pandeeswar.chy's picture
Dr. Pandeeswar Makam
Assistant Professor
Department of Applied Chemistry, I.T. - B.H.U
pandeeswar.chy@itbhu.ac.in
.+91-7981714438
Area of Interest: 
Organic Synthesis, Peptide Self-assembly, Bio-Inspired Supramolecular Chemistry, Biomimetics, Bio-nanotechnology, Biomaterials Chemistry, Bioelectronics, Catalysis

Dr. Pandeeswar Makam
Assistant Professor
Department of Chemistry, Indian Institute of Technology 
(BHU)
Varanasi, Uttar Pradesh, India-221005
E-mail: pandeeswar.chy@itbhu.ac.in

Research Interest: Inspired by biological systems, our research focuses on integrating chemistry with biology and materials sciences and creating novel eco-friendly multifunctional nanomaterials that address the scientific problems related to energy, environmental, and health care.

Our research projects offer students significant knowledge and methodologies in organic synthesis as well as spectroscopic and microscopic characterization.

Selected Publications

  • Makam, P.; Yamijala, S. S. R. K. C., Tao, K.;   Shimon, L. J.W.; Eisenberg, D. S.; Sawaya, M. R.; Wong, B. M.; Gazit, E. Nonproteinaceous Hydrolase Comprised of Phenylalanine Metallo-Supramolecular Amyloid-like Structure. Nat. Catal. 2019, 2 (11), 977-985. (Impact Factor: 41.81). 
This article has been highlighted by Nature Catalysis News and Views as Nat Catal. 2019, 2, 949–950 and recommended by F1000Prime as being of special significance

 

  • Tao, K.; Makam, P.; Aizen, R.; Gazit, E. Self-Assembling Peptide Semiconductors. Science 2017, 358 (6365), eaam9756 (Impact Factor: 41.84)

 

  • Makam, P.; Gazit, E. Minimalistic Peptide Supramolecular Co-Assembly: Expanding the Conformational Space for Nanotechnology. Chem. Soc. Rev. 2018, 47 (10), 3406–3420 (Impact Factor: 54.56).

 

  • Makam, P.; Senanayak, S. P.; Narayan, K. S.; Govindaraju, T. Multi-Stimuli-Responsive Charge-Transfer Hydrogel for Room-Temperature Organic Ferroelectric Thin-Film Devices. J. Am. Chem. Soc. 2016, 138 (26), 8259–8268 (Impact Factor: 15.41).

 

  • Makam, P.; Shilpa, R.; Kandjani, A. E.; Periasamy, S. R.; Sabri, Y. M.; Madhu, C.; Bhargava, S. K.; Govindaraju, T. SERS and Fluorescence-Based Ultrasensitive Detection of Mercury in Water. Biosens. Bioelectron. 2018, 100, 556–564 (Impact Factor: 10.25).

Professional Experience:
 

  • Assistant Professor: Indian Institute of Technology (BHU), Varanasi, India (12/2020 – Present) 

 

  • Postdoctoral Research Fellow: Tel Aviv University, Israel with Prof. Ehud Gazit (10/2016 – 11/2020)

 

  • Research Associate: Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), India with Prof. T. Govindaraju (04/2016 – 10/2016)

Educational Background:
 

  • Ph.D.:  New Chemistry Unit, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), India with Prof. T. Govindaraju (2016)

 

  • M.S.: Chemistry and Physics of Materials Unit, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), India (2011)

 

  • B.Sc.: Bhavan's New Science College, Osmania University, Telangana, India (2007)

 Google Scholar: https://scholar.google.co.in/citations?user=XQ3YCEsAAAAJ&hl=en

  • Chen, Y.; Yang, Y.; Orr, A. A.; Makam, P.; Redko, B.; Haimov, E.; Wang, Y.; Shimon, L. J. W.; Rencus‐Lazar, S.; Ju, M.; et al. Self‐Assembled Peptide Nano‐Superstructure towards Enzyme Mimicking Hydrolysis. Angew. Chemie Int. Ed. 2021. https://doi.org/10.1002/anie.202105830 (I.F. 15.33)

 

  • Tao, K.; Orr, A. A.; Hu, W.; Makam, P.; Zhang, J.; Geng, Q.; Li, B.; Jakubowski, J. M.; Wang, Y.; Tamamis, P.; et al. EDTA-Mimicking Amino Acid–Metal Ion Coordination for Multifunctional Packings. J. Mater. Chem. A 2021. https://doi.org/10.1039/D1TA03985G (I.F. 12.7)

 

  • Arnon, Z. A.; Kreiser, T.; Yakimov, B.; Brown, N.; Aizen, R.; Shaham-Niv, S.; Makam, P.; Qaisrani, M. N.; Poli, E.; Ruggiero, A.; et al. On-off Transition and Ultrafast Decay of Amino Acid Luminescence Driven by Modulation of Supramolecular Packing. iScience 2021, 24 (7), 102695 

 

  • Kavitha, B. S.; Sridevi, S.; Makam, P.; Ghosh, D; Govindraju, T.; Asokan, S.; and Sood, A. K.; Highly Sensitive and Rapid Detection of Mercury in water Using Functionalized Etched Fiber Bragg Grating Sensors. Sens. Actuators B Chem. 2021, 333, 129550. (I.F. 7.1).

 

  • Mondal, A. K.; Brown, N.; Mishra, S.; Makam, P.; Wing, D.; Gilead, S.; Wiesenfeld, Y.; Leitus, G.; Shimon, L. J. W.; Carmieli, R.; et al. Long-Range Spin-Selective Transport in Chiral Metal–Organic Crystals with Temperature-Activated Magnetization. ACS Nano 2020, 14 (12), 16624–16633 (IF. 15.88).

 

  • Ji, W.; Yuan, C.; Chakraborty, P.; Makam, P.; Bera, S.; Rencus-Lazar, S.; Li, J.; Yan, X.; Gazit, E. Coassembly-Induced Transformation of Dipeptide Amyloid-Like Structures into Stimuli-Responsive Supramolecular Materials. ACS Nano 2020, 14, 7181–7190. (I.F. 15.88).

 

  • Tao, K.; Chen, Y.; Orr, A. A.; Tian, Z.; Makam, P.; Gilead, S.; Si, M.; Rencus‐Lazar, S.; Qu, S.; Zhang, M.; et al. Enhanced Fluorescence for Bioassembly by Environment‐Switching Doping of Metal Ions. Adv. Funct. Mater. 2020, 30 (10), 1909614. (I.F. 18.88).

 

  • Zaguri, D.; Shaham-Niv, S.; Chakraborty, P.; Arnon, Z.; Makam, P.; Bera, S.; Rencus-Lazar, S.; Stoddart, P. R.; Gazit, E.; Reynolds, N. P. Nanomechanical Properties and Phase Behavior of Phenylalanine Amyloid Ribbon Assemblies and Amorphous Self-Healing Hydrogels. ACS Appl. Mater. Interfaces 2020, 12 (19), 21992–22001. (I.F. 9.22).

 

  • Donnell, J. O.; Guerin, S.; Makam, P.; Cazade, P. A.; Haq, E. U.; Tao, K.; Gazit, E.; Silien, C; Soulimane, T.; Thompson, D; Tofail, S. A.; Atomistic-Benchmarking Towards a Protocol Development for Rapid Quantitative Metrology of Piezoelectric Biomolecular Materials. Appl. Mater. Today 2020, 21, 100818. (I.F. 10.04).

 

  • Chen, Y.; Tao, K.; Ji, W.; Makam, P.; Rencus-Lazar, S.; Gazit, E. Self-Assembly of Cyclic Dipeptides: Platforms for Functional Materials. Protein Pept. Lett. 2020, 27. In press (I.F. 1.15)

 

  • Makam, P.; Yamijala, S. S. R. K. C., Tao, K.;   Shimon, L. J.W.; Eisenberg, D. S.; Sawaya, M. R.; Wong, B. M.; Gazit, E. Nonproteinaceous Hydrolase Comprised of Phenylalanine Metallo-Supramolecular Amyloid-like Structure. Nat. Catal. 2019, 2 (11), 977-985. (I.F. 41.81).
 This article has been highlighted by Nature Catalysis News and Views as Nat Catal. 2019, 2, 949–950 and recommended by F1000Prime as being of special significance

 

  • Tao, K.; Xue, B.; Li, Q.; Hu, W.; Shimon, L. J. W.; Makam, P.; Si, M.; Yan, X.; Zhang, M.; Cao, Y.; et al. Stable and Optoelectronic Dipeptide Assemblies for Power Harvesting. Mater. Today 2019, 30, 10-16 (I.F. 31.04).

 

  • Makam, P.; Gazit, E. Minimalistic Peptide Supramolecular Co-Assembly: Expanding the Conformational Space for Nanotechnology. Chem. Soc. Rev. 2018, 47 (10), 3406–3420. (I.F. 54.56).

 

  • Tao, K.; Fan, Z.; Sun, L.; Makam, P.; Tian, Z.; Ruegsegger, M.; Shaham-Niv, S.; Hansford, D.; Aizen, R.; Pan, Z.; et al. Quantum Confined Peptide Assemblies with Tunable Visible to Near-Infrared Spectral Range. Nat. Commun. 2018, 9 (1), 3217. (I.F. 14.91).

 

  • Makam, P.; Shilpa, R.; Kandjani, A. E.; Periasamy, S. R.; Sabri, Y. M.; Madhu, C.; Bhargava, S. K.; Govindaraju, T. SERS and Fluorescence-Based Ultrasensitive Detection of Mercury in Water. Biosens. Bioelectron. 2018, 100, 556–564. (I.F. 10.25).

 

  • Madhu, C.*; Roy, B.*; Makam, P.*; Govindaraju, T. Bicomponent β-Sheet Assembly of Dipeptide Fluorophores of Opposite Polarity and Sensitive Detection of Nitro-Explosives. Chem. Commun. 2018, 54 (18), 2280–2283. (I.F. 6.22).

 

  • Ramesh, M.*; Makam, P.*; Voshavar, C.*; Khare, H.; Rajasekhar, K.; Ramakumar, S.; Govindaraju, T. L-Dopa and Dopamine Conjugated Naphthalenediimides Modulate Amyloid β Toxicity. Org. Biomol. Chem. 2018, 16 (41), 7682–7692. (I.F. 3.41).

 

  • Tao, K.; Makam, P.; Aizen, R.; Gazit, E. Self-Assembling Peptide Semiconductors. Science 2017, 358 (6365), eaam9756. (I.F. 41.84).

 

  • Makam, P.; Senanayak, S. P.; Narayan, K. S.; Govindaraju, T. Multi-Stimuli-Responsive Charge-Transfer Hydrogel for Room-Temperature Organic Ferroelectric Thin-Film Devices. J. Am. Chem. Soc. 2016, 138 (26), 8259–8268. (I.F. 15.14).

 

  • Makam, P.; Senanayak, S. P.; Govindaraju, T. Nanoarchitectonics of Small Molecule and DNA for Ultrasensitive Detection of Mercury. ACS Appl. Mater. Interfaces 2016, 8 (44), 30362–30371. (I.F. 9.22).

 

  • Makam, P.; Govindaraju, T. Engineering Molecular Self-Assembly of Perylene Diimide through PH-Responsive Chiroptical Switching. Mol. Syst. Des. Eng. 2016, 1 (2), 202–207. (I.F. 4.39).

 

  • Makam, P.; Khare, H.; Ramakumar, S.; Govindaraju, T. Crystallographic Insight-Guided Nanoarchitectonics and Conductivity Modulation of an n-Type Organic Semiconductor through Peptide Conjugation. Chem. Commun. 2015, 51 (39), 8315–8318. (I.F. 6.22).

 

  • Makam, P.; Govindaraju, T. Bioinspired Nanoarchitectonics of Naphthalene Diimide to Access 2D Sheets of Tunable Size, Shape, and Optoelectronic Properties. J. Inorg. Organomet. Polym. Mater. 2015, 25 (2), 293–300. (I.F. 3.54).

 

  • Dwivedi, A. K.*; Makam, P.*; Govindaraju, T. Assembly Modulation of PDI Derivative as a Supramolecular Fluorescence Switching Probe for Detection of Cationic Surfactant and Metal Ions in Aqueous Media. ACS Appl. Mater. Interfaces 2014, 6 (23), 21369–21379. (I.F. 9.22).

 

  • Makam, P.; Khare, H.; Ramakumar, S.; Govindaraju, T. Biomimetic Molecular Organization of Naphthalene Diimide in the Solid State: Tunable (Chiro-) Optical, Viscoelastic and Nanoscale Properties. RSC Adv. 2014, 4 (39), 20154–20163. (I.F. 3.36).

 

  • Makam, P.; Govindaraju, T. Green-Fluorescent Naphthalene Diimide: Conducting Layered Hierarchical 2D Nanosheets and Reversible Probe for Detection of Aromatic Solvents. RSC Adv. 2013, 3 (29), 11459. (I.F. 3.36).

 

  • Makam, P.; Avinash, M. B.; Govindaraju, T. Chiral Transcription and Retentive Helical Memory: Probing Peptide Auxiliaries Appended with Naphthalenediimides for Their One-Dimensional Molecular Organization. Chem. Eur. J. 2012, 18 (16), 4818–4822. (I.F. 5.23). This work is highlighted as Inside Cover Picture.

 

  • Maitra, U.; Makam, P.; Govindaraju, T. Covalent Crosslinking of Carbon Nanostructures. J. Chem. Sci. 2012, 124 (3). (I.F. 1.52).

 

  • Govindaraju, T.; Makam, P.; Jayaramulu, K.; Jaipuria, G.; Atreya, H. S. Spontaneous Self-Assembly of Designed Cyclic Dipeptide (Phg-Phg) into Two-Dimensional Nano- and Mesosheets. Supramol. Chem. 2011, 23 (7), 487–492. (I.F. 1.82).

*equal contribution
Impact Factor (I.F.)