aksingh.bce's picture
Dr. Ashish Kumar Singh
Assistant Professor
School of Biochemical Engineering IIT BHU
aksingh.bce@iitbhu.ac.in
+91-7376676870
Area of Interest: 
Bacterial genetics, gene expression, small bio-molecules and metagenomics.

Dr. Ashish Kumar Singh is an Assistant Professor at School of Biochemical Engineering, IIT (BHU), Varanasi. He did his M.Sc. (2001) from Department of Biochemistry, Institute of Science, Banaras Hindu University (BHU). He has done his Ph.D. (2009) from CSIR-Centre for Cellular and Molecular Biology (CCMB), Hyderabad. He was a Post Doctoral Fellow (June 2008 to May 2013) at University of Maryland School of Medicine (Baltimore, USA), National Institutes of Health (NIH/NCI, Frederick, USA) and Trudeau Institute (Saranac Lake, New York, USA). Before joining IIT (BHU), he was Assistant Professor (June 2013 to June 2016) at Centre of Biotechnology, University of Allahabad, Allahabad and Assistant Professor (June 2016 to October 2016) at Department of Biochemistry, Institute of Science, Banaras Hindu University (BHU).

  1. Qualified Graduate Aptitude Test in Engineering (GATE 2001) conducted by Indian Institute of Technology (IIT) Kanpur securing All India Rank 12thwith percentile 99.46                                                               
  2. Qualified CSIR-NET/JRF (2001) in Life Sciences  
  3. Qualified Indian Council of Medical Research (ICMR 2001) for award of Junior Research Fellowship (JRF)  
  4. Cash prize award of $ 115.00  for outstanding poster presentation by National Cancer Institute at Frederick and US Army, Fort Detrick, Frederick (USA)                                                       
  5. DST Young Scientist Grant Recipient, Government of India (2014)  
  6. Member of Indian Arctic Expedition Team 2014 during 18th August to 4th September 2014 to Ny-Alesund (Arctic, North pole) fully sponsored by “National Centre for Antarctic and Ocean Research”, Ministry of Earth Sciences, Government of India  
  7. Young Scientist Grant Recipient (CST, UP), Government of Uttar Pradesh (2016) 
  8. Organized a national conference "Biokumbh-2016" as Organizing Secretary at Centre of Biotechnology, University of Allahabad, Allahabad during 20-21 Feb, 2016
  9. Organized a summer course "Hands on Training in Molecular Biology and Genetic Engineering" as Organizing Secretary at Centre of Biotechnology, University of Allahabad, Allahabad during 20-27th May 2016
  10. Organized a summer course "Hands on Workshop in Stem Cell Biology Techniques" as Co-organizing Secretary at Centre of Biotechnology, University of Allahabad, Allahabad during 1-8th September 2016
S. No. Name of the project  Duration Sources
1. Establishment of Bacterial Biodiversity from Effluent of Leather Industry: search of a novel species (Principal Investigator)  August (2014-16)    UGC,
 New Delhi
2. Screening of Novel Psychrophilic Alkaline Protease from the Metagenome of Antarctic Soil (Principal Investigator)  August (2014-17)    DST,
New Delhi
3. Application of genetic engineering to enhance the lipid content in microalga Scenedesmus obliquus: a step towards biodiesel (Principal Investigator)  March (2017-20)   CST (UP),
Lucknow
4. Screening  of Novel   Antibiotics from the Metagenome of Himalayan Glacial Soil (Principal Investigator)  December (2017-20)   DRDO,
New Delhi
 
5. Construction of cold inducible expression system (Principal Investigator)  February (2017-20)     DBT,
New Delhi
6. Identification of Gene Responsible for Degradation of Poly (ethylene terephthalate) in Ideonella sakaiensis (Principal Investigator)  February (2017-20)    DBT,
New Delhi
7.
 
Characterization of psychrophilic lipase from Arctic soil (Principal Investigator)  February (2017-20)  IIT (BHU),
Varanasi
8. Bioremediation approach for removal of Atrazine herbicide from farming field (Principal Investigator)  January (2018-21)  IIT (BHU),
Varanasi

 
 

1. Hamid Y Dar, Shivani Chaturvedi, Karishma Srivastava, Zaffar Azam, Rajaneesh Anupam, Rajesh K Mondal, Geetanjali B Tomar, Ashish K Singh, Pradyumna K Mishra and Rupesh K Srivastava. 2017. Immunomodulatory Effects of Food Additives. Int J Immunother Cancer Res.  Vol. 3(1): Page 019-031.
 
2. Gupta K.K., Maurya S., Agarwal S., Kushwaha A., Kumar R., Pandey A.K., Singh A.K., Verma V. and Singh M.P. Antioxidant Assessment of Pleurotus sajor-caju Extracts Obtained through Hot Extraction Process. Cell Mol Biol 2016, 62(3): 129. (IF=1.43)
 
3.  Maurya S., Bhardwaj A.K., Gupta K.K., Agarwal S., Kushwaha A., Chaturvedi V., Pathak R.K., Gopal R., Uttam K.N., Singh A.K., Verma V. and Singh M.P. Green Synthesis of Silver Nanoparticles using Pluerotus and its Bactericidal Activity. Cell Mol Biol 2016, 62(3): 130. (IF=1.43)
 
4. Verma V., Tabassum N., Yadav C.B., Kumar M., Singh A.K., Singh M.P., Kumar A., Singh B. and Gautam S.K. Cord Blood Banking: An India Perspective. Cell Mol Biol 2016, 62(3): 133. (IF=1.43)
 
5. Verma V., Yadav C.B., Tabassum N., Kumar M., Singh M.P., Singh A.K., Kumar A., Singh B. and Gautam S.K. Stem Cell Therapy: The Methods in the Madness. Cell Mol Biol 2016, 62(3): 134. (IF=1.43)
 
6. Singh V., Singh M.P., Verma V., Singh P., Srivastava R. and Singh A.K. Characteristics of Cold     Adapted Enzyme and Its Comparison with Mesophilic and Thermophilic Counterpart. Cell Mol Biol (2016), 62(3):144 Review. (IF=1.43)
 
7.  *Jha, A., *Singh, A. K., Weissgerber, A. P., Freichel, M., Flockerzi, V., Flavell, R. A. and Jha, M. K. Essential role for Cavβ2 and Cav1 channels in Thymocyte development and T cell homeostasis. Science (Signaling). Vol. 8 (399) (2015), 1-10. (*Equal contribution). (IF=7.4)
 
8. *Singh, A. K., Singh, M. P. and Shivaji, S. Molecular Mechanisms of Cold Adaptation in Bacteria. Aperito Journal of Cellular and Molecular Biology. Vol. 1 (2015), 1-9 Review.
 
9. *Singh, A. K. and Singh, M. P. Importance of Algae as biofuel. Cell Mol Bio. Vol 60 (5) (2014), 106-109. Review (IF=1.46)
 
10. *Singh, A. K., Sad, K., Singh, S.K. and Shivaji, S. Regulation of gene expression at low temperature: role of cold-inducible promoters. Microbiology. Vol. 160 (2014), 1291-1297. Review (IF=3.12)
 
11. Kulkarni, V., Valentin, A., Rosati, M., Alicea, A., Singh, A.K., Jalah, R., Broderick, K.E., Saradesai, N.Y., Gall, S.L., Mothe, B., Brander, C., Rolland, M., Mullins, J.I., Pavlakis, G.N. and Felber, B.K. Altered Response Hierarchy and Increased T-Cell Breadth upon HIV-1 Conserved Element DNA Vaccination in Macaques. PloS one. Vol. 9 (2014), e86254. 13. (IF=3.4)
 
12. Kulkarni, V., Rosati, M., Bear, J., Pilkington, G.R., Jalah, R., Bergamaschi, C., Singh, A.K., Alicea, C., Chowdhary, B., Zhang, G.M., Kim, E.Y., Wolinsky, S.M., Huang, W., Guan, Y., Labranche, C., Montefioro, D.C., Broderick, K.E., Sardesai, N.Y., Valentin, A., Felber, B.K., Pavlakis, G.N. Comparison of intradermal and intramuscular delivery followed in vivo electroporation of SIV Env DNA in macaques. Hum. Vaccin. Immunother. (2013) Jun 28;9 (10). (IF=3.6)
 
13. Kulkarni, V., Margherita, R., Valentin, A., Ganneru, B., Singh, A.K., Yan, J., Rolland, M., Alicea, C., Beach, R.K., Zhang, G.M., Gall, S.l., Broderick, K., Sardesai, N.Y., Heckerman, D., Mothe, B., Brander, C., Weiner, D.B., Mullins, J.I., Pavlakis, G.N. and Felber, B.K. HIV-1 p24 gag derived Conserved Element DNA Vaccine Increase the Breadth of Immune Response in Mice. PlosOne. Vol 8, Issue 3 (2013) p1-13. (IF=3.4)
 
14. Srinivas, T.N.R., Singh, S.M., Pradhan, S., Pratibha, M.S., Kishore, K.H., Singh, A.K., Begum, Z., Prabagaran, S.R., Reddy, G.S.N. and Shivaji, S. Comparison of bacterial diversity in proglacial soil from Kafni glacier, Himalayan Mountain ranges, India, with the bacterial diversity of other glaciers in the world. Extremophiles. Vol. 15 (6) (2011) 673-90. (IF=2.346)
 
15. Shivaji, S., Pratibha, M.S., Sailaja, B., Kishore, K.H., Singh, A.K., Begum, Z., Uttam, A., Prabhagaran, S.R., Reddy, G.S. and Srinivas, T.N. Bacterial diversity of Soil in the vicinity of Pindari glacier, Himalayan mountain ranges, India, using culturable bacteria and 16SrRNA gene clones. Extremophiles. Vol. 15 (1) (2011) 1-22. (IF=2.346)
 
16. Pradhan, S., Srinivas, T.N., Pindi, P.K., Kishore, K.H., Begum, Z., Singh, P.K., Singh, A.K., Pratibha, M.S., Yasala, A., Reddy, G.S. and Shivaji, S. Bacterial diversity from Roopkund Glacier, Himalayan mountain ranges, India. Extremophiles; Vol. 14 (4) (2010) 377-95. (IF=2.346)

17. Sundareshwaran, V.R., Singh, A.K., Dubey, S. and Shivaji, S. Aspartate aminotransferase is involved in cold adaptation in psychrophilic Pseudomonas syringae. Arch Microbiology; Vol. 192 (8) (2010) 663-72. (IF=1.6)
 
18. Singh, A.K. and Shivaji, S. A cold-active and a heat-labile t-RNA modification GTPase from a psychrophilic bacterium Pseudomonas syringae (Lz4W). Res Microbiol; Vol. 161 (1): (2010) 46-50. (IF=2.1)
 
19. Gade, P., Singh, A.K., Roy, S.K., Reddy, S.P. and Kalvakolanu, D.V. Down regulation of the transcriptional mediator subunit Med1 contributes to the loss of expression of Metastasis associated dapk1 in cancer cells. Int J Cancer; Vol. 125 (7) (2009) 1566-74. (IF=7.36)
 
20. Singh, A.K., Pindi, P.K., Dubey, S., Sundareshwaran, V.R. and Shivaji, S. Importance of trmE for growth of the psychrophile Pseudomonas syringae at low temperature. Applied and Environmental Microbiology; Vol. 75 (13) (2009) 4419-26. (IF=4.04)
 
21. Chintalapati, S., Prakash, J.S.S., Singh, A.K., Ohtani, S., Suzuki, I., Murata, N. and Shivaji, S. Desaturase genes in a psychrotolerant Nostoc sp. are constitutively expressed at low temperature. Biochemical and Biophysical Research Communications. (2007);362(1):81-87. (IF=2.67)
 
22. Singh, A.K., Singh, V., Chaturvedi, V.K., Singh, M.P. and Verma, V. 2017. Molecular Techniques used for the Study of Soil Bacterial Diversity. In: Incredible World of Biotechnology, M.P. Singh, V. Verma and Ashish Kumar Singh (eds.), Nova Science Publishers, New York (USA), pp 67-78.
 
23. Kushwaha, A., Agarwal, S., Gupta, K.K., Maurya, S., Chaurasia, P.K., Singh, A.K. and Singh, M.P. 2017. Laccase Enzyme from White Rot Fungi: An Overview and Its Applications . In: Incredible World of Biotechnology, M.P. Singh, V. Verma and Ashish Kumar Singh (eds.), Nova Science Publishers, New York (USA), pp 25-42.
 
24. Verma, V., Tabassum, N., Yadav, C.B., Kumar, M., Kumar, A., Singh, L. Singh, M.P. and Singh, A.K. 2017. Mesenchymal Stem Cell Derived Exosomes: A Potential Novel Tool for Cancer Therapy. In: Incredible World of Biotechnology, M.P. Singh, V. Verma and Ashish Kumar Singh (eds.), Nova Science Publishers, New York (USA), pp 79-96.
 
25. Tabassum, N., Verma, V., Yadav, C.B., Kumar, M., Kumar, A., Mukherjee, A. Singh, M.P. and Singh, A.K. 2017. Regulatory Networks in Mesenchymal Stem Cells . In: Incredible World of Biotechnology, M.P. Singh, V. Verma and Ashish Kumar Singh (eds.), Nova Science Publishers, New York (USA), pp 97-118.
 
26. Yadav, C.B., Verma, V., Tabassum, N., Kumar, M., Kumar, A., Bajpayee, A.K., Dwivedi, S., Singh, M.P. and Singh, A.K. 2017. Progress, Problems and Prospects of Livestock Pluripotent Stem Cells. In: Incredible World of Biotechnology, M.P. Singh, V. Verma and Ashish Kumar Singh (eds.), Nova Science Publishers, New York (USA), pp 119-146.
 
27. Singh, A.K. and Pindi, P.K. 2012. Molecular Mechanisms of Temperature Sensing and Cold Adaptation in Bacteria. (Environmental Biotechnology edited by Ram Prasad and Arvind Kumar), Lambert Publishers, Germany, p 213-256.

28. V. K. Chaturvedi, Arkapravah Hangloo, R. K. Pathak, S. Agarwal, A. Kushwaha, K. K. Gupta, S. Maurya, A. K. Singh, V. Verma and M. P. Singh.The Molecular Land scape of Head and Neck Squamous Cell Carcinoma (HNSCC). In: Stem Cells from Culture Dish to Clinic ISBN: 978-1-53612-732-4 V. Verma, M.P. Singh  and M. Kumar (eds.), Nova Science Publishers, New York (USA).

29. V. K. Chaturvedi, Arkapravah Hangloo, R. K. Pathak, K. K. Gupta, V. Singh, A. K. Singh, V. Verma and M. P. Singh. Stem Cell Therapy for Neurodegenerative Disorders. In: Stem Cells from Culture Dish to Clinic ISBN: 978-1-53612-732-4 V. Verma, M.P. Singh  and M. Kumar (eds.), Nova Science Publishers, New York (USA).
 

Dr. SINGH’S LABORATORY MEMBERS

S.N. Cell Phone Email ID
1. +91-9599461859 manojkverma.rs.bce18@itbhu.ac.in
2. +91-9835476136 ajeetambuj@gmail.com
3. +91-9753162881 twinklebiswas.bce17@itbhu.ac.in
4. +91-7275774126 rahul.ranjan.bce14@itbhu.ac.in

 
 

The following positions are always available for talented and hardworking students to join our group: 
1. PDF (Post Doctoral Fellow)
2. Ph.D. 
3. Project JRF
4. Training