Bioprocess Development and Digitalization Laboratory

Our lab focuses on applying the principles of bioprocess engineering and modeling approaches to speed up industrial biomanufacturing.

• • Development of Digital twins to improve bioproduction
• • Establishment of microbial  (Yeast) process for agricultural waste valorisation by model assisted approach

List of Journal Articles

9. Sivasankari Marimuthu, S.M. Pappu and Karthikeyan Rajendran (2022) Artificial neural network modelling and statistical optimization of medium components for enhanced exopolysaccharide production by Bacillus sp. ES003, Preparative Biochemistry and Biotechnology, doi.org/10.1080/10826068.2022.2098322

8. Amit kumar, Sweta Mohan, Shatabdi Satpathy, S.M. Pappu and S. N. Gummadi (2022) Effect of exogenous additives and stress inducers on xylitol production by Debaryomyces nepalensis in batch culture, Biofuels, Bioproducts and Biorefining, doi.org/10.1002/bbb.2362.

7. S.M. Pappu and S.N. Gummadi (2018) Effect of cosubstrate on xylitol production by Debaryomyces nepalensis NCYC 3413: a cybernetic modellingapproach, Process Biochemistry, 69:12-21, doi.org/10.1- 16/j.procbio.2018.03.023.

6. S.M.Pappu andS.N.Gummadi (2017)Artificialneuralnetworkandregressioncoupledgenetic algorithm to optimize parameters for enhanced xylitol production by Debaryomyces nepalensis in bioreactor, Biochemical Engineering Journal 120: 136 – 145, doi.org/10.1016/j.bej.2017.01.010..

5. S.M. Pappu and S.N. Gummadi (2017) Second generation bioethanol production: Technical progress, possibilities and challenges. Journal of Energy and Environmental Sustainability, 4:36-44,doi.org/10.47469/JEES.2017.v04.100045.

4. S.M. Pappu and S.N. Gummadi (2016) Modelling and simulation of xylitol production in bioreactor by Debaromyces nepalensis NCYC3413 using unstructured and artificial neural network models, Bioresource Technology 220: 490 – 499, doi;10.1016/j.biortech.2016.08.097.

3. S.M. Pappu and S.N. Gummadi (2016) Multi response optimization for enhanced xylitol production by Debaryomyces nepalensis in bioreactor, 3 Biotech 6 (2): 151, doi: 10.1007/s13205- 016-0467-x

2. S.M. Pappu, T. Basak and S.N. Gummadi (2015) Mathematical modeling of macroscale phenomena: Oxygen transfer for solid state fermentation in static tray bioreactor, British Biotechnology Journal 9: 1-14.

1. S.M. Pappu, G.K. Vijayakumar, R. Viraraghavan (2013) Artificial neural network model for predicting production of Spirulina platensis in outdoor culture, Bioresource Technology 130: 224 - 230,doi.org/10.1016/j.biortech.2012.12.082.

List of Book Chapters

3.S.M. Pappu and S. N. Gummadi (2021) Prospects of utilization of various solid agrowastes for making value added products for sustainable development. In: Waste Management: Opportunities & Challenges for Sustainable Development (eds.), CRC Press, Taylor and Francis Group.

2.S.M. Pappu, S. N. Gummadi and T. Jayabalan (2022) Modeling and Optimization of microbial production of xylitol. In: Role of Microbes in. Industrial Products and Processes (eds.), 223 – 254, Scrivener Publishing LLC.

1. S. N. Mohamed, B. Thulasinathan, A. Algarsamy, S.M. Pappu, Bindhya K. Purushothaman and T. Jayabalan (2022) Role of Microorganisms in Bioelectrochemical Systems for Hydrogen and Bioelectricity Production. In: Role of Microbes in. Industrial Products and Processes (eds.), 279 – 304, Scrivener Publishing LLC.

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This page will soon be updated.