 10(6), 2014:932-947. (I.F.-4.521)
  30. Sanyog Jain, Sandeep Kumar, Ashish K. Agrawal, Kaushik Thanki, Uttam C. Banerjee, Enhanced transfection efficiency and reduced cytotoxicity of novel lipid-polymer hybrid nanoplexes. Molecular Pharmaceutics, 10(6), 2013:2416-2425. (I.F.-4.44)
  31. Sanyog Jain, Jagadish M. Sharma, Ashish K. Agrawal, Rahul R. Mahajan, Surface stabilized efavirenz nanoparticles for oral bioavailability enhancement. Journal of Biomedical Nanotechnology, 9, 2013:1862-1874. (I.F.-4.521)
  32. Harshad Harde, Raman Preet Singh, Ashish K. Agrawal, Sanyog Jain, Disease-based selection of nanocarriers indrug delivery based on hydrophobicity and surface charge, Journal of Nanogenomics and Nanomedicine 2013 (doi:10.9777/ngnm.2013.10001).
  33. Sanyog Jain, Swapnil R. Patil, Nitin K. Swarnakar, Ashish K. Agrawal, Oral delivery of doxorubicin using novel polyelectrolytes stabilized liposomes (layersomes), Molecular Pharmaceutics, 9(9), 2012: 2626-2635. (I.F.-4.44)
  34. Ashish K. Agrawal, Manasmita Das, Sanyog Jain, In-situ gel system as "smart" carriers for sustained ocular drug delivery. Expert Opinion on Drug Delivery, 9(4), 2012:383-402. (I.F.-5.657)
  35. Ashish K. Agrawal, Prem N. Gupta, Amit Khanna, Ratnesh K. Sharma, Harish K. Chandrabanshi, Neha Gupta, Umesh K. Patil, Sahadev K. Yadav, Development and characterization of in situ gel system for nasal insulin delivery. Die Pharmazie, 65, 2010:188-193. (I.F.-1.126)
  36. Harshit Choudhary, Ashish K. Agrawal, Ravi Malviya, Sahadev K. Yadav, Yusuf A. Jaliwala, Umesh K. Patil, Evaluation and optimization of preparative variables for controlled-release floating microspheres of levodopa/carbidopa. Die Pharmazie, 65, 2010:194-198. (I.F.-1.126)

Book Chapters

  1. Ashish Kumar Agrawal, Dileep Urimi, Sanyog Jain, (2015) Multifunctional polymeric nano-carriers in targeted drug delivery; Targeted Drug Delivery – Concepts and Design, Springer publications, USA, 461-500. (doi: 10.1007/978-3-319-11355-5_15)
  • “AAPS Post-Doctoral Fellow Award, 2017” honored by American Association of Pharmaceutical Scientists at annual AAPS conference held at San Diego Convention Center, San Diego, USA from 12-15 November, 2017.
  • Best Poster Award at annual meeting of International Society for Extracellular Vesicles held at Toronto, Canada from 18-21 May 2017.
  • “Gandhian Young Technological Innovation Awards, 2017” at the Festival of Innovations (FOIN), March 4-11, 2017 hosted by The office of the President of India, Rashtrapati Bhavan, New Delhi.
  • “Punjab Young Scientist Award – 2013” honored by Punjab Academy of Science at 17th Punjab Science Congress, held at Punjab Technical University, Jalandhar, 14-16 Feb, 2014. 
  • Selected among the best 20 teams all over India for the workshop 5th BEST INDIA-2013 organized by ABLE (Association of Biotechnology Led Enterprises) in association with DST at Bangalore, from 9-13th October, 2013.
  • “Rising Sun in Asia” award in 40th Annual Meeting & Exposition of the Controlled Release Society at Hawaii Convention Centre, Honolulu, Hawaii, USA, from 21-24th July, 2013.
  • DBT International Travel Award for attending and presenting poster at 40th Annual Meeting and Exposition of the Controlled Release Society, Hawaii Convention Center, Honolulu, Hawaii, USA, from 21-24th July, 2013.
  • CSIR International Travel Grant for attending and presenting poster at 40th Annual Meeting and Exposition of the Controlled Release Society, Hawaii Convention Center, Honolulu, Hawaii, USA, from 21-24th July, 2013.
  • Senior Research Fellowship awarded by Council of Scientific and Industrial Research, New Delhi, Govt. of India (2013).